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11.
12.
Ho-Kyung Kim Masanobu Shinozuka Sung-Pil Chang 《Canadian Metallurgical Quarterly》2004,130(7):848-857
A geometrically nonlinear buffeting analysis of a cable-stayed bridge in the time domain is described. The bridge structure is modeled with three-dimensional thin-walled beam elements and three-dimensional elastic catenary cable elements. Spatially correlated wind velocity fluctuations are modeled and simulated using an algorithm for generating sample functions of a stationary, multivariate stochastic process according to its prescribed cross-spectral density matrix. Aerodynamic damping and aerodynamic stiffness are formulated based on experimentally determined flutter derivatives. The focus of this paper is on the effect of fluctuating components of the spatially correlated wind velocity on the geometrically nonlinear buffeting response for an 870 m cable-stayed bridge. 相似文献
13.
This study utilizes remotely sensed pre- and post-disaster images in order to detect any change specifically associated with structural and major regional damage caused by natural disasters such as a strong earthquake. Currently, postdisaster reconnaissance is conducted using mostly ground-truth teams. Although by using this method high-resolution assessment can be provided, it is very time consuming, costly and sometimes not practical. This study investigates an unsupervised near near-time method of reconnaissance using a pair of coregistered remotely sensed images of the same scene acquired at different times as input. The output is an image (mostly binary) in which “changed” pixels are separated from “not-changed” ones. The approach is fully deterministic using principal component analysis, normalization and further setting a threshold to classify pixels. For verification, a set of multispectral images from Golcuk-Turkey 1999 earthquake was used. It is concluded the program generates very similar results as obtained by ground-truth teams. 相似文献
14.
15.
Katsumasa Tsurushima Masanobu Tsubaki Tomoya Takeda Takuya Matsuda Akihiro Kimura Honoka Takefuji Akane Okada Chiaki Sakamoto Toshihiko Ishizaka Shozo Nishida 《International journal of molecular sciences》2022,23(15)
Triple-negative breast cancer (TNBC) has the poorest prognosis of all breast cancer subtypes. Recently, the activation of NF-κB, which is involved in the growth and survival of malignant tumors, has been demonstrated in TNBC, suggesting that NF-κB may serve as a new therapeutic target. In the present study, we examined whether dimethyl fumarate (DMF), an NF-κB inhibitor, induces apoptosis in TNBC cells and enhances the apoptosis-inducing effect of paclitaxel and adriamycin. Cell survival was analyzed by the trypan blue assay and apoptosis assay. Protein detection was examined by immunoblotting. The activation of NF-κB p65 was correlated with poor prognosis in patients with TNBC. DMF induced apoptosis in MDA-MB-231 and BT-549 cells at concentrations that were non-cytotoxic to the normal mammary cell line MCF-10A. Furthermore, DMF inhibited NF-κB nuclear translocation and Survivin, XIAP, Bcl-xL, and Bcl-2 expression in MDA-MB-231 and BT-549 cells. Moreover, DMF enhanced the apoptosis-inducing effect of paclitaxel and adriamycin in MDA-MB-231 cells. These findings suggest that DMF may be an effective therapeutic agent for the treatment of TNBC, in which NF-κB is constitutively active. DMF may also be useful as an adjuvant therapy to conventional anticancer drugs. 相似文献
16.
Suzuki Atsushi Taguchi Masaya Oku Takeo Okita Masanobu Minami Satoshi Fukunishi Sakiko Tachikawa Tomoharu 《Journal of Materials Science: Materials in Electronics》2021,32(22):26449-26464
Journal of Materials Science: Materials in Electronics - Fabrication and characterization of methylammonium lead iodide perovskite solar cells incorporated with methylammonium bromide (MABr),... 相似文献
17.
Resolution of Epoxydienes by Reversed-Phase Chiral HPLC and its Application to Stereochemistry Assignment of Mulberry Looper Sex Pheromone 总被引:1,自引:0,他引:1
Guan-Qin Pu Masanobu Yamamoto Yaeko Takeuchi Hiroyuki Yamazawa Tetsu Ando 《Journal of chemical ecology》1999,25(5):1151-1162
Resolution of insect pheromonal cis-epoxydiene racemates derived from (Z,Z,Z)-3,6,9-trienes was examined with a reversed-phase chiral HPLC column. The results showed that a Chiralcel OJ-R column was suitable for separating the enantiomers having a C17–C23 unsaturated straight chain except for 9,10-epoxydienes with a C21–C23 chain. To determine the absolute configuration of the separated enantiomers, each of the optically active epoxydienes was hydrogenated over Pd-BaSO4 and its behavior was examined on this chiral column by cochromatography with the corresponding chiral epoxy compound having a saturated chain, which was prepared via a Sharpless epoxidation reaction. This analysis showed that the dextrorotatory C17–C23 3,4- and 6,7-epoxydienes and C17–C20 9,10-epoxydienes with shorter R
ts possess (3S,4R)-, (6S,7R)-, and (9R,10S) configurations, respectively, and the levorotatory enantiomers with longer R
ts possess the opposite configuration. An abdominal tip extract of the mulberry looper, Hemerophila artilineata Butler (Lepidoptera: Geometridae: Ennominae), included (9S,10R)-(Z,Z)-cis-9,10-epoxy-3,6-octadecadiene as a main sex pheromone component. The synthetic (9S,10R)-9,10-epoxydiene, rather than its antipode, elicited strong antennal and behavioral responses from the male moths in electrophysiological and field tests. 相似文献
18.
The ironmaking blast furnace is regarded as one of the biggest and most complex industrial reactors, because it includes various materials like gas, lump granular materials, liquids and powders and more than 30 major reactions and phase changes in a single reaction vessel. The mathematical simulator of this process developed in this study used the multi-fluid treatment as its framework, since the motions of these materials were governed by different flow mechanisms. The rates of the interactions among the phases and the chemical reactions were evaluated based on kinetic theories. The model successfully reproduced the fields of velocity, temperature and reaction in the furnace and its validity was confirmed. The simulator was also applied to a novel operation, namely the top gas recycling combined with the carbon-composite iron-ore charging and the waste plastics injection, and the advantages in furnace efficiency and environmental load were quantitatively indicated. 相似文献
19.
Moriwaki H Takagi Y Tanaka M Tsuruho K Okitsu K Maeda Y 《Environmental science & technology》2005,39(9):3388-3392
Perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) are shown to be globally distributed, environmentally persistent, and bioaccumulative. Although the toxicities of these compounds were reported, the cleanup procedure from the environment is not developed because of their inertness. In this report the sonochemical degradations of PFOS and PFOA to the products through the fission of the perfluorocarbon chains were observed and the half-life times of the PFOS and PFOA degradations under an argon atmosphere determined to be 43 and 22 min, respectively. The shortening of perfluorocarbon chain of PFOS and PFOA leads to the lowering of the toxicity in view of the decrease of the persistence, and the technique would contribute to the remediation of the environmental pollution by these compounds. 相似文献
20.
Yoshinobu Fujishiro Motoyuki Miyata Masanobu Awano Kunihiro Maeda 《Journal of the American Ceramic Society》2003,86(12):2063-2066
The thermal conductivity of polycrystalline Al-doped ZnO was controlled through the fabrication of nanostructured polycrystalline materials, by hot-pressing nanosized Zn1– x Al x O ( x = 0.01, 0.02) particles, which were synthesized by a coprecipitation and spray-drying method. This process resulted in an improved thermoelectric power factor because of the nanosized Zn0.99 Al0.01 O particles of the polycrystalline products. The thermal conductivity also was decreased as a result of the formation of nanocrystalline Zn0.99 Al0.01 O. 相似文献