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71.
Virtual Reality - The intersection between sound and music computing and Virtual Reality (VR) has grown significantly over the past decades, amounting to an established area of research today.... 相似文献
72.
Felix M. Escalante Andres L. Jutinico Marco H. Terra Adriano A. G. Siqueira 《Asian journal of control》2023,25(4):2564-2576
The natural instability of an inverted pendulum and its dynamics richness, in terms of nonlinearity, provide a nice apparatus to reproduce behaviors of analogous systems. In this way, it is useful to perform benchmark tests for new control approaches developed. In this paper, we address the main inverted pendulum problems: pendulum stabilization, tracking, and catching swing-up control. We show how robust recursive, control and filtering, techniques improve the system performance. They are developed to solve stochastic problems based on deterministic approaches, in order to decrease the worst influence of uncertainties. Experimental results of the proposed robust approach provide robust stability and performance despite parametric uncertainties, disturbances, and noise effects. 相似文献
73.
Wurster Marco Michel Marius May Marvin Carl Kuhnle Andreas Stricker Nicole Lanza Gisela 《Journal of Intelligent Manufacturing》2022,33(2):575-591
Journal of Intelligent Manufacturing - Remanufacturing includes disassembly and reassembly of used products to save natural resources and reduce emissions. While assembly is widely understood in... 相似文献
74.
Paolini Emilio De Marinis Lorenzo Cococcioni Marco Valcarenghi Luca Maggiani Luca Andriolli Nicola 《Neural computing & applications》2022,34(18):15589-15601
Neural Computing and Applications - Photonics-based neural networks promise to outperform electronic counterparts, accelerating neural network computations while reducing power consumption and... 相似文献
75.
Iovine Andrea Lops Pasquale Narducci Fedelucio de Gemmis Marco Semeraro Giovanni 《Journal of Intelligent Information Systems》2022,58(2):337-362
Journal of Intelligent Information Systems - Conversational Recommender Systems have received widespread attention in both research and practice. They assist people in finding relevant and... 相似文献
76.
Davide Masato Marco Sorgato Giovanni Lucchetta 《Materials and Manufacturing Processes》2017,32(16):1823-1830
Centrifugal casting is a technology used for manufacturing hybrid rocket paraffin grains. This technology helps avoiding voids formation inside the solid paraffin as it cools. Voids are formed because of air bubbles being entrapped while pouring and because the liquid wax shrinks by 17–19% upon cooling. In this work, the centrifugal casting process for the manufacturing of paraffin cylinders was prototyped at two different scales considering critical casting issues. The effects of process parameters (rotational speed, melt temperature, and flow rate) on the tensile properties of the manufactured grains were analyzed. The results of the optimization conducted at the lower scale (2.5?kg) were up scaled to manufacture 25?kg grains. The resulting mechanical properties complied with the design specifications, and they were better than those characterized from the gravity cast wax. A numerical model of growth and dissolution of bubbles during the process was then developed to predict the quality of the castings. The numerical results showed how increasing the mold rotational speed up to 1800?rpm reduced the removal time. However, compared to grains solidification time, the predicted removal times were much shorter, proving the advantage of centrifugal casting in counteracting voids formation. 相似文献
77.
Depalo Nicoletta Iacobazzi Rosa Maria Valente Gianpiero Arduino Ilaria Villa Silvia Canepa Fabio Laquintana Valentino Fanizza Elisabetta Striccoli Marinella Cutrignelli Annalisa Lopedota Angela Porcelli Letizia Azzariti Amalia Franco Massimo Curri Maria Lucia Denora Nunzio 《Nano Research》2017,10(7):2431-2448
Currently,sorafenib is the only systemic therapy capable of increasing overall survival of hepatocellular carcinoma patients.Unfortunately,its side effects,particularly its overall toxicity,limit the therapeutic response that can be achieved.Superparamagnetic iron oxide nanoparticles (SPIONs) are very attractive for drug delivery because they can be targeted to specific sites in the body through application of a magnetic field,thus improving intratumoral accumulation and reducing adverse effects.Here,nanoformulations based on polyethylene glycol modified phospholipid micelles,loaded with both SPIONs and sorafenib,were successfully prepared and thoroughly investigated by complementary techniques.This nanovector system provided effective drug delivery,had an average hydrodynamic diameter of about 125 nm,had good stability in aqueous medium,and allowed controlled drug loading.Magnetic analysis allowed accurate determination of the amount of SPIONs embedded in each micelle.An in vitro system was designed to test whether the SPION micelles can be efficiently held using a magnetic field under typical flow conditions found in the human liver.Human hepatocellular carcinoma (HepG2) cells were selected as an in vitro system to evaluate tumor cell targeting efficacy of the superparamagnetic micelles loaded with sorafenib.These experiments demonstrated that this delivery platform is able to enhance sorafenib's antitumor effectiveness by magnetic targeting.The magnetic nanovectors described here represent promising candidates for targeting specific hepatic tumor sites,where selective release of sorafenib can improve its efficacy and safety profile. 相似文献
78.
In recent years, X-ray screening systems have been used to safeguard environments in which access control is of paramount importance. Security checkpoints have been placed at the entrances to many public places to detect prohibited items such as handguns and explosives. Human operators complete these tasks because automated recognition in baggage inspection is far from perfect. Research and development on X-ray testing is, however, ongoing into new approaches that can be used to aid human operators. This paper attempts to make a contribution to the field of object recognition by proposing a new approach called Adaptive Sparse Representation (XASR+). It consists of two stages: learning and testing. In the learning stage, for each object of training dataset, several patches are extracted from its X-ray images in order to construct representative dictionaries. A stop-list is used to remove very common words of the dictionaries. In the testing stage, test patches of the test image are extracted, and for each test patch a dictionary is built concatenating the ‘best’ representative dictionary of each object. Using this adapted dictionary, each test patch is classified following the Sparse Representation Classification methodology. Finally, the test image is classified by patch voting. Thus, our approach is able to deal with less constrained conditions including some contrast variability, pose, intra-class variability, size of the image and focal distance. We tested the effectiveness of our method for the detection of four different objects. In our experiments, the recognition rate was more than 97 % in each class, and more than 94 % if the object is occluded less than 15 %. Results show that XASR+ deals well with unconstrained conditions, outperforming various representative methods in the literature. 相似文献
79.
In this article, a new population-based algorithm for real-parameter global optimization is presented, which is denoted as self-organizing centroids optimization (SOC-opt). The proposed method uses a stochastic approach which is based on the sequential learning paradigm for self-organizing maps (SOMs). A modified version of the SOM is proposed where each cell contains an individual, which performs a search for a locally optimal solution and it is affected by the search for a global optimum. The movement of the individuals in the search space is based on a discrete-time dynamic filter, and various choices of this filter are possible to obtain different dynamics of the centroids. In this way, a general framework is defined where well-known algorithms represent a particular case. The proposed algorithm is validated through a set of problems, which include non-separable problems, and compared with state-of-the-art algorithms for global optimization. 相似文献
80.
Cássia A. Glasser Marta M. D. C. Vila Júlio C. Pereira Marco V. Chaud José M. Oliveira Júnior Matthieu Tubino 《Drug development and industrial pharmacy》2016,42(12):1990-2000
The aqueous-core enclosed in lipid nanoballoons integrating multiple emulsions of the type water-in-oil-in-water mimic, at least in theory, the environment within viable cells, thus being suitable for housing hydrophilic protein entities such as bioactive proteins, peptides and bacteriophage particles. This study reports a complete physicochemical characterization of optimized biomimetic aqueous-core lipid nanoballoons housing hydrophilic (BSA) protein entities, evolved from a statistical 23×31 factorial design study (three variables at two levels and one variable at three levels) that was the subject of the first paper of a series of three, aiming at complete stabilization of the three-dimensional structure of protein entities attempted via housing the said molecular entities within biomimetic aqueous-core lipid nanoballoons integrating a multiple (W/O/W) emulsion. The statistical factorial design followed led to the production of an optimum W/O/W multiple emulsion possessing quite homogeneous particles with an average hydrodynamic size of (186.2?±?2.6) nm and average Zeta potential of (?36.5?±?0.9) mV, and exhibiting a polydispersity index of 0.206?±?0.014. Additionally, the results obtained for the diffusion coefficient of the lipid nanoballoons integrating the optimized W/O/W multiple emulsion were comparable and of the same order of magnitude (10?12 m2 s?1) as those published by other authors since, typically, diffusion coefficients for molecules range from 10?10 to 10?7 m2 s?1, but diffusion coefficients for nanoparticles are typically of the order of magnitude of 10?12 m2 s?1. 相似文献