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41.
Chengjun Yao Yixun Liu Jianhua Yao Dongxiao Zhuang Jinsong Wu Zhiyong Qin Ying Mao Liangfu Zhou 《Computer methods and programs in biomedicine》2014
Background
Preoperatively acquired diffusion tensor image (DTI) and blood oxygen level dependent (BOLD) have been proved to be effective in providing more anatomical and functional information; however, the brain deformation induced by brain shift and tumor resection severely impairs the correspondence between the image space and the patient space in image-guided neurosurgery.Method
To address the brain deformation, we developed a hybrid non-rigid registration method to register high-field preoperative MRI with low-field intra-operative MRI in order to recover the deformation induced by brain shift and tumor resection. The registered DTI and BOLD are fused with low-field intra-operative MRI for image-guided neurosurgery.Results
The proposed hybrid registration method was evaluated by comparing the landmarks predicted by the hybrid registration method with the landmarks identified in the low-field intra-operative MRI for 10 patients. The prediction error of the hybrid method is 1.92 ± 0.54 mm, and the compensation accuracy is 74.3 ± 5.0%. Compared to the landmarks far from the resection region, those near the resection region demonstrated a higher compensation accuracy (P-value = .003) although these landmarks had larger initial displacements.Conclusions
The proposed hybrid registration method is able to bring preoperatively acquired BOLD and DTI into the operating room and compensate for the deformation to augment low-field intra-operative MRI with rich anatomical and functional information. 相似文献42.
利用重组NS4抗原及合成肽5-11抗原分别检测5例输血后丙型肝炎患者的系列血清136份,并与HCV总抗体及HCVRNA检测结果比较,发现抗NS4抗体的动态变化虽然有两种模式,但在多数情况下为一种模式,即抗体阳转后很少转阴,并且其动态变化基本与总抗体相似。同时发现2例病人抗NS4抗体阳转时间早于总抗体,因此,推测HCV检测试剂中增加NS4抗原可能对提高HCV诊断试剂的灵敏度有一定意义。 相似文献
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RT-PCR法检测庚型肝炎病毒C(GBV-C)RNA 总被引:2,自引:0,他引:2
应用RT-PCR法在非甲~非戊型肝炎患者血清及单采浆站供血员血浆中检测到GBV-CRNA,扩增产物经序列测定进一步确证,在30例非甲~非戊型肝炎患者中阳性率为6.6%;在600例单采浆供血者血浆中阳性率为0.33%。提示GBV-C可能不是非甲~非戊型肝炎的主要致病因子,可能存在GBV-C健康携带者。 相似文献
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We present an interactive method for mesh segmentation that is inspired by the classical live‐wire interaction for image segmentation. The core contribution of the work is the definition and computation of wires on surfaces that are likely to lie at segment boundaries. We define wires as geodesics in a new tensor‐based anisotropic metric, which improves upon previous metrics in stability and feature‐awareness. We further introduce a simple but effective mesh embedding approach that allows geodesic paths in an anisotropic path to be computed efficiently using existing algorithms designed for Euclidean geodesics. Our tool is particularly suited for delineating segmentation boundaries that are aligned with features or curvature directions, and we demonstrate its use in creating artist‐guided segmentations. 相似文献
49.
Jiuxin Jiang Bo Zhu Peiling Wang Weiwu Chen Dongsheng Yan Hanrui Zhuang Yibing Cheng 《Journal of the American Ceramic Society》2005,88(4):950-953
The Pr α-sialon powders prepared by self-propagating high-temperature synthesis (SHS), consisting of 55 wt% Pr α-sialon and 45 wt% of β-sialon (abbreviated as α' and β'), were hot-pressed at 1800°C for 1 h. The results showed that Pr α' phase would transfer to β' with the appearance of JEM phase (Pr(Si6− z Al z )(N10− z O z )) after sintering, thus resulting in the increase of β' phase to 86 wt%. The addition of Y2 O3 into SHS-ed Pr α' powders as the starting materials restrains the transformation of α' to β' and prevents the formation of JEM phase as well. The nucleation mechanism of Pr α' grain during hot-pressing was investigated in terms of transmission electron microscope and energy-dispersive spectrometer analysis. Two nucleation modes of Pr α' grains were found, i.e., nucleating on the undissolved Pr α' grains and on the nuclei of (Pr, Y) α' grains precipitated from liquid phase. 相似文献
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