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41.
Marchand B Douek PC Robert P Corot C Roux JP Adeleine P Hernandez-Hoyos M Cremillieux Y Orkisz M Canet E 《Magma (New York, N.Y.)》2002,14(3):259-267
Purpose To investigate the relative role of high resolution (spatial or temporal) magnetic resonance angiography (MRA) sequence and
of contrast agent properties in the evaluation of high-degree arterial stenosis.
Methods We qualitatively and quantitatively studied both 50 and 95% (300 μm diameter) stenosis of a 6 mm arterial phantom with two
contrast agents (CA), Gd-DOTA (r1 =2.9 mM−1 s−1) versus P760 (r1 =25 mM−1 s−1) at several CA concentrations, including arterial peak concentration after injection of either a single or double dose of
CA, using either a high temporal (booster) or high spatial (HR) resolution 3D MRA sequences. Experimental data were then compared
to theoretical data.
Results With the 3D HR sequence, both visual and quantitative analysis were significantly better compared to the 3D booster sequence,
at each phantom diameter. Quantitative analysis was significantly improved by injection of a double versus a single dose of
each CA (Gd-DOTA or P760), primarily in high degree stenosis.
Conclusion Combined MRA spatial resolution and high CA efficiency are mandatory to correctly evaluate high degree stenosis. 相似文献
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44.
Marcela Boroski Ana Carolina de AguiarJoana Schuelter Boeing Eliza Mariane RottaCamila Leite Wibby Elton Guntendorfer BonaféNilson Evelázio de Souza Jesuí Vergílio Visentainer 《Food chemistry》2011
Five different pasta formulations were prepared using different concentrations of carrot leaf meal (CLM) and oregano leaf meal (OLM). One control formulation (wheat flour and semolina, 70:30 w/w) and four other formulations were prepared using the following amounts of leaf meals: 5% CLM and 5% OLM (I), 10% CLM (II), 10% OLM (III), and 10% CLM, 10% OLM (IV). The highest content of alpha-linolenic acid was found in formulations II and IV, which also had a reduced n-6/n-3 ratio, 3.6 (IV), when compared to the control, which was 19.8. All the samples enhanced with leaf meals showed antioxidant activity by the DPPH radical method; however, it was higher in formulation IV, which was the same observed for phenolic compounds. Pasta added with leaf meals lost more solubles, had shorter cooking time and a lower weight increase than the control pasta. All formulations had significant sensory acceptance. 相似文献
45.
Covalent attachment of functional protein to polymer surfaces: a novel one-step dry process.
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Christopher MacDonald Richard Morrow Anthony S Weiss Marcela M M Bilek 《Journal of the Royal Society Interface》2008,5(23):663-669
The attachment of bioactive protein to surfaces underpins the development of biosensors and diagnostic microarrays. We present a surface treatment using plasma immersion ion implantation (PIII) to create stable covalent binding sites for the attachment of functional soya-bean peroxidase (SBP). Fourier transform infrared spectra of the surfaces show that protein is retained on the surface after boiling in sodium dodecyl sulphate and sodium hydroxide, which is indicative of covalent attachment. The activity of SBP on the treated surfaces remains high in comparison with SBP attached to control surfaces over the course of 11 days. Surface plasmon resonance was used to show that the surface coverage of the attached protein is close to a monolayer. We describe the potential of the PIII treatment method to be used as a one-step dry process to create surfaces for large-scale protein micro- or nanopatterning. 相似文献
46.
Sergio P. Ferro R. Javier Principe Marcela B. Goldschmit 《Metallurgical and Materials Transactions B》2001,32(6):1185-1193
Mathematical models for the evaluation of residence time distribution (RTD) curves on a large variety of vessels are presented.
These models have been constructed by combination of different tanks or volumes. In order to obtain a good representation
of RTD curves, a new volume (called convection diffusion volume) is introduced. The convection-diffusion volume allows the
approximation of different experimental or numerical RTD curves with very simple models. An algorithm has been developed to
calculate the parameters of the models for any given set of RTD curve experimental points. Validation of the models is carried
out by comparison with experimental RTD curves taken from the literature and with a numerical RTD curve obtained by three-dimensional
simulation of the flow inside a tundish. 相似文献
47.
Phenolic composition and mouthfeel characteristics resulting from blending Chilean red wines
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48.
The distribution of clock signals throughout the nodes of a network is essential for several applications in control and communication with the phase-locked loop (PLL) being the component for electronic synchronization process. In systems with master–slave (MS) strategies, the PLLs are the slave nodes responsible for providing reliable clocks in all nodes of the network. As PLLs have nonlinear phase detection, double-frequency terms appear and filtering becomes necessary. Imperfections in filtering process cause oscillations around the synchronous state worsening the performance of the clock distribution process. The behavior of one-way master–slave (OWMS) clock distribution networks is studied and performances of first- and second-order filter processes are compared, concerning lock-in ranges and responses to perturbations of the synchronous state. 相似文献
49.
César Valderrama Xavier Gamisans Jose L Cortina Adriana Farrán F Xavier de las Heras 《Journal of chemical technology and biotechnology (Oxford, Oxfordshire : 1986)》2009,84(2):236-245
BACKGROUND: Sorption of polycyclic aromatic hydrocarbons (PAHs) on activated carbon and the Macronet polymeric sorbent MN200 was investigated to determine the effectiveness of each sorbent for removal of pollutants from aqueous solution and their possible use as sorbent materials for groundwater. Experiments were carried out to determine the loading capacities of a family of PAHs (acenaphthene, anthracene, fluoranthene, fluorene, naphthalene and pyrene). RESULTS: Activated carbon was the more effective sorbent, with maximum loadings of PAHs between 90 and 230 g kg?1, while MN200 resin showed values of 25–160 g kg?1. Loading isotherms based on the Langmuir, Freundlich and Redlich–Peterson models were determined. The hydrophobic character of the pollutants appeared as an important parameter related to the sorption process. Equilibrium and kinetic parameters were used to determine the retardation factors for each PAH. CONCLUSION: The calculated values for the simulation of barrier thickness using both sorbents, taking into account EU requirements for PAHs in groundwater effluent, were perfectly reasonable as a first estimate. The better kinetic properties of MN200 are evident in lower hydraulic residence times and consequently in a lower barrier thickness. Copyright © 2008 Society of Chemical Industry 相似文献
50.
Mauricio Osorio Marcela Carvajal Alejandra Vergara Estefania Butassi Susana Zacchino Carolina Mascayano Margarita Montoya Sophia Mejías Marcelo Cortez-San Martín Yesseny Vsquez-Martínez 《International journal of molecular sciences》2021,22(11)
Prenylated flavonoids are an important class of naturally occurring flavonoids with important biological activity, but their low abundance in nature limits their application in medicines. Here, we showed the hemisynthesis and the determination of various biological activities of seven prenylated flavonoids, named 7–13, with an emphasis on antimicrobial ones. Compounds 9, 11, and 12 showed inhibitory activity against human pathogenic fungi. Compounds 11, 12 (flavanones) and 13 (isoflavone) were the most active against clinical isolated Staphylococcus aureus MRSA, showing that structural requirements as prenylation at position C-6 or C-8 and OH at positions C-5, 7, and 4′ are key to the antibacterial activity. The combination of 11 or 12 with commercial antibiotics synergistically enhanced the antibacterial activity of vancomycin, ciprofloxacin, and methicillin in a factor of 10 to 100 times against drug-resistant bacteria. Compound 11 combined with ciprofloxacin was able to decrease the levels of ROS generated by ciprofloxacin. According to docking results of S enantiomer of 11 with ATP-binding cassette transporter showed the most favorable binding energy; however, more studies are needed to support this result. 相似文献