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71.
S. L. Campanelli G. Casalino A. D. Ludovico C. Bonserio 《The International Journal of Advanced Manufacturing Technology》2013,66(9-12):1777-1784
Laser milling (LM) can be classified as a layer manufacturing process in which the material is removed by a laser beam by means of the ablation mechanism. It is a laser machining process which uses a laser beam to produce 3D shapes into a wide variety of materials. It is also known as laser ablation. It shows clear advantages versus the traditional milling such as the unlimited choice of materials, the direct use of computer-aided design structure data, the high geometric flexibility, and the touchless tool. LM requires the selection of optimal machining parameters for the job. Unlike the mechanical milling and the mechanical incision, the depth of the single removed layer is chosen at the beginning as input parameter of the process. In LM, the ablated depth depends from the process parameters such as laser power, scan speed, pulse duration, and pulse frequency. This work aims to develop an algorithm that can predict the parameters necessary to execute the material removal with a preset ablation depth. Using the results of an experimental campaign, the laser milling process was modeled by means of a back-propagation artificial neural network. Then, an iterative algorithm, based on the previous trained neural network, permitted to calculate the scanning velocity and pulse frequency that approached for the best the preset ablation depth. The developed approach represents a mean for the rational selection of laser ablation process parameters. It can be performed in an intuitive manner since it uses simple artificial intelligence like the artificial neural network. 相似文献
72.
Rossella DOria Valentina Annamaria Genchi Cristina Caccioppoli Isabella Calderoni Nicola Marrano Giuseppina Biondi Anna Borrelli Ludovico Di Gioia Francesco Giorgino Luigi Laviola 《International journal of molecular sciences》2022,23(22)
Obesity with its associated complications represents a social, economic and health problem of utmost importance worldwide. Specifically, obese patients carry a significantly higher risk of developing cardiovascular disease compared to nonobese individuals. Multiple molecular mechanisms contribute to the impaired biological activity of the distinct adipose tissue depots in obesity, including secretion of proinflammatory mediators and reactive oxygen species, ultimately leading to an unfavorable impact on the cardiovascular system. This review summarizes data relating to the contribution of the main adipose tissue depots, including both remote (i.e., intra-abdominal, hepatic, skeletal, pancreatic, renal, and mesenteric adipose fat), and cardiac (i.e., the epicardial fat) adipose locations, on the cardiovascular system. Finally, we discuss both pharmacological and non-pharmacological strategies aimed at reducing cardiovascular risk through acting on adipose tissues, with particular attention to the epicardial fat. 相似文献
73.
Gabriele Giancane Andrés Ruland Vito Sgobba Daniela Manno Antonio Serra Gianluca M. Farinola Omar Hassan Omar Dirk M. Guldi Ludovico Valli 《Advanced functional materials》2010,20(15):2481-2488
An alkoxy‐substituted poly(phenylene thiophene) is used in order to suspend single‐walled carbon nanotubes in an organic solvent. The suspension is spread on the air–water interface of a Langmuir trough and the floating film is characterized by means of Brewster angle microscopy and UV‐visible reflection spectroscopy and the compression isotherm is recorded. The polymer/carbon‐nanotube blend is transferred onto different substrates using the Langmuir–Blodgett technique. AFM measurements indicate the formation of globular structures for the samples transferred at low surface‐pressure values and a tubular morphology for high‐pressure‐deposited samples. AFM analysis is repeated on a sample exposed to soft X‐rays for about 5 h and a highly organized structure of bundles of carbon nanotubes rises up. Samples with different numbers of layers are transferred onto ITO substrates by means of the Langmuir–Blodgett method and are tested as photocathodes in a photo‐electrochemical cell. A Voc of 0.18 V, an Isc of 85.8 mA, FF of 40.0%, and η of (6.23 × 10?3)% are obtained. 相似文献
74.
Ludovico Minati Ileana Zucca Gabriella Carcassola Michele Occhipinti Roberto Spreafico Maria Grazia Bruzzone 《Magma (New York, N.Y.)》2010,23(2):115-121
Object
To investigate whether spacing (Δ) and duration (δ) of the diffusion-sensitizing gradient pulses differentially affect exponential (D′), biexponential (D slow, D fast and f slow) and diffusional kurtosis (D and K) model parameters. 相似文献75.
Cademartiri L Bishop KJ Snyder PW Ozin GA 《Philosophical transactions. Series A, Mathematical, physical, and engineering sciences》2012,370(1969):2824-2847
A 1980 poem by Alan Mackay outlines his aspiration 'to see what all have seen but think what none have thought': a daunting task, which he accomplished not once, but several times. A 'truly myriadminded, manysided man-a veritable triacontahedron' in the words of his colleagues and friends, Alan Mackay pursued a lifelong interest in the problems of morphogenesis and form, a comprehension of which necessitated him crisscrossing the borders of the inanimate and animate world of soft and hard materials, through the integration of concepts and methods of chemistry, physics, mathematics and biology. In other words, he realized in his time a genuinely interdisciplinary approach to complex problems that still to this day remains beyond much of the academic community. Being invited to contribute a paper on the theme 'beyond crystals', we naturally wondered how Alan Mackay would think about the world of nanoscale self-assembly where so much depends on shape and form. 相似文献
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77.
D Zheng JE Ferguson CA Macera Y Boateng SP Temple FC Wheeler 《Canadian Metallurgical Quarterly》1997,93(3):93-98
As a result of the neuropathologic process of Alzheimer's disease (AD), significant changes occur in neuromotor function (e.g., paratonia and compulsive grasping). These changes become manifest in the moderately severe stage of AD, when patients begin to require ongoing assistance with activities of daily life (ADL), and they are prominent in the severe stage of AD, when patients are continuously dependent on a caregiver. Patients in these stages often display behavioral disturbances during care activities. These disturbing behaviors result not only from cognitive impairment, but also from a patient's physical inability to cooperate with the caregiver. When care management strategies take into account the characteristic physical restrictions resulting from the neuromotor changes that accompany advanced AD, the caregiving process may be significantly facilitated. 相似文献
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79.
Riwal Lefort Ludovico Fusco Olivier Pertz François Fleuret 《Pattern Analysis & Applications》2017,20(1):87-100
A RNA interference, also called a gene knockdown, is a biological technique which consists of inhibiting a targeted gene in a cell. By doing so, one can identify statistical dependencies between a gene and a cell phenotype. However, during such a gene inhibition process, additional genes may also be modified. This is called the “off-target effect”. The consequence is that there are some additional phenotype perturbations which are “off-target”. In this paper, we study new machine learning tools that both model the cell phenotypes and remove the “off-target effect”. We propose two new automatic methods to remove the “off-target” components from a data sample. The first method is based on vector quantization (VQ). The second method we propose relies on a classification forest. Both methods rely on analyzing the homogeneity of several repetitions of a gene knockdown. The baseline we consider is a Gaussian mixture model whose parameters are learned under constraints with a standard Expectation–Maximization algorithm. We evaluate these methods on a real data set, a semi-synthetic data set, and a synthetic toy data set. The real data set and the semi-synthetic data set are composed of cell growth dynamic quantities measured in time laps movies. The main result is that we obtain the best recognition performance with the probabilistic version of the VQ-based method. 相似文献
80.