MIPAS-ENVISAT limb-sounding measurements: trade-off study for improvement of horizontal resolution

The Michelson Interferometer for Passive Atmospheric Sounding (MIPAS) is a limb-scanning spectrometer that has operated onboard the Environmental Satellite since the end of March 2002. Common features of limb-scanning experiments are both high vertical resolution and poor horizontal resolution. We exploit the two-dimensional geo-fit retrieval approach [Appl. Opt. 40, 1872-1875 (2001)] to investigate the possibility of improving the horizontal resolution of MIPAS measurements. Two different strategies are considered for this purpose, one exploiting the possibility (offered by the geo-fit analysis method) for an arbitrary definition of the retrieval grid, the other based on the possibility of saving measurement time by degrading the spectral resolution of the interferometer. The performances of the two strategies are compared in terms of the trade-off between the attained horizontal resolution and the retrieval precision. We find that for ozone it is possible to improve by a factor of 2 the horizontal resolution, which in the nominal measurement plan is approximately 530 km. This improvement corresponds to a degradation of the retrieval precision, which on average varies from a factor of 1.4 to 2.5, depending on the adopted spectral resolution.     

Stigmatic spectrometers for extended sources: design with toroidal varied-line-space gratings

Performances are presented of three classes of imaging slit spectrometers for extended sources with aberration-corrected gratings. A general analytical expression for minimizing off-axis grating aberrations is obtained, and it is demonstrated that these aberrations are minimized when the spectrometer is operated at a magnification higher than unity. Classical designs with toroidal uniform-line-spaced (TULS) or spherical varied-line-space (SVLS) gratings are compared with a new class of designs that utilize toroidal varied-line-space (TVLS) gratings. Although TULS and SVLS designs with two stigmatic points can be designed to operate at near-unity magnification with excellent on-axis spectral and spatial resolutions, they cannot be made to satisfy the general off-axis condition, and so their off-axis performances are not optimum. On the contrary TVLS designs with two stigmatic points can be operated at almost any magnification, thus satisfying the off-axis condition perfectly. Such designs are suitable for imaging spectrometer observations that require an extended field of view.     

Optimisation of the throttling system in a CO2 refrigerating machine

This paper is an answer to the need of finding the optimal solution for the throttling system in refrigerating machines using CO₂ as working fluid; such a solution must combine reliability, low installation cost and high energy efficiency. To this purpose, different expansion systems are compared by means of a simulation programme, including a new one, operating with a differential valve, a liquid receiver and a thermostatic valve. The typical compression refrigerating cycle performed by CO₂ involves transcritical operations and therefore the upper pressure needs to be adjusted to the optimal value, that, unlike the traditional cycle, is not determined by heat transfer. The innovative system here proposed shows an intrinsic self-adjusting capability that leads to COP values quite close to the maximum ones when a fixed suitable value of the differential pressure is chosen, even if the temperature of the secondary fluid varies to a large extent.     

Festina lente: learning and inertia among Italian automobile producers, 1896-1981

Based on the premise that learning and inertia develop and operatein organizations simultaneously, this paper examines under whatconditions adaptation or selection will take place. We haveanalyzed the process of technological scope expansion amongItalian automobile firms, and found that firms prone to expandingtheir technological competencies tend to be either specificallyorganized to benefit from variation-based learning or do soin response to pressures from competitive intensity in theirenvironment. But these effects hinge on the structure of themarket that evolves as the industry consolidates. We also examinethe failure rates of Italian auto firms and find that implementinga core change generates negative repercussions for survivalbut this effect can be countered by properties of the organizationaldesign that facilitate variation-based learning. Our resultssuggest that organization theory will benefit if ecologicaland learning theories are further integrated in future research.     

Characterization of microstructured optical fibers for wideband dispersion compensation

Microstructured optical fibers (MOFs) with small hole-to-hole spacing and large airholes are designed to compensate the anomalous dispersion and the dispersion slope of single-mode fibers. The geometrical parameters that characterize triangular MOFs are chosen to optimize the fiber length and the compensation over a wide wavelength range. A proper design of the photonic crystal fiber geometry allows us to achieve dispersion values of approximately -1700 ps nm(-1) km(-1) at 1550 nm and to compensate the dispersion of standard fibers within +/- 0.5 ps nm(-1) km(-1) over a 100-nm range. The MOF dispersion properties have been studied by means of a numerical simulator for modal analysis based on the finite-element method.     

A cyclic CCK8 analogue selective for the cholecystokinin type A receptor: design, synthesis, NMR structure and binding measurements

A cyclic CCK8 analogue, cyclo(29,34)[Dpr(29),Lys(34)]-CCK8 (Dpr=L-2,3-diaminopropionic acid), has been designed on the basis of the NMR structure of the bimolecular complex between the N-terminal fragment of the CCK(A) receptor and its natural ligand CCK8. The conformational features of cyclo(29,34)[Dpr(29),Lys(34)]-CCK8 have been determined by NMR spectroscopy in aqueous solution and in water containing DPC-d(38) micelles (DPC=dodecylphosphocholine). The structure of the cyclic peptide in aqueous solution is found to be in a relaxed conformation, with the backbone and Dpr29 side chain atoms making a planar ring and the N-terminal tripeptide extending approximately along the plane of this ring. In DPC/water, the cyclic peptide adopts a "boat-shaped" conformation, which is more compact than that found in aqueous solution. The cyclic constraint between the Dpr29 side chain and the CCK8 carboxyl terminus (Lys34) introduces a restriction in the backbone conformational freedom. However, the interaction of cyclo(29,34)[Dpr(29),Lys(34)]-CCK8 with the micelles still plays an important role in the stabilisation of the bioactive conformation. A careful comparison of the NMR structure of the cyclic peptide in a DPC micelle aqueous solution with the structure of the rationally designed model underlines that the turn-like conformation in the Trp30-Met31 region is preserved, such that the Trp30 and Met31 side chains can adopt the proper spatial orientation to interact with the CCK(A) receptor. The binding properties of cyclo(29,34)[Dpr(29),Lys(34)]-CCK8 to the N-terminal receptor fragment have been investigated by fluorescence spectroscopy in a micellar environment. Estimates of the apparent dissociation constant, K(d), were in the range of 70-150 nM, with a mean value of 120+/-27 nM. Preliminary nuclear medicine studies on cell lines transfected with the CCK(A) receptor indicate that the sulfated-Tyr derivative of cyclo(29,34)[Dpr(29),Lys(34)]-CCK8 displaces the natural ligand with an IC(50) value of 15 microM.     

Correlations between jointing and seismic velocities in highly fractured rock masses

The paper presents the results of a study of heavily fractured calcareous rock masses outcropping in southern Italy based on both the unidimensional joint frequency (Nl) and rock quality designation (RQD) of rock cores and seismic velocity data from laboratory and down-hole tests. The in situ longitudinal wave velocities (v) were always very low and were correlated with both Nl and RQD. Between 1 and 2 km/s, small increases in velocity were associated with a considerable decrease in Nl and significant increase in RQD value. A velocity of 1.22 km/s corresponded to an RQD value of 0. The study indicated that the simple correlation proposed by the International Society for Rock Mechanics to evaluate the RQD from the unidimensional joint frequency can underestimate the results for heavily fractured rock masses, but that good correlations can be obtained between RQD and seismic velocity. Electronic Publication     

Constructive nonlinear anti-windup design for exponentially unstable linear plants

In this paper we give a constructive method for anti-windup design for general linear saturated plants with exponentially unstable modes. The constructive solution is independent of the controller dynamics so that the size of the (necessarily bounded) operating region in the exponentially unstable directions of the plant state space is large. Desirable properties of the closed-loop are formally proved and shown to induce a very desirable behavior on a MIMO example with two exponentially unstable modes.     

Context-aware handoff middleware for transparent service continuity in wireless networks

Advances in wireless networking and content delivery are enabling new challenging provisioning scenarios where a growing number of users access continuous services, e.g., audio/video streaming, while moving among different points of attachment to the Internet, possibly with different connectivity technologies, e.g., Wi-Fi, Bluetooth, and cellular 3G. That calls for novel middlewares capable of dynamically personalizing service provisioning to the characteristics of client environments, in particular to discontinuities in wireless resource availability due to handoffs. The paper proposes a novel middleware solution, called Mobile agent-based Ubiquitous multimedia Middleware (MUM), that performs effective and context-aware handoff management to transparently avoid service interruptions during both horizontal and vertical handoffs. MUM exploits the full visibility of wireless connections available and their handoff implementations (handoff awareness), of service quality requirements and handoff-related quality degradations (QoS awareness), and of network topology and local resource availability (location awareness); that visibility enables MUM to provide original solutions for handoff prediction, multimedia continuity via adaptive data buffering/pre-fetching, and proactive re-addressing/rebinding.     

Employing virtual humans for education and training in X3D/VRML worlds

Web-based education and training provides a new paradigm for imparting knowledge; students can access the learning material anytime by operating remotely from any location. Web3D open standards, such as X3D and VRML, support Web-based delivery of Educational Virtual Environments (EVEs). EVEs have a great potential for learning and training purposes, by allowing one to circumvent physical, safety, and cost constraints. Unfortunately, EVEs often leave to the user the onus of taking the initiative both in exploring the environment and interacting with its parts. A possible solution to this problem is the exploitation of virtual humans acting as informal coaches or more formal instructors. For example, virtual humans can be employed to show and explain maintenance procedures, allowing learners to receive more practical explanations which are easier to understand. However, virtual humans are rarely used in Web3D EVEs, since the programming effort to develop and re-use them in different environments can be considerable. In this paper, we present a general architecture that allows content creators to easily integrate virtual humans into Web3D EVEs. To test the generality of our solution, we present two practical examples showing how the proposed architecture has been used in different educational contexts.