Frequency and etiology of calf losses and calf diseases before weaning in cow-calf farms. II. Microbiological and parasitological diagnoses in diarrheic calves]

Diarrhea is the most frequently diagnosed disease in Swiss cow-calf farms. During an longitudinal study conducted in 105 cow-calf farms in Switzerland in 1993-95, blood and fecal samples were collected from diarrheic calves and from calves that died because of diarrhea. Campylobacter spp. were detected in 42%, E. coli (VTEC) in 32%, rotavirus in 33%, coronavirus in 13%, coccidia in 43% and helminths in 8% of the cases. In some samples Yersinia pseudotuberculosis were isolated. The BVD-virus antigen was not detected in any of the calves examined. In most cases concurrent infection with several enteropathogens was diagnosed. Specific causes of diarrhea were therefore difficult to establish. The bacteriological findings of this study have implication for food safety: VTEC, Campylobacter spp. Yersinia spp. and cryptosporidia are considered as potential causes on zoonoses.     

Topology of the principal EEG elements of sleep analyzed by analogue filters

In order to compare the venodilation effect of morphine in normal individuals (22) with that in patients (13) with heart failure morphine sulfate (0.1 mg/kg) was administered to 13 patients with mild pulmonary edema. After morphine congestive symptoms improved and venodilation was induced as determined by two independent techniques: venous pressure fell 10.2 mm Hg by the isolated hand technique and the venous volume of the forearm increased by 0.48 cc/100 ml, measured by equilibration technique. Neither finding differed from those in normal individuals. Reflex venoconstriction noted on the taking of a single deep breath was unaffected by morphine administration and was similar to that observed in normal subjects. Since the drug morphine sulfate does not cause a major pooling of blood in the limbs, the favorable effect of narcotics in patients with pulmonary edema must be caused by other mechanisms such as splanchnic pooling, afterload reduction or reduced breathing effort.     

Identification of a novel antigenic structure of the human receptor for interleukin-6 involved in the interaction with the glycoprotein 130 chain

PURPOSE: To evaluate the diagnostic accuracy of positron emission tomography (PET) with administration of 2-deoxy-2-[fluorine-18]fluoro-D-glucose (FDG) relative to that of magnetic resonance (MR) imaging and/or computed tomography (CT) in recurrent head and neck cancers. MATERIALS AND METHODS: Twelve adult patients (mean age, 63 years) with previously treated head and neck cancers and clinical suspicion of recurrence underwent FDG PET and MR imaging and/or CT. All images were blindly and independently interpreted without histopathologic findings (obtained within 1 week of imaging). The level of confidence in image interpretation was graded by using a five-point rating system (0 = definitely no recurrence to 4 = definite recurrence). RESULTS: Recurrence was confirmed in eight patients. With a rating of 4 as a positive finding, FDG PET yielded a sensitivity and specificity of 88% (seven of eight) and 100% (four of four), respectively; MR imaging and/or CT, 25% (two of eight) and 75% (three of four), respectively. Receiver-operating characteristic analysis showed significantly better diagnostic accuracy with FDG PET than with MR imaging and/or CT (area under curve = 0.96 vs 0.55, P < .03). CONCLUSION: These data indicate that PET metabolic imaging, as compared with anatomic methods, has improved diagnostic accuracy for recurrent head and neck cancer.     

Facteurs associés aux problèmes de comportement intériorisés et extériorisés chez des adolescentes agressées sexuellement.

The present study investigated the associated factors of internalising and externalising behaviour problems among sexually abused adolescents. One hundred fifty-eight female adolescent victims of sexual abuse, aged between 13 and 17 years, were recruited. Participants completed a battery of questionnaires measuring cognitive distortions, coping strategies, empowerment, behaviour problems, perception of their relationship with their mother and father, maternal support, characteristics of the sexual abuse as well as other forms of violence experienced. Results show that interpersonal distrust and general self-attributions of blame are two factors associated with both internalising and externalising behaviour problems. In addition, the mother/daughter relationship is associated with externalising behaviour problems. These results partially support Spaccarelli's model. They also highlight the important role of cognitive distortions, particularly general self-attributions of blame and interpersonal distrust, which may be targeted in treatments that are aimed at reducing behavioural problems. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Assessing the public health risk of microbial intrusion events in distribution systems: conceptual model, available data, and challenges

Low and negative pressure events in drinking water distribution systems have the potential to result in intrusion of pathogenic microorganisms if an external source of contamination is present (e.g., nearby leaking sewer main) and there is a pathway for contaminant entry (e.g., leaks in drinking water main). While the public health risk associated with such events is not well understood, quantitative microbial risk assessment can be used to estimate such risk. A conceptual model is provided and the state of knowledge, current assumptions, and challenges associated with the conceptual model parameters are presented. This review provides a characterization of the causes, magnitudes, durations and frequencies of low/negative pressure events; pathways for pathogen entry; pathogen occurrence in external sources of contamination; volumes of water that may enter through the different pathways; fate and transport of pathogens from the pathways of entry to customer taps; pathogen exposure to populations consuming the drinking water; and risk associated with pathogen exposure.     

Geomorphological methods to characterise wetlands at the scale of the Seine watershed

Based on easily available morphological data within the Seine river watershed (76750 km(2)), two approaches were used for wetland delineation and characterisation. Their common assumption is that geomorphology largely governs the spatial distribution of wetlands, because it determines topography and the nature of deposits, thus water pathways and residence times. The first approach relies on the topographic index introduced by Beven and Kirkby [Beven KJ, Kirkby MJ. A physically based, variable contributing area model of basin hydrology. Hydrol Sci Bull 1979; 24: 43-69.], that has been widely used to characterise saturated areas in small catchments. We mapped this index for the Seine watershed using a 100 m resolution DEM typical of DEMs easily available at this scale. The second approach relies on a geomorphological classification of river corridors which was specifically developed for the Seine basin. It is based on genetic concepts, and defines 13 types of river corridors as a function of the geometry of the river bed with respect to bedrock (incised, aggraded, encased, stable), the nature of alluvial fills, and the small scale morphology in the corridors. We used geological, hydrogeological and topographical maps of the Seine basin to delineate the river corridors and characterise the type of all the comprising streams with 2 km resolution. Two cartographic sources that were not exploited by the above methods were used to assess their performances. The wetlands depicted on 1:25000 topographic maps cover 2% of the Seine basin but are limited. The waterlogged soils from two 1:50000 pedologic maps are more reliable, but these maps only cover 5% of the watershed. In the river corridors, most wetlands fall in the encased and aggraded subsystems of the geomorphological classification, where the mean of the topographic index is significantly higher than in the other subsystems. High values of the topographic index are good general indicators of wetlands, even when calculated from a 100-m DEM. The agreement between the two studied methods confirms that geomorphology is the major driving factor for wetland distribution, even in a sedimentary basin with a strong influence of aquifers on hydrology. These complementary methods provide a powerful tool to complement the gaps of classical wetland databases at the scale of large watersheds.     

Influence of built environment on pedestrian's crossing decision

The objective of this experimental study is to identify the differentiation made by pedestrians, in their crossing decision, between various urban environments, notably in terms of perception of walking pleasantness and safety. This experiment further aims to identify the environmental features that pedestrians take into account and the inferences they develop and use to explain their road crossing decision. Sets of photographs presenting five different environments (city center, inner suburbs, public housing in the outskirts, commercial zone in the outskirts and countryside) were presented to 77 participants divided up into three age groups (pre-adolescents, young and middle adults). Their decision to cross or not, their perception of pleasantness and safety, and the elements they take into account to make a decision were collected for each environment presented. The quantitative results show the pedestrians’ perceptions of the pleasantness and safety of public spaces, in terms of walking, largely vary with urban environments. Moreover, the crossing decision significantly varies according to the environment. Pedestrians were significantly more inclined to take the decision to cross in city center than in the other sites presented. The qualitative analysis of the interviews shows that the presence and function of the buildings, the quality of the sidewalks and the marked parking spaces are key factors to explain their crossing decision, by enabling them to infer the density of pedestrians and traffic and the vehicle speed.     

Enriching our theoretical repertoire: the role of evolutionary psychology in technology acceptance

Information systems (IS) research has drawn heavily on social and cognitive psychology to explain technology adoption. Indeed, the many variations of the technology acceptance model all share these same theoretical foundations. Focusing exclusively on the socio-cognitive lens can lead to overlooking enhanced explanations of technology acceptance, such that new theoretical perspectives may be warranted. In this qualitative grounded theory study, we discovered how the lens of evolutionary psychology, as embodied in the Four-Drive model, was helpful in understanding technology acceptance across three organizational sites. We contend that evolutionary psychology is an important addition to the theoretical repertoire of IS researchers, and propose including ‘evolved psychological mechanisms’ within traditional models of technology acceptance.     

Coverage-biased random exploration of large models and application to testing

This paper presents several randomised algorithms for generating paths in large models according to a given coverage criterion. Using methods for counting combinatorial structures, these algorithms can efficiently explore very large models, based on a graphical representation by an automaton or by a product of several automata. This new approach can be applied to random exploration in order to optimise path coverage and can be generalised to take into account other coverage criteria, via the definition of a notion of randomised coverage satisfaction. Our main contributions are a method for drawing paths uniformly at random in composed models, i.e. models that are given as products of automata, first without and then with synchronisation; a new efficient approach to draw paths at random taking into account some other coverage criterion. Experimental results show promising agreement with theoretical predictions and significant improvement over previous randomised approaches. This work opens new perspectives for future studies of statistical testing and model checking, mainly to fight the combinatorial explosion problem.