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91.
Alexander Kromka Lubica Grausova Lucie Bacakova Jiri Vacik Bohuslav Rezek Milan Vanecek Oliver A. Williams Ken Haenen 《Diamond and Related Materials》2010,19(2-3):190-195
The impact of boron doping level of nanocrystalline diamond (NCD) films on the character of cell growth (i.e., adhesion, proliferation and differentiation) is presented. Intrinsic and boron-doped NCD films were grown on Si/SiO2 substrates by microwave plasma CVD process. The boron-doped samples were grown by adding trimethylboron (TMB) to the gas mixture of methane and hydrogen. Highly resistive (0 ppm), semiconducting (133 or 1000 ppm), and metallic-like (6700 ppm) NCD films were tested as the artificial substrates for the cultivation of osteoblast-like MG 63 cells. The conductivity and surface charge increased monotonically with the increasing boron content. All NCD substrates showed good biocompatibility and stimulated the adhesion and growth of MG 63 cells. Higher osteocalcin concentration (by more than 30%) for the cells growing on 1000 and 6700 ppm boron-doped NCD films was found which indicates an enhancement in the cell growth biochemistry. 相似文献
92.
Lucie Kalvodova 《European Journal of Lipid Science and Technology》2010,112(10):1067-1067
93.
Ivana Kopova Lucie Bacakova Vasily Lavrentiev Jiri Vacik 《International journal of molecular sciences》2013,14(5):9182-9204
Fullerenes are nanoparticles composed of carbon atoms arranged in a spherical hollow cage-like structure. Numerous studies have evaluated the therapeutic potential of fullerene derivates against oxidative stress-associated conditions, including the prevention or treatment of arthritis. On the other hand, fullerenes are not only able to quench, but also to generate harmful reactive oxygen species. The reactivity of fullerenes may change in time due to the oxidation and polymerization of fullerenes in an air atmosphere. In this study, we therefore tested the dependence between the age of fullerene films (from one week to one year) and the proliferation, viability and metabolic activity of human osteosarcoma cells (lines MG-63 and U-2 OS). We also monitored potential membrane and DNA damage and morphological changes of the cells. After seven days of cultivation, we did not observe any cytotoxic morphological changes, such as enlarged cells or cytosolic vacuole formation. Furthermore, there was no increased level of DNA damage. The increasing age of the fullerene films did not cause enhancement of cytotoxicity. On the contrary, it resulted in an improvement in the properties of these materials, which are more suitable for cell cultivation. Therefore, fullerene films could be considered as a promising material with potential use as a bioactive coating of cell carriers for bone tissue engineering. 相似文献
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Reviews the book, Psychologie positive et personnalite (Positive psychology and personality, activation of resources) by Firouzeh Mehran (2010). This is an interesting book on a captivating subject that has been little examined. Psychology has produced much more research on human distress than on people’s well-being. On the practical level, it presents a variety of techniques applicable in therapy. On the personal level, the book encourages the reader to modify current habits and suggests several ways of doing so. The book begins with personality theories prior to positive psychology that focused on healthy aspects of human existence; then examines current trends. Among other aspects, the author discusses spirituality and humor, their utility in clinical work and future possibilities. This is a theoretical book that offers practical ideas on acquiring healthy attitudes. Many techniques are suggested for therapists, and their clients, such as the principles and exercises of meditation in the mindfulness approach. It is not only an instructive source of knowledge but a tool for change and professional development. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
99.
Izabella Rajzer Elzbieta Menaszek Lucie Bacakova Monika Rom Marta Blazewicz 《Journal of materials science. Materials in medicine》2010,21(9):2611-2622
In the present study we focused on the in vitro and in vivo evaluation of two types of carbon fibres (CFs): hydroxyapatite modified carbon fibres and porous carbon fibres. Porous CFs used as scaffold for tissues regeneration could simultaneously serve as a support for drug delivery or biologically active agents which would stimulate the tissue growth; while addition of nanohydroxyapatite to CFs precursor can modify their biological properties (such as bioactivity) without subsequent surface modifications, making the process cost and time effective. Presented results indicated that fibre modification with HAp promoted formation of apatite on the fibre surface during incubation in simulated body fluid. The materials biocompatibility was determined by culturing human osteoblast-like cells of the line MG 63 in contact with both types of CFs. Both tested materials gave good support to adhesion and growth of bone-derived cells. Materials were implanted into the skeletal rat muscle and a comparative analysis of tissue reaction to the presence of the two types of CFs was done. Activities of marker metabolic enzymes: cytochrome c oxidase (CCO) and acid phosphatase were examined to estimate the effect of implants on the metabolic state of surrounding tissues. Presented results evidence the biocompatibility of porous CFs and activity that stimulates the growth of connective tissues. In case of CFs modified with hydroxyapatite the time of inflammatory reaction was shorter than in case of traditional CFs. 相似文献
100.
Samuel Dorey Fanny Gaston Nina Girard-Perier Nathalie Dupuy Sylvain R.A. Marque Lucie Delaunay 《应用聚合物科学杂志》2020,137(44):49361
The potential changes of single-use plastic materials (EVA/EVOH/EVA multilayer film in this study) used in biopharmaceutical and food-packaging industries are investigated after several gamma irradiation doses: 30, 50, 115, and 270 kGy, and for nonsterilized samples (0 kGy) from a point of view of mechanical properties, thermal properties and permeability properties. Tensile tests, differential scanning calorimetry (DSC), oxygen transmission rate (OTR) and water vapor transmission rate (WVTR) are performed on the multilayer film. For irradiation doses below 50 kGy, thermal and water vapor barrier properties are not altered. For higher doses (50 to 270 kGy), mechanical, thermal and water vapor barrier properties are slightly altered whereas oxygen barrier property decreases from 13 to 27 cm3.m−2.day−1. This slight change is shown not to happen due to chain entanglement or chain mobility loss in the amorphous phase of the different polymers. It rather comes from a change of the chemical environment of the EVOH layer. 相似文献