A plane stress to plane strain functional technique to compute stress-intensity factors in three-dimensional problems

A functional technique to calculate stress-intensity factors for cracks intersecting or approaching free surfaces is presented. Results are compared to previous finite elements and alternating solutions. The comparison shows that use of a full plane strain formula could be questionable in three-dimensional problems where cracks approach or intersect free surfaces.     

Effect of vitamin E and beta carotene on the incidence of primary nonfatal myocardial infarction and fatal coronary heart disease

BACKGROUND: Oxidized low-density lipoprotein is involved in the pathogenesis of atherosclerosis. In epidemiological studies antioxidants have been inversely related with coronary heart disease. Findings from controlled trials are inconclusive. METHODS: We studied the primary preventive effect of vitamin E (alpha tocopherol) and beta carotene supplementation on major coronary events in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study, a controlled trial undertaken primarily to examine the effects of these agents on cancer. A total of 27 271 Finnish male smokers aged 50 to 69 years with no history of myocardial infarction were randomly assigned to receive vitamin E (50 mg), beta carotene (20 mg), both agents, or placebo daily for 5 to 8 years (median, 6.1 years). The end point was the first major coronary event, either nonfatal myocardial infarction (surviving at least 28 days; n = 1204) or fatal coronary heart disease (n = 907). RESULTS: The incidence of primary major coronary events decreased 4% (95% confidence interval, -12% to 4%) among recipients of vitamin E and increased 1% (95% confidence interval, -7% to 10%) among recipients of beta carotene compared with the respective nonrecipients. Neither agent affected the incidence of nonfatal myocardial infarction. Supplementation with vitamin E decreased the incidence of fatal coronary heart disease by 8% (95% confidence interval, -19% to 5%), but beta carotene had no effect on this end point. CONCLUSIONS: Supplementation with a small dose of vitamin E has only marginal effect on the incidence of fatal coronary heart disease in male smokers with no history of myocardial infarction, but no influence on nonfatal myocardial infarction. Supplementation with beta carotene has no primary preventive effect on major coronary events.     

Are frontal and parietal somatosensory evoked potentials functionally dissociated by changing stimulus rate?

The cortical somatosensory evoked potentials are known to be sensitive to relatively small changes in the stimulus repetition rate of the afferent nerve. However, conflicting reports exist as to whether frontally and parietally recorded potentials at a given latency show differential behaviors as a function of stimulus rate. Because such dissociations of frontal and parietal potentials can have significant implications for the SEP generation mechanisms, the present study was undertaken to further describe in detail these effects on frontal, central and parietal waveforms after median nerve stimulation. Increasing stimulus repetition rate from 1 Hz to 5 Hz had the following effects: (i) in 9 of 16 subjects, the frontal P20 diminished while parietal N20 clearly remained unaltered, (ii) the central P22 was reduced in all subjects, (iii) frontal N30 and parietal P27 were attenuated in all subjects, the average magnitude of the reductions being nearly equal for these deflections. The results support the view that changing stimulus rate can functionally dissociate frontal and parietal activity around 20 ms, indicating that several partially independent neural populations can contribute to the frontal P20. The results did not lend support for functional dissociation of frontal N30 from parietal P27.     

The Helsinki Heart Study: an 8.5-year safety and mortality follow-up

MT-PVLT-10 transgenic mice express the large T-antigen of polyomavirus under the control of the mouse metallothionein-1 promoter. The males of this transgenic line developed testicular tumor and seminal vesicle engorgement at advanced ages. A novel partial cDNA was identified which hybridized to a 2.6 kilobase mRNA. The expression of this mRNA increased approximately two- to fifteen-fold in immortalized cell lines derived from testicular tumors as compared to similar cell lines derived from pre-adenomatous testes. The in vivo pattern of expression for this cDNA as well as its expression in various primary cultures and established cell lines derived from testis of MT-PVLT-10 mice is presented. Overlapping cDNA clones from liver, testes, and brain cDNA libraries containing the entire coding region for this novel cDNA have been isolated and sequenced. The coding region of this gene comprises 1179 nucleotides and predicts a polypeptide of 393 amino acids (calculated molecular mass 44,318). Motif analysis of the amino acid sequence has revealed that it contains several hydrophobic alpha-helices characteristic of transmembrane proteins.     

Copy-move tampering detection using affine transformation property preservation on clustered keypoints

Recent advances in multimedia technologies have made imaging devices and image editing tools ubiquitous and affordable. Image editing done with malicious intent is called as image tampering or forgery. The most common forgery is the copy-move forgery which involves copying a part of an image and pasting it on some other part of the same image. There are many existing methods for such forgery detection, but most of them are sensitive to post-processing and do not detect multiple instances of forgeries in an image. In the proposed approach, affine transformation property preservation of clustered keypoints in the image is used, which includes the tests for collinearity and distance ratio preservation. Our method is also able to detect multiple copy-move forgeries within an image. The proposed method is tested against four image tampering detection datasets, and the results of our method are the best compared to the existing eight state-of-the-art methods in terms of accuracy.     

SAW diffraction using the thin-element decomposition method

We adapt the angular spectrum of plane waves (ASPW) decomposition to numerical simulations of the diffraction of surface-acoustic waves (SAWs) on anisotropic model substrate, such as YZ lithium niobate. We utilize the thin-element decomposition (TED) method, appropriately modified for an anisotropic substrate; we also introduce a novel "average-wavenumber" variation of this scheme; these are numerically found to be mutually consistent. We apply the TED method to simulate wave propagation both in infinite periodic structures of metallized gratings and also in finite gratings. We demonstrate that the ASPW provides a convenient and numerically fast tool for precise diffraction calculations in practical SAW devices which also display structural variations in the lateral direction, perpendicular to the principal direction of wave propagation. Additionally, we compare the present TED method to waveguide theory in an analysis of the role of SAW reflections from the electrodes.     

Multi-Parallel Adaptive Grasshopper Optimization Technique for Detecting Anonymous Attacks in Wireless Networks

Wireless Personal Communications - For a number of years, due to exponential increase in the demand for sustainable environment, suspicious activities have recently been identified as over-serious...     

CHOOSE: Towards a metamodel for enterprise architecture in small and medium-sized enterprises

Enterprise architecture (EA) is a coherent whole of principles, methods, and models that are used in the design and realization of an enterprise’s organizational structure, business processes, information systems, and IT infrastructure. Recent research indicates the need for EA in small and medium-sized enterprises (SMEs), important drivers of the economy, as they struggle with problems related to a lack of structure and overview of their business. However, existing EA frameworks are perceived as too complex and, to date, none of the EA approaches are sufficiently adapted to the SME context. Therefore, this paper presents the CHOOSE metamodel for EA in SMEs that was developed and evaluated through action research in an SME and further refined and validated through case study research in five other SMEs. This metamodel is based on the essential dimensions of EA frameworks and is kept simple so that it may be applied in an SME context. The final CHOOSE metamodel includes only four essential concepts (i.e. goal, actor, operation, object), one for each most frequently used EA focus. As an example, an extract is included from the specific model that was created for the SME used in our action research. Finally, the CHOOSE metamodel is evaluated according to the dimensions essential in EA and the requirements for EA in an SME context.