Synergized poly(lactic acid)–hydroxyapatite composites: Biocompatibility study

In vitro biocompatibility of impact modified composites produced from poly(lactic acid) (PLA) and hydroxyapatite (HA) is reported in this study. Surface modification was previously used to facilitate the dispersion of HA in PLA, whereas impact property of the PLA-HA composites was deliberately enhanced as it was necessary. Herein, osteoblast cell culture assay was used to assess the possible effects of HA surface modification and impact modification on the cell behavior in physiological media. Furthermore, antimicrobial properties of the HA were assessed. Evidence of HA modification was confirmed through elemental and spectroscopic analysis. Incorporation of HA offered better cell attachment and proliferation to the PLA matrix, with significant increase in the cell viability (%). Also, modification of HA did not present obvious cytotoxicity to the PLA-HA composite. Conversely, incorporation of impact modifier slowed down the rate of cell proliferation on the composite surface but facilitates increased wettability. © 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019 , 136, 47400.     

Adaptive memetic method of multi-objective genetic evolutionary algorithm for backpropagation neural network

Neural Computing and Applications - In recent years, multi-objective evolutionary optimization algorithms have shown success in different areas of research. Due to their efficiency and power, many...     

Effects of TiO2 on microstructural,mechanical properties and in-vitro bioactivity of plasma sprayed yttria stabilised zirconia coatings for dental application

One of the most compatible coatings, known as yttria-stabilised zirconia polycrystal (YZP) is deposited on metallic Ti alloys due to its excellent hardness and aesthetic value as well as its low affinity for plaques. However, poor bioactivities of YZP and the existence of micro crack propagations due to the aging of YZP may result in spontaneous implant failure thus limiting its clinical use. In this work, YZP coating reinforced titania (TiO₂), which is formed via a plasma spray technique was investigated in order to enhance the bioactivity and the mechanical properties of YZP coatings for dental implants. Based on microstructural studies performed on the deposited coating, a distinguished lamellar structure comprising YZP and TiO₂ was observed. It was found that the reinforcement of TiO₂ in YZP coating significantly reduced the crack due to the improved densities and the lamellar structure. The mechanical properties were also found to improve with 90% of hardness, 45% of adhesion strength and 54% of Young's Modulus with TiO₂ addition, which is desirable for dental implants. An in-vitro bioactivity test was then conducted by immersing the coatings in a simulated body fluid (SBF). As a result, an apatite formation was found on the YZP/TiO₂ coating surface after 3 days of immersion. Besides, it was verified in an XRD analysis that the crystalline TiO₂ was found in a rutile phase which was highly effective in generating apatite (natural mineral in human bones) on YZP coatings, proving that the bioactivities of the coating were significantly improved. Further studies were also performed on the SBF treatment, which took up to 14 days also demonstrated that only a small decrease in hardness was noted, indicating that YZP/TiO₂ coatings had reached an excellent mechanical stability.     

Synthesis and characterization of CaFe2O4 nanoparticles via co-precipitation and auto-combustion methods

In this paper, the techniques for the synthesis of CaFe₂O₄ nanoparticles using the auto-combustion and co-precipitation methods are discussed. The effects of both methods on the microstructure and magnetic properties of the CaFe₂O₄ nanoparticles were compared. The CaFe₂O₄ powder was obtained after drying the synthesized sample via co-precipitation overnight in an oven at 80 °C. For auto-combustion method, the sol that was initially formed was gradually converted into a gel, which was then combusted at 250 °C. Finally, the CaFe₂O₄ nanoparticles were calcined at 550 °C. The different synthesis methods produced nanoparticles with different physical and magnetic properties in order to find an optimum size to be utilized for drug delivery applications. The results of the X-ray diffraction showed that both processes produced nanocrystals with an orthorhombic crystalline structure. It was noted from the measurements made with a transmission electron microscope (TEM) that the synthesis using the co-precipitation method produced nanoparticles with a size of about 10–20 nm, which was comparable with the size that was obtained when the auto-combustion method was used. The magnetic properties were investigated using a vibrating sample magnetometer (VSM), where the magnetic saturation (M_s) of CaFe₂O₄ for the sample synthesized using the co-precipitation method was 47.279 emu/g, which was higher than the magnetic saturation (M_s) of 31.10 emu/g obtained when the auto-combustion method was used. The hysteresis loops (Hc) for the samples were 17.380 G and 6.1672 G, respectively. Additionally, the elaborate properties mentioned above, such as the size and superparamagnetic properties of the synthesized CaFe₂O₄ nanoparticle size, were the characteristics required for drug delivery because the targeted therapy required nanoparticles with good magnetic properties, a suitable size, and which were non-toxic in order to have a potential application in targeted drug delivery systems.     

Effect of Treatments on the Physical and Morphological Properties of SPF/Phenolic Composites

This study aims at evaluating the physical properties and effects of fiber treatments of natural fiber reinforced polymer composite’s friction applications. Sugar palm fibers (SPFs) were used as fillers (≤ 150 µm) with phenolic resin to fabricate the composites by the hot press technique. The loading of SPFs varied from 0 to 40 vol.% with an interval of 10 vol.% in phenolic composites. The fibers were treated with sea water for 30 days, and with 0.5 M of alkaline solution for 4 hrs. Rockwell hardness, density, voids content, water/oil absorption, and moisture content were studied. Scanning electron microscopy (SEM) was used to investigate the morphology and interfacial bonding of the fiber-matrix in composites. With an increase in the SPF loading in the composites, the results indicated a decline in Rockwell hardness, an increase in water/oil absorption, and density. It was also observed that higher the density of the composites, lower was the voids content. In terms of physical properties, sea water treatment showed better improvement than alkaline treatment. The outcome of this research indicated that SPFs can be effectively used in reinforcing polymer composites, such as friction composites.     

Enhancement of Thermoelectric Behavior of La0.5Co4Sb12−x Te x Skutterudite Materials

Metallurgical and Materials Transactions A - In this work, the effects of Te doping on the microstructure and thermoelectric properties of the partially filled skutterudite La0.5Co4Sb12 compounds...     

A Risk Poker Based Testing Model for Scrum

In agile software development, project estimation often depends on group discussion and expert opinions. Literature claims that group discussion in risk analysis helps to identify some of the crucial issues that might affect development, testing, and implementation. However, risk prioritization often relies on individual expert judgment. Therefore, Risk Poker, a lightweight risk-based testing methodology in which risk analysis is performed through group discussion that outperforms the individual analyst’s estimation is introduced in agile methods. Keeping in view aforementioned benefits Risk Poker can offer, unfortunately, no study has been conducted to empirically prove its ability to improve the testing process to date. Therefore, this research is aimed at closing this research gap by (i) deploying Risk Poker technique as a risk-based strategy in the agile development lifecycle, and (ii) empirically evaluating improvement of the proposed test process. For this purpose, Risk Poker technique is coupled with test coverage for an innovated testing process in an agile project following Scrum in order to provide adequate test coverage for testing activity. A case study was conducted with 6 teams of undergraduate students to estimate test coverage using Risk Poker for an e-commerce system. Three teams estimated their user stories using Risk Poker, while the rest estimated individually and used an average to obtain the statistical combination. The results showed that the proposed usage of Risk Poker for risk analysis and estimate test coverage outperformed the averaged statistical estimation of risk analysis for user stories.     

Production of bacterial endoglucanase from pretreated oil palm empty fruit bunch by bacillus pumilus EB3

In this study, endoglucanase was produced from oil palm empty fruit bunch (OPEFB) by a locally isolated aerobic bacterium, Bacillus pumilus EB3. The effects of the fermentation parameters such as initial pH, temperature, and nitrogen source on the endoglucanase production were studied using carboxymethyl cellulose (CMC) as the carbon source. Endoglucanase from B. pumilus EB3 was maximally secreted at 37 degrees C, initial pH 7.0 with 10 g/l of CMC as carbon source, and 2 g/l of yeast extract as organic nitrogen source. The activity recorded during the fermentation was 0.076 U/ml. The productivity of the enzyme increased twofold when 2 g/l of yeast extract was used as the organic nitrogen supplement as compared to the non-supplemented medium. An interesting finding from this study is that pretreated OPEFB medium showed comparable results to CMC medium in terms of enzyme production with an activity of 0.063 U/ml. As OPEFB is an abundant solid waste at palm oil mills, it has the potential of acting as a substrate in cellulase production.     

Poly(lactic acid) composite films reinforced with microcrystalline cellulose and keratin from chicken feather fiber in 1-butyl-3-methylimidazolium chloride

Amphiphilic keratin from chicken feather fiber (CFF) and hydrophilic cellulose were incorporated as fillers into hydrophobic poly(lactic acid) (PLA) polymer blend. This study implemented ionic liquid (IL) of 1-butyl-3-methylimidazolium chloride (BMIMCl) to dissolve the 1 wt % fillers. The composite films were compared with and without the addition of IL prepared from five sets of ratios of CFF to MCC using measuring mixers and compression molding. Thermal analysis showed that increase in CFF composition decreases the glass-transition temperature (T _g), and crystallization temperature (T _c) as well as increases the degree of crystallinity. PLA composite with the 70/30 ratio of CFF to MCC was found to be the optimum composition in obtaining considerably low T _g and high crystallinity. BMIMCl enhanced the miscibility of the composites as observed in scanning electron microscope images and single T _g. Apart from creating porous structure and lowering mechanical hardness, BMIMCl also decreased the thermal stability of the PLA composites. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019 , 136, 47642.