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61.
Izumi Kita Tomohiro Shibata Yuki Kamiya Daishi Kato Kazuo Kunieda Keiji Yamada Kazushi Ikeda 《Artificial Life and Robotics》2009,14(3):375-378
To increase the productivity of knowledge workers, it is necessary to manage their organization so that they are motivated
to collaborate with each other for their synergy. However, it is difficult for managers to grasp the explicit interactions
of workers in the organization all the time. Owing to advanced communications technology, and the reduced size and improved
capabilities of computers, we are able to record group behaviors as logging data in the office. The aim of this study is to
extract features of group behavior from long-range office-logging data. We apply principal component analysis to the data
matrix whose element is the mean travel velocity calculated from an individual’s trajectory per day. The results demonstrate
the feasibility of our approach, since nontrivial informative group features can be extracted. 相似文献
62.
Atsushi Satsuma Hironaka Kanbe Kannan Srinivasan Shin-ich Komai Yuichi Kamiya Tadashi Hattori 《Microporous and mesoporous materials》2008,110(2-3):528-533
Nano-sized interlayer space of lamellar vanadyl benzylphosphate was controlled by water content in starting solution. Depending on the water content, three types of lamellar vanadyl benzylphosphate having basal spacings of 1.4 nm, 1.9 nm and 2.3 nm were obtained. It was suggested that the difference in the concentrations of benzyl and hydroxyl groups in the interlayer leads to the variation of the interlayer space. 相似文献
63.
Raynoo Thanan Shinji Oikawa Yusuke Hiraku Shiho Ohnishi Ning Ma Somchai Pinlaor Puangrat Yongvanit Shosuke Kawanishi Mariko Murata 《International journal of molecular sciences》2015,16(1):193-217
Reactive oxygen and nitrogen species have been implicated in diverse pathophysiological conditions, including inflammation, neurodegenerative diseases and cancer. Accumulating evidence indicates that oxidative damage to biomolecules including lipids, proteins and DNA, contributes to these diseases. Previous studies suggest roles of lipid peroxidation and oxysterols in the development of neurodegenerative diseases and inflammation-related cancer. Our recent studies identifying and characterizing carbonylated proteins reveal oxidative damage to heat shock proteins in neurodegenerative disease models and inflammation-related cancer, suggesting dysfunction in their antioxidative properties. In neurodegenerative diseases, DNA damage may not only play a role in the induction of apoptosis, but also may inhibit cellular division via telomere shortening. Immunohistochemical analyses showed co-localization of oxidative/nitrative DNA lesions and stemness markers in the cells of inflammation-related cancers. Here, we review oxidative stress and its significant roles in neurodegenerative diseases and cancer. 相似文献
64.
Dr. Naoki Umezawa Yuhei Horai Dr. Yuki Imamura Makoto Kawakubo Mariko Nakahira Dr. Nobuki Kato Akira Muramatsu Prof. Dr. Yuko Yoshikawa Prof. Dr. Kenichi Yoshikawa Prof. Dr. Tsunehiko Higuchi 《Chembiochem : a European journal of chemical biology》2015,16(12):1811-1819
A versatile solid‐phase approach based on peptide chemistry was used to construct four classes of structurally diverse polyamines with modified backbones: linear, partially constrained, branched, and cyclic. Their effects on DNA duplex stability and structure were examined. The polyamines showed distinct activities, thus highlighting the importance of polyamine backbone structure. Interestingly, the rank order of polyamine ability for DNA compaction was different to that for their effects on circular dichroism and melting temperature, thus indicating that these polyamines have distinct effects on secondary and higher‐order structures of DNA. 相似文献
65.
GJ Bishop T Nomura T Yokota K Harrison T Noguchi S Fujioka S Takatsuto JD Jones Y Kamiya 《Canadian Metallurgical Quarterly》1999,96(4):1761-1766
Brassinosteroids (BRs) are steroidal plant hormones essential for normal plant growth and development. Mutants in the biosynthesis or perception of BRs are usually dwarf. The tomato Dwarf gene (D), which was predicted to encode a cytochrome P450 enzyme (P450) with homology to other P450s involved in BR biosynthesis, was cloned previously. Here, we show that DWARF catalyses the C-6 oxidation of 6-deoxocastasterone (6-deoxoCS) to castasterone (CS), the immediate precursor of brassinolide. To do this, we first confirmed that the D cDNA complemented the mutant light- and dark-grown phenotypes of the extreme dwarf (dx) allele of tomato. To identify a substrate for the DWARF enzyme, exogenous application of BR intermediates to dx plants was carried out. C-6 oxoBR intermediates enhanced hypocotyl elongation whereas the C-6 deoxoBR, 6-deoxoCS, had little effect. Quantitative analysis of endogenous BR levels in tomato showed mainly the presence of 6-deoxoBRs. Furthermore, dx plants were found to lack CS and had a high level of 6-deoxoCS in comparison to D plants that had CS and a lower level of 6-deoxoCS. Confirmation that DWARF catalyzed the C-6 oxidation of 6-deoxoCS to CS was obtained by functional expression of DWARF in yeast. In these experiments, the intermediate 6alpha-hydroxycastasterone was identified, indicating that DWARF catalyzes two steps in BR biosynthesis. These data show that DWARF is involved in the C-6 oxidation in BR biosynthesis. 相似文献
66.
Masayoshi Kamiya Hiroaki Ikeda Shigenobu Shinohara 《International Journal of Communication Systems》2001,14(5):477-485
This paper describes a low‐cost version of a full‐duplex optical fibre analogue/digital data transmission link whose practical implementation is simplified by using a pair of laser diodes, each having a built‐in photodiode for monitoring the laser output power, and its application to vibration test data transmission. The transmission link sends digital data of up to 9600 bps in one direction, and analogue data of DC to 100 kHz and image data specified by an NTSC colour video signal in the opposite direction, all at the same time through one GI optical fibre. Being simple in configuration and stable against noise, this type of link has a variety of applications within factory, home and offices. Copyright © 2001 John Wiley & Sons, Ltd. 相似文献
67.
Mariko Suzuki Tomio Ono Naoshi Sakuma Tadashi Sakai 《Diamond and Related Materials》2009,18(10):1274-1277
Temperature-dependent emission current–voltage measurements were carried out for nitrogen (N)-doped nanocrystalline diamond (NCD) films grown on n-type Si substrates by microwave plasma-assisted chemical vapor deposition (MP-CVD). Low threshold temperature (~ 260 °C) and low threshold electric field (~ 5 × 10− 5 V/µm) were observed. Both the temperature dependence and the electric field dependence have shown that the obtained emission current was based on electron thermionic emission from N-doped NCD films. We have also studied the relation between nitrogen concentration and the saturation emission current. The saturation current obtained was as high as 1.4 mA at 5.6 × 10− 3 V/µm at 670 °C when the nitrogen concentration was 2.4 × 1020 cm− 3. Low value of effective work function (1.99 eV) and relatively high value of Richardson constant (~ 70) were estimated by well fitting to Richardson–Dushman equation. The results of smaller φ and larger A′ suggest that N-doped NCD has great possibility of being a highly efficient thermionic emitter material. 相似文献
68.
H. Sato K. Fukutani W. Futako T. Kamiya C. M. Fortmann I. Shimizu 《Solar Energy Materials & Solar Cells》2001,66(1-4)
Narrow band gap (1.5 eV) hydrogenated amorphous silicon (a-Si:H) were fabricated by a chemical annealing technique using noble gases (Ar, He, Ne). Although hydrogen content in the film was reduced to 1 atm% and band gap was decreased to 1.52 eV, high photoconductivity and large mobility–lifetime products were maintained and no marked changes in the short-range structure was found. Using these narrow band gap a-Si:H for photoactive layer in n-i-p solar cells, reasonable photovoltaic performances were obtained, i.e., open-circuit voltage of 0.71 V and fill factor of 57%. Also enhanced red response was observed with the 1.58 eV band gap i-layer solar cell prepared on textured substrate. 相似文献
69.
70.
By an immunomagnetic-bead (IMB) separation technique, isolation of Helicobacter pylori from gastrointestinal and fecal samples of gnotobiotic mice infected with the microorganism was tried. The isolation rate of H. pylori from stomach samples after IMB separation was not higher than that of direct culture of the samples. After IMB separation of feces, H. pylori was detectable by PCR, although H. pylori was not culturable. 相似文献