Sub-micrometer particulate air pollution and cardiovascular mortality in Beijing, China

Background

While the link between particulate matter and cardiovascular mortality is well established, it is not fully investigated and understood which properties of the aerosol might be responsible for the health effects, especially in polluted mega-city areas.

Objectives

Our goal was to explore the association between daily cardiovascular mortality and different particle metrics in the sub-micrometer range in Beijing, China.

Methods

We obtained daily counts of cause-specific cardiovascular deaths in the Beijing urban area for the period March 2004 to August 2005. Concurrently, continuous measurements of particle number size distributions were performed. Particle number concentrations (NC) between 0.003 μm and 0.8 μm were converted to particle mass and surface area concentrations assuming spherical particles. Semi-parametric Poisson regression models adjusting for trend, seasonality, day of the week, and meteorology were used to estimate immediate, delayed and cumulative particle effects. Additionally, effect modification by air mass origin was investigated.

Results

We observed associations between daily cardiovascular mortality and particle NC for a 2-days delay. Moreover, nearly all particle metrics showed 2-days delayed associations with ischemic heart disease mortality. The strongest association was found for particle NC in the size range 0.03-0.1 μm (7.1% increase in daily mortality with a 95%-confidence interval of 2.9%-11.5%, per an increase of 6250 particles/cm³). Results for surface and mass concentrations with a lag of two days indicated effect modification by air mass origin, whereas effects of particle NC were not modified.

Conclusions

Results show an elevated risk of cardiovascular mortality in Beijing from short-term exposure to particulate air pollution in the sub-micrometer range. Results also indicate that locally produced smaller particles and regionally transported particles may exhibit different effects in Beijing.     

Innovations in Large-Scale Supported Distance Teaching: Transformation for the Internet,Not Just Translation

This paper reports on large-scale trials of Internet-based university-level distance teaching. The use of technology, and more specifically the Internet, has been an important advance for distance education. However, simply translating material from familiar media into electronic form is rarely productive—and is certainly inadequate for supported distance education, which aims to engage the student in a “community of learning.” The value Internet technology brings to distance education lies not in direct translation from other media but in transformation of support mechanisms to exploit its potential range. The paper addresses how instruction and support functions can be served and potentially enhanced by an Internet-based structure. It considers which changes in culture help to preserve or improve teaching quality while adapting to screen-based and often asynchronous interactions. It discusses our trials of mechanisms for interactions among students and tutors; assignment marking using an electronic marking tool; electronic assignment handling; synchronous and asynchronous Internet-based problem sessions; and automatic student registration. The paper summarizes qualitative and quantitative findings of an extensive evaluation involving several hundred students over three courses and considering learning, student experience, assignment marking, problem sessions, scalability, and integration into existing administrative structures. It highlights both costs and gains of using the Internet to transform the distance learning environment for those associated with it: students, tutors, administrators, and institutions.     

Less is more: Meta-analyses of sensitivity and attachment interventions in early childhood.

Is early preventive intervention effective in enhancing parental sensitivity and infant attachment security, and if so, what type of intervention is most successful? Seventy studies were traced, producing 88 intervention effects on sensitivity (n=7,636) and/or attachment (n=1,503). Randomized interventions appeared rather effective in changing insensitive parenting (d=0.33) and infant attachment insecurity (d=0.20). The most effective interventions used a moderate number of sessions and a clear-cut behavioral focus in families with, as well as without, multiple problems. Interventions that were more effective in enhancing parental sensitivity were also more effective in enhancing attachment security, which supports the notion of a causal role of sensitivity in shaping attachment. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Investigation of Heaving at Holloman Air Force Base, New Mexico

Heaving of pavements and a building foundation became progressively worse on a project at Holloman Air Force Base (AFB), N.M. The cause of the heaving was identified as sulfate attack on recycled concrete used as fill and base course below the buildings and pavements. This recycled concrete came from sulfate-resistant airfield Portland concrete pavement that had existed for decades at Holloman AFB without distress. However, severe sulfate exposure conditions, ready availability of water, the more permeable nature of the crushed recycled concrete, less common thaumasite attack, possible soil contamination as a secondary source of alumina, or some combination of these factors allowed sulfate attack to develop in the recycled material even though it had not in the original concrete pavement.     

On the conditions for success of sklansky''s convex hull algorithm

The convex hull algorithm for simple polygons, due to Sklansky, fails in some cases, but its extreme simplicity, compared to the later algorithms, revived an interest in this algorithm. A sufficient condition for its success was given recently by Toussaint and Avis. They have proved that the algorithm works for polygons known as weakly externally visible polygons.

In this paper a new notion called external left visibility is introduced and it is shown that this is a necessary and sufficient condition for the success of Sklansky's algorithm. Moreover, algorithms testing simple polygons for external left visibility and weak external visibility are given.     

Modification of polyvinylchloride in solution or suspension by nucleophilic substitution

Nucleophilic displacement of chlorine from polyvinylchloride (PVC) suspended either in water or in solution can be achieved using a nucleophile such as a sodium thiolate (R? S^?, Na⁺). The nucleophilicity of the salt increases if an ether linkage exists in a β position to the thiol group [R? O? (CH₂)₂? S^?, Na⁺]. Addition of a solvent such as cyclohexanone (which is a good solvent for PVC) to the slurry increases substantially the degree of substitution. Elemental analysis shows that every chlorine displaced from the polymer is replaced by a thiolate group; thus almost no dehydrochlorination occurs. It is possible to obtain by this method a grafted polymer in which 33% of the chlorine atoms are replaced by the β-ether thiolate group. The resulting polymer behaves like an internally plasticized PVC. The higher the degree of substitution of chlorine, the greater the flexibility of the grafted polymer is. Other compounds, such as lauryl thiolate and diethyl dithiocarbamate, also were used as nucleophiles, the latter one resulting in a brittle crosslinked polymer whenever sulfur was above 2%. Grafting of polytetrahydrofuran from PVC also was achieved using tetrahydrofuran as solvent and silver-perchlorate as catalyst. The resulting flexible grafted polymer is believed to consist of longer chains of polytetrahydrofuran grafted from few displaced chlorine atoms along the PVC chain.     

An observational study of maternal models.

Observed 35 mothers in interaction with their 19-mo old infants in seminaturalistic settings. Mothers' modeling techniques, their reinforcements for imitation, and children's imitations were recorded. Imitation and reinforcement for imitation were complexly related; for some children maternal reinforcement appeared to control the amount of imitation, but equally prominent were patterns in which reciprocal or interactive mother-child influences were in evidence. Characteristics of the mother, other than reinforcement of imitation, were positively associated with the child's imitation, particularly the amount of variation and the enthusiasm in the mother's modeling. Interpretations of findings in a seminaturalistic setting and findings from the laboratory are discussed with regard to methodological issues and theories relating to imitative learning. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Obese people who seek treatment have different characteristics than those who do not seek treatment.

A group of obese people who had not sought treatment; an obese group who had sought treatment in a professional, hospital-based program; and normal-weight controls (N?=?547) were compared in regard to level of psychopathology, binge eating, and negative emotional eating. Because the groups differed significantly on several demographic variables, 3 demographically matched groups were created and compared (n?=?177, 59 per group). In the matched subgroups, obese people who had sought treatment reported greater psychopathology and more binge eating than did normal-weight controls or those who had not sought treatment. Both obese groups (including those who had not sought treatment) endorsed more symptoms of distress, negative emotional eating, overeating, difficulty resisting temptation, and less exercise than did normal-weight controls. (PsycINFO Database Record (c) 2010 APA, all rights reserved)