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21.
“Global Interoperability Using Semantics, Standards, Science and Technology” is a concept that is predicated on the assumption that the semantic integration, frameworks and standards that support information exchange, and advances in science and technology can enable information-systems interoperability for many diverse users. This paper recommends technologies and approaches for enabling interoperability across a wide spectrum of political, geographical, and organizational levels, e.g. coalition, federal, state, tribal, regional, non government, and private. These recommendations represent steps toward the goal of the Semantic Web, where computers understand information on web sites through knowledge representations, agents, and ontologies. 相似文献
22.
This article presents a method for classifying color points for automotive applications in the Hue Saturation Intensity (HSI)
Space based on the distances between their projections onto the SI plane. Firstly the HSI Space is analyzed in detail. Secondly
the projection of image points from a typical automotive scene onto the SI plane is shown. The minimal classes relevant for
driver assistance applications are derived. The requirements for the classification of the points into those classes are obtained.
Several weighting functions are proposed and a fast form of an euclidean metric is investigated in detail. In order to improve
the sensitivity of the weighting function, dynamic coefficients are introduced. It is shown how to compute them automatically
in order to get optimal results for the classification. Finally some results of applying the metric to the sample images are
shown and the conclusions are drawn.
Calin Rotaru is a PhD candidate at the Department of Computer Science, University of Hamburg, Germany. His PhD work focuses on the topic color machine vision for driver assistance systems and is supported by Volkswagen AG, Group Research Electronics. He graduated (2002) with the topic “Stereo Camera Based Object Recognition” for Driver Assistance Systems from the Faculty of Automation and Computer Science of the Technical University of Cluj-Napoca, Romania. His research interests include color machine vision, smart vision systems, multisensorial data fusion and vision in driver assistance systems. Thorsten Graf received the diploma (M.Sc.) degree in computer science and the Ph.D. degree (his thesis was on “Flexible Object Recognition Based on Invariant Theory and Agent Technology”) from the University of Bielefeld, Bielefeld, Germany, in 1997 and 2000, respectively. In 1997 he became a Member of the “Task Oriented Communication” graduate program, University of Bielefeld, funded by the German research foundation DFG. In June 2001 he joined Volkswagen Group Research, Wolfsburg, Germany. Since then, he has worked on different projects in the area of driver assistance systems as a Researcher and Project Leader. He is the author or coauthor of more than 40 publications and owns several patents. His research interests include image processing and analysis dedicated to advanced comfort/safety automotive applications. Dr. Jianwei Zhang is full professor and director of the Institute of Technical Aspects of Multimodal Systems, Department of Computer Science, University of Hamburg, Germany. He is one of the Chair Professors “Human-Computer Interaction” of the Department of Computer Science of Tsinghua University. He received his Bachelor (1986) and Master degree (1989) from the Department of Computer Science of Tsinghua University, and his PhD (1994) from the Department of Computer Science, University of Karlsruhe, Germany. His research interests include multimodal information processing, robot learning, service robots, smart vision systems and Embodied Intelligence. In these areas he has published over 120 journal and conference papers, six book chapters and two research monographs. He leads numerous basic research and application projects, including the EU basic research programs and the Collaborative Research Centre supported by the German Research Council. Dr. Zhang has received multiple awards including the IEEE ROMAN Best Paper 2002. 相似文献
Jianwei ZhangEmail: |
Calin Rotaru is a PhD candidate at the Department of Computer Science, University of Hamburg, Germany. His PhD work focuses on the topic color machine vision for driver assistance systems and is supported by Volkswagen AG, Group Research Electronics. He graduated (2002) with the topic “Stereo Camera Based Object Recognition” for Driver Assistance Systems from the Faculty of Automation and Computer Science of the Technical University of Cluj-Napoca, Romania. His research interests include color machine vision, smart vision systems, multisensorial data fusion and vision in driver assistance systems. Thorsten Graf received the diploma (M.Sc.) degree in computer science and the Ph.D. degree (his thesis was on “Flexible Object Recognition Based on Invariant Theory and Agent Technology”) from the University of Bielefeld, Bielefeld, Germany, in 1997 and 2000, respectively. In 1997 he became a Member of the “Task Oriented Communication” graduate program, University of Bielefeld, funded by the German research foundation DFG. In June 2001 he joined Volkswagen Group Research, Wolfsburg, Germany. Since then, he has worked on different projects in the area of driver assistance systems as a Researcher and Project Leader. He is the author or coauthor of more than 40 publications and owns several patents. His research interests include image processing and analysis dedicated to advanced comfort/safety automotive applications. Dr. Jianwei Zhang is full professor and director of the Institute of Technical Aspects of Multimodal Systems, Department of Computer Science, University of Hamburg, Germany. He is one of the Chair Professors “Human-Computer Interaction” of the Department of Computer Science of Tsinghua University. He received his Bachelor (1986) and Master degree (1989) from the Department of Computer Science of Tsinghua University, and his PhD (1994) from the Department of Computer Science, University of Karlsruhe, Germany. His research interests include multimodal information processing, robot learning, service robots, smart vision systems and Embodied Intelligence. In these areas he has published over 120 journal and conference papers, six book chapters and two research monographs. He leads numerous basic research and application projects, including the EU basic research programs and the Collaborative Research Centre supported by the German Research Council. Dr. Zhang has received multiple awards including the IEEE ROMAN Best Paper 2002. 相似文献
23.
This paper reports on an ergonomic study carried out during the design of a cutting machine-tool for the composite material in carbody parts casting. During this design process, the users’ needs were inferred by the designers on the basis of their own mental representations of the use of the new device. These representations of the users’ needs, correct or false, play a decisive role in the choice of a solution. The aim of the study is to identify their particularity. Analyzing the design meetings, we have highlighted that users are considered either as subsystems or basic design principles or elements of an imagined scenario. We have shown that these representations are linked to the types of meetings held during the design process. Accordingly, a diversification of the types of meetings should be promoted by the project leader, so that designers extend their points of view of the operators. 相似文献
24.
25.
Solute transport in natural streams is a complex phenomenon that involves both in-stream dispersion and mass exchange with the porous zones surrounding the water body. Due to the complex nature of the riverine systems several models may be used to simulate and analyze the transport of solutes with different degrees of complexity. The bedform-induced hyporheic transport is a stream-subsurface exchange mechanism that can be reproduced in controlled systems, such as laboratory flumes. Application of a simple Fickian diffusion model to laboratory data obtained with passive solutes and stationary bedforms proves successful within a range of durations of the contamination process. A dimensionless form of the diffusion coefficient, scaled with dynamic, physical, and geometric properties of the system is derived by comparison with another physically based model. A prediction of the dimensionless diffusion coefficient is obtained as a function of the timescale of the exchange process and is validated with a few sets of results from laboratory tests. 相似文献
26.
Daniela Graf Stillfried Martti Toivakka Parvez Alam 《Journal of Materials Science》2013,48(24):8449-8453
This brief communication describes the application and utility of thin film coral-mimetic coatings to natural fibres and provides quantitative values for the actual enhancement of their flexural properties. 相似文献
27.
Charlotte Szewczykowski Christian Mardin Marianna Lucio Gerd Wallukat Jakob Hoffmanns Thora Schrder Franziska Raith Lennart Rogge Felix Heltmann Michael Moritz Lorenz Beitlich Julia Schottenhamml Martin Herrmann Thomas Harrer Marion Ganslmayer Friedrich E. Kruse Martin Krter Jochen Guck Robert Lmmer Matthias Zenkel Andreas Gießl Bettina Hohberger 《International journal of molecular sciences》2022,23(13)
Long COVID (LC) describes the clinical phenotype of symptoms after infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Diagnostic and therapeutic options are limited, as the pathomechanism of LC is elusive. As the number of acute SARS-CoV-2 infections was and is large, LC will be a challenge for the healthcare system. Previous studies revealed an impaired blood flow, the formation of microclots, and autoimmune mechanisms as potential factors in this complex interplay. Since functionally active autoantibodies against G-protein-coupled receptors (GPCR-AAbs) were observed in patients after SARS-CoV-2 infection, this study aimed to correlate the appearance of GPCR-AAbs with capillary microcirculation. The seropositivity of GPCR-AAbs was measured by an established cardiomyocyte bioassay in 42 patients with LC and 6 controls. Retinal microcirculation was measured by OCT–angiography and quantified as macula and peripapillary vessel density (VD) by the Erlangen-Angio Tool. A statistical analysis yielded impaired VD in patients with LC compared to the controls, which was accentuated in female persons. A significant decrease in macula and peripapillary VD for AAbs targeting adrenergic β2-receptor, MAS-receptor angiotensin-II-type-1 receptor, and adrenergic α1-receptor were observed. The present study might suggest that a seropositivity of GPCR-AAbs can be linked to an impaired retinal capillary microcirculation, potentially mirroring the systemic microcirculation with consecutive clinical symptoms. 相似文献
28.
Eline A. M. Ruigrok Nicole S. Verkaik Erik de Blois Corrina de Ridder Debra Stuurman Stefan J. Roobol Dik C. Van Gent Marion de Jong Wytske M. Van Weerden Julie Nonnekens 《International journal of molecular sciences》2022,23(14)
Prostate specific membrane antigen targeted radionuclide therapy (PSMA-TRT) is a promising novel treatment for prostate cancer (PCa) patients. However, PSMA-TRT cannot be used for curative intent yet, thus additional research on how to improve the therapeutic efficacy is warranted. A potential way of achieving this, is combining TRT with poly ADP-ribosylation inhibitors (PARPi), which has shown promising results for TRT of neuroendocrine tumor cells. Currently, several clinical trials have been initiated for this combination for PCa, however so far, no evidence of synergism is available for PCa. Therefore, we evaluated the combination of PSMA-TRT with three classes of PARPi in preclinical PCa models. In vitro viability and survival assays were performed using PSMA-expressing PCa cell lines PC3-PIP and LNCaP to assess the effect of increasing concentrations of PARPi veliparib, olaparib or talazoparib in combination with PSMA-TRT compared to single PARPi treatment. Next, DNA damage analyses were performed by quantifying the number of DNA breaks by immunofluorescent stainings. Lastly, the potential of the combination treatments was studied in vivo in mice bearing PC3-PIP xenografts. Our results show that combining PSMA-TRT with PARPi did not synergistically affect the in vitro clonogenic survival or cell viability. DNA-damage analysis revealed only a significant increase in DNA breaks when combining PSMA-TRT with veliparib and not in the other combination treatments. Moreover, PSMA-TRT with PARPi treatment did not improve tumor control compared to PSMA-TRT monotherapy. Overall, the data presented do not support the assumption that combining PSMA-TRT with PARPi leads to a synergistic antitumor effect in PCa. These results underline that extensive preclinical research using various PCa models is imperative to validate the applicability of the combination strategy for PCa, as it is for other cancer types. 相似文献
29.
Kollmann Immel Holdheide M. Antonoff H. Mayer-Wegelin Frey-Wyssling Eidmann Thiele J. S. Cammerer A. v. Wacek Klauditz Scheer A. Nowak Gumz Vorreiter Finkbeiner Müller Munds E. Becker A. Kraus Fessel Keylwerth A. Troche Graf B. Thunell Tiemann Bäseler 《Holz als Roh- und Werkstoff》1942,5(10):363-371
Ohne Zusammenfassung 相似文献
30.
Ohne Zusammenfassung 相似文献