Early development in males with Fragile X syndrome: a review of the literature

This article reviews the current bibliographic knowledge on early neurobehavioral development and milestones in Fragile X syndrome (FraX), with emphasis on males affected by the condition. Three broad areas of early development were examined: (1) gross and fine motor, (2) speech and language, and (3) social. The result of the current review indicates very limited information on the developmental milestones in all three areas. The scarce literature on motor development shows that in FraX there is an early developmental delay. Research on speech and language demonstrates pervasive deficits in conversational skills and severe developmental delay, with increasing discrepancy between language level and chronological age in young males with FraX. Finally, deficits in social development in FraX include abnormal gaze, approach and avoidance conflict, and high incidence of autistic spectrum disorders.     

Entwicklung rechtssicherer Web-Anwendungen

A broad variety of juridical requirements has to be considered during the development of Web-applications. Disregard of these requirements holds severe financial dangers. A complete compilation of juridical requirements is complicated due to the multitude of juridical areas and the variety of Web-applications. Therefore, a development-driven juridical framework is suggested. From a software engineering point of view it is crucial to capture requirements at an early stage of development in order to avoid much higher costs at a later time. Thus, specialized conceptual modelling methods are examined with regard to their capability to model juridical requirements. A lack of methodical support is identified which is addressed by a systematic adaption and extension of the eW3DT method.     

Changing toddlers' and preschoolers' attachment classifications: The circle of security intervention.

The Circle of Security intervention uses a group treatment modality to provide parent education and psychotherapy that is based on attachment theory. The purpose of this study was to track changes in children's attachment classifications pre- and immediately postintervention. Participants were 65 toddler- or preschooler- caregiver dyads recruited from Head Start and Early Head Start programs. As predicted, there were significant within-subject changes from disorganized to organized attachment classifications, with a majority changing to the secure classification. In addition, only 1 of the 13 preintervention securely attached children shifted to an insecure classification. Results suggest that the Circle of Security protocol is a promising intervention for the reduction of disorganized and insecure attachment in high-risk toddlers and preschoolers. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Search for Superconductivity in Lithium

We report on the results of a search for superconductivity in Li. We find no evidence for the predicted transition to superconductivity at any temperature down to 5 mK in magnetic fields down to 0.4 T. However, an unexpected Curie–Weiss temperature dependence in the magnetic susceptibility is observed. We discuss the possibility that this signal arises from the Li itself, the possibility that it arises from Kondo behavior, and the implications of the effect for the predicted T_c of Li.     

A decision model for operating two alternate energy generating systems

A solar energy generating system is to be supplemented by two conventional generating systems. A method for investigating the effect of various operating policies of the combined system on the productivity and availability is developed. Using a Markov-Chain approach for computing the long-run expectations of the objectives it was demonstrated that the use of a stand-by mode for one of the conventional systems was optimal. Numerical examples are presented to demonstrate the methodology both for special and more general cases.     

Pro- und Antioxydantien auf dem Fettgebiet XXVI: Anthochlore von Dahlia variabilis und Cosmos sulphureus

Pro- and Antioxidants in the Field of Fats XXVI: Anthochlores of Dahlia variabilis and Cosmos sulphureus The authors have determined the antioxidative activity of the anthochlor pigments of Dahlia variabilis and Cosmos sulphureus on methyl linoleate. It was found that the aglycones butein and sulphuretin exhibit stronger antioxidative action than the chalkone aglycone 2″,4,4″-trihydroxy chalcone. During the treatment of the two flowers, a splitting of the glycosides was observed. In the freshly cut Cosmos sulphureus variety no aglycones could be detected. Furthermore, the distribution of anthochlores in the various series of petals in Dahlia variabilis and Helichrysum bracteatum was studied.     

Optimal seat allocation for flights with one intermediate stop

During the time prior to departure of a flight with an intermediate stop decisions must be made concerning the allocation of reserved seats to passengers requesting space on the full or partial spans of the flight. The paper presents a model for finding the maximum allowable allocation of seats on the various spans at each time prior to departure such that a maximum expected contribution to profit for the flight is obtained.The model utilizes the time distribution of reservations and cancellations for both spans. Consideration is given to the effects of waitlists, standbys and overbookings. A Bayesian reassessment of probabilities is incorporated in a sequential decision procedure. A computer program was written to perform the calculations, and the results of a short sample problem which was run to test the validity of the model are presented.     

Hardened portland cement pastes of low porosity VI. Mechanism of the hydration process

The hydration of low-porosity portland cement pastes may be divided into three stages. The first stage starts with a fast hydration until 10 to 15% of the cement is hydrated (pre-dormant period), which is followed by a very slow hydration, caused by the formation of a coating on the cement grains (dormant period). After 15 to 20% of the cement is hydrated, the coating is ruptured, and a fast reaction starts, which lasts until about 30% of the cement is hydrated. This is the second stage of the reaction. In the third stage, the hydration slows down, due to retardation by the accumulating hydration products. The mechanism of the third stage is treated quantitatively. The diffusion through the very narrow pores between the hydration products is activated diffusion, and the apparent energy of activation of the diffusion is calculated.