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11.
T. D. James M. G. Scullion P. C. Ashok A. Di Falco K. Dholakia T. F. Krauss 《Microfluidics and nanofluidics》2011,11(5):529-536
We demonstrate a microfluidics-based fluorescence detection device where the filters, source, detector, and electronically controlled valves are embedded into a Polydimethylsiloxane (PDMS)-based microfluidic chip. The device reported here has been specifically designed for chlorophyll a fluorescence sensing in autonomous systems, such as oceanic applications. In contrast to a monolithic approach, the modular approach made the fabrication of this device simpler and cheaper. For fluorescence detection, an InGaN/GaN LED is used as the excitation source to specifically excite chlorophyll a; a metal-dielectric Fabry?CPerot filter was used to extinguish out-of-band excitation. A simple Si photodiode is used as detector and provided with a thermally evaporated CdS emission filter to block the excitation source. This filter combination provides an excellent solution to the difficult problem of combining high-rejection excitation and emission filters in an integrated thin-film format. Furthermore, the metal-dielectric filter provides a much broader angular response than a comparable multilayer Bragg mirror, which is a key advantage in the integrated format. We use a novel paraffin wax-based valve design affords low power single-use actuation, between 0.5 and 1 J per actuation and withstands 0.6 bar differential pressure, which provides better performance than its previously reported counterparts. The remote valve-controlled operation of the fluorescence detection system is demonstrated, illustrating the measurement of a chlorophyll a solution, with a detection limit of 340 ??M and subsequent valve-controlled flushing of the measurement reservoir. 相似文献
12.
This paper focuses on a restrained concretization of the general NP-hard Container Loading Problem that arises from a real world application. This particular problem can be informally described as: given different sets of bins and boxes, find the packing of the boxes into the smallest number of bins obeying some additional restrictions on the placement. The mathematical programming formulation that appears to better model this application is the Three-dimensional Bin-Packing Problem (3D-BPP) which is no more than an extension of the classic Bin-Packing Problem to the orthogonal packing of solid objects.We present an alternative non-linear formulation for the 3D-BPP version as well as new designed heuristic algorithms (CPBOX and BOXCP) for the approximation of the optimal solution using boxes and bins of heterogeneous dimensions. Moreover, we also present a heuristic specifically designed to work under very particular storage application restrictions. The numerical results indicate that all of these new heuristics have good performance standards especially when applied to replications of real input data. 相似文献
13.
This study examined the mediating role of service climate in the prediction of employee performance and customer loyalty. Contact employees (N=342) from 114 service units (58 hotel front desks and 56 restaurants) provided information about organizational resources, engagement, and service climate. Furthermore, customers (N=1,140) from these units provided information on employee performance and customer loyalty. Structural equation modeling analyses were consistent with a full mediation model in which organizational resources and work engagement predict service climate, which in turn predicts employee performance and then customer loyalty. Further analyses revealed a potential reciprocal effect between service climate and customer loyalty. Implications of the study are discussed, together with limitations and suggestions for future research. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
14.
In this study, we analyse the effect that external sources of knowledge and absorptive capacity exert on a firm's output innovation. In addition, we examine the moderating influence of absorptive capacity on the effect that technological opportunities have on output innovation. Empirical research was carried out on a sample of 91 Spanish firms from the ceramic tile industry. Absorptive capacity is operationalized by ‘systematic or continuous R&D’ and output innovation by ‘percentage of sales from new products’. Technological opportunities are divided into several industry and non‐industry related variables. Our results show the positive effect that both the industry's technological opportunities and a systematic approach to R&D exert on output innovation. Moreover, firms with a systematic approach to R&D usually achieve higher innovation output than firms which do not follow this approach. The innovation results of this second group decrease as a result of embedded technology acquisition. 相似文献
15.
Shengshi Huang Marisa Ninivaggi Walid Chayoua Bas de Laat 《International journal of molecular sciences》2021,22(8)
The antiphospholipid syndrome (APS) is characterized by thrombosis and/or pregnancy morbidity with the persistent presence of antiphospholipid antibodies (aPLs). Laboratory criteria for the classification of APS include the detection of lupus anticoagulant (LAC), anti-cardiolipin (aCL) antibodies and anti-β2glycoprotein I (aβ2GPI) antibodies. Clinical criteria for the classification of thrombotic APS include venous and arterial thrombosis, along with microvascular thrombosis. Several aPLs, including LAC, aβ2GPI and anti-phosphatidylserine/prothrombin antibodies (aPS/PT) have been associated with arterial thrombosis. The Von Willebrand Factor (VWF) plays an important role in arterial thrombosis by mediating platelet adhesion and aggregation. Studies have shown that aPLs antibodies present in APS patients are able to increase the risk of arterial thrombosis by upregulating the plasma levels of active VWF and by promoting platelet activation. Inflammatory reactions induced by APS may also provide a suitable condition for arterial thrombosis, mostly ischemic stroke and myocardial infarction. The presence of other cardiovascular risk factors can enhance the effect of aPLs and increase the risk for thrombosis even more. These factors should therefore be taken into account when investigating APS-related arterial thrombosis. Nevertheless, the exact mechanism by which aPLs can cause thrombosis remains to be elucidated. 相似文献
16.
Lars Arnberg Marisa Di Sabatino Eivind ?vrelid 《Transactions of the Indian Institute of Metals》2012,65(6):509-513
Silicon is the dominating material in solar cells. Monocrystalline and multicrystalline cells have approximately equal market shares and are produced from wafers, cut from single crystals produced by Czochralski (CZ) pulling or from polycrystalline ingots made by directional solidification, respectively. The present paper reviews how demands for lower cost, better yield, higher efficiency and use of less pure silicon in solar cells are addressed by advanced solidification processing. In monocrystalline solar silicon, careful growth control results in less point defects, and better efficiency. Continuous- or semi-continuous CZ growth processes are being developed for better productivity and lower cost. In multicrystalline solar silicon, extended defects such as dislocations and grain boundaries decrease efficiency, particularly in combination with new, less expensive, but more contaminated silicon feedstock. This problem is addressed by control of nucleation and growth of ingots with larger grains, preferred grain orientation and lower dislocation density. 相似文献
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This paper concerns the patterns of food crop choice in a multicropping setting, in which production risk considerations and rainfall uncertainty are likely to be critical factors. The analysis employed plot level panel data from Ethiopia, combined with 30?year meteorological data corresponding to the survey villages used to construct seasonal and yearly rainfall variability. Using the single index approach, the riskiness of crop portfolio was constructed at a household level, taking into account the multicropping nature of the farming system. The combined riskiness of crops grown at a household level responded negatively to annual rainfall variability, with seasonal rainfall variability having a less consistent impact. Farmers are, therefore, more likely to select less risky crop portfolios even when intercrop interactions are taken into account. 相似文献
20.
Gianluigi De Falco Mario Commodo Carmela Bonavolontà Giovanni Piero Pepe Patrizia Minutolo Andrea D’Anna 《Combustion and Flame》2014
Optical and electrical properties of carbonaceous particles produced in laboratory scale, premixed ethylene/air flames are obtained. Light absorption and Raman spectroscopy show that the change in particle nanostructure follows a graphitization trajectory as the flame richness increases. The optical band gap decreases and the size of the aromatic network in the particle increases, while the interlayer spacing between parallel layers decreases. The electrical conductivity of the materials increases by increasing flame richness in agreement to the graphitization trajectory. A non-ohmic behavior has been found and explained in terms of electron tunneling in a percolative network. Our results show that the electrical properties of flame formed carbon nanoparticles are strongly dependent on their nanostructure, and hence they have to be used carefully for the determination of particle concentration with conductometric sensors. Moreover, the dependence of the electrical properties of combustion formed particles might be useful for the development of cheap sensors for the selective detection of different classes of combustion aerosols. 相似文献