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101.
102.
PA Smanik KY Ryu KS Theil EL Mazzaferri SM Jhiang 《Canadian Metallurgical Quarterly》1997,138(8):3555-3558
The active iodide uptake of the thyroid gland in humans is mediated by the human sodium iodide symporter (hNIS). In this report, we show that hNIS expression was detected primarily in thyroid tissue, but also in breast, colon, and ovary tissues. Expression of hNIS is greatly reduced in thyroid tumors compared to normal thyroid tissue. Among tumor tissues, hNIS expression appears to be variable, consistent with the variable response to radioiodide treatment observed for thyroid carcinomas. The coding region of hNIS is interrupted by 14 introns, and the nucleotide sequence of each exon-intron junction is reported. Using this information, an alternatively spliced form of hNIS was identified. Finally, the chromosome location of the hNIS gene was mapped to chromosome 19p. 相似文献
103.
讨论了多重帐户问题在计算机网络管理中诸多弊端。提出以目录服务(Novell NDS)为基础,实现跨平台(NetWare、WindowsNT和Solaris)的帐刻统一管理的方案及详细实施实例。 相似文献
104.
跨孔电磁波CT法在勘查岩溶方面大有可为。在西南某电站坝基勘查中,成功地应用了跨孔电磁波CT法,分别在左坝肩和右坝肩中所探查的二对孔间,圈出了岩溶的发育范围。所提交的资料已得到钻探、平硐勘探资料、声波和数字摄像的据互相印证。为进一步施工提供了较好的指导作用。本次勘查使用的是最新型的JW—5Q型大功率仪器和新版的处理软件,并成功地使用高频穿透98m地层,是一次很成功的应用。 相似文献
105.
This paper proposes a new method to describe and identify a 3-D curved object for the purpose of validating a fabricated object to the design specification. Curved 3-D objects are, in general, difficult to represent and identify because they lack distinct properties such as edges, planes, or cylindrical surfaces which are the building blocks in representing objects. In this paper, the authors propose to use principal axes of a 3-D object to establish a reference for the representation. A method of obtaining an inertia matrix from a 3-D range image is developed. The unique set of principal axes is obtained from the inertia matrix of an object with an arbitrary 3-D position and orientation, and the object can be described uniquely on these principal axes. On the principal axes, an object is described by a set of features describing the shape of the object such as spine, section size, section orientation, and section contraction. The features are used for comparing two objects for the validation purpose. The authors also propose a direct measure of similarity between two objects as a mean-squared difference of radii. As an experiment, two 3-D object models are designed through a CAD package, and fabricated objects are compared with the designed models for validation purposes 相似文献
106.
介绍了为攀钢“501”滑动水口研制的专用液压驱动系统,对该系统的工作原理,性能特点,主要元件(设备)的选择原则等作了较为详细的说明介绍。 相似文献
107.
Sun Linzhi Luo Yi Zhang Yanan Sun Ping Qin Xinjie Gong ZhenbangPrecision Machinery Institute Shanghai University Shanghai China 《机械工程学报(英文版)》2002,15(4):303-307
An experimental bimorph piezoelectric element (PZT) actuator for small pipe robot is developed. The robot can move in φ20 mm pipe, and can carry a CCD camera for detecting cracks or fine holes on inner surface of pipe. The velocity of the robot can reach 17~22 mm/s for vertical pipe up/down, respectively. Moving principle and its performance characteristics are presented. 相似文献
108.
109.
DL Newton S Walbridge SM Mikulski W Ardelt K Shogen SJ Ackerman SM Rybak RJ Youle 《Canadian Metallurgical Quarterly》1994,14(2):538-544
Purkinje cell toxicity is one of the characteristic features of the Gordon phenomenon, a syndrome manifested by ataxia, muscular rigidity, paralysis, and tremor that may lead to death (Gordon, 1933). Two members of the RNase superfamily found in humans, EDN (eosinophil-derived neurotoxin) and ECP (eosinophil cationic protein), cause the Gordon phenomenon when injected intraventricularly into guinea pigs or rabbits. We have found that another member of the RNase superfamily, an antitumor protein called onconase, isolated from Rana pipiens oocytes and early embryos, will also cause the Gordon phenomenon when injected into the cerebrospinal fluid of guinea pigs at a dose similar to that of EDN (LD50, 3-4 micrograms). Neurologic abnormalities of onconase-treated animals were indistinguishable from those of EDN-treated animals, and histology showed dramatic Purkinje cell loss in the brains of onconase-treated animals. The neurotoxic activity of onconase correlates with ribonuclease activity. Onconase modified by iodoacetic acid to eliminate 70% and 98% of the ribonuclease activity of the native enzyme displays a similar decrease in ability to cause the Gordon phenomenon. In contrast, the homologous bovine pancreatic RNase A injected intraventricularly at a dose 5000 times greater than the LD50 dose of EDN or onconase is not toxic and does not cause the Gordon phenomenon. A comparison of the RNase activities of EDN, onconase, and bovine pancreatic RNase A using three pancreatic RNA substrates demonstrates that onconase is orders of magnitude less active enzymatically than EDN and RNase A. Thus, another member of the RNase superfamily in addition to EDN and ECP can cause the Gordon phenomenon.(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献
110.
The aims of this study were to examine a prototype battery operated wax-knife, assess the extent to which manufacturer's claims have been achieved and determine its potential for clinical use. The mean time required for the wax-knife to achieve an operating temperature of 150 degrees C was 20.2(+/-4.3) s. The mean operating temperature of the ceramic blade was 155.4(+/-3.9) degrees C, range 150 degrees C to 162 degrees C. The mean usage time following full battery recharge was 42 (+/-2) minutes. The wax-knife provided a direct heating tool which retained many of the characteristics of the traditional wax-knife and was suitable for use in the surgery and in domiciliary situations. 相似文献