Reconstruction of bone fenestration on mandiblar by the guided bone regeneration methods with beta-TCP/PLGC membranes

Guided Bone Regeneration (GBR) is a method for bone tissue regeneration. In this method, membranes are used to cover bone defects and to block the invasion of the surrounding soft tissues. It would provide sufficient time for the osteogenic cells from bone marrow to proliferate and form new bony tissues. In spite of the potential usefulness of this method, no appropriate materials for the GBR membrane have been developed. Here we design the ideal mechanical properties of the GBR membranes and created novel materials, which is the composite of beta-tricalcium phosphate (beta-TCP) and block copolymer of L-lactide, glycolide, and epsilon-caplolactone (PLGC). In the animal experiments with the use of the GBR membranes for large bone defects, we observed significant enhancement in the bone regeneration after 12 weeks implantation and proved the effectiveness of the materials.     

13C NMR longitudinal relaxation time studies of a molecular tweezers derived from a calixarene-porphyrin conjugate

Zn(II)porphyrin-substituted calix[4]arene 1 serves as molecular tweezers for 1,4-diazabicyclo[2.2.2] octane (DABCO) selectively, which led to the formation of Ensemble I. The molecular segments composing the calixarene cavity change upon inclusion of DABCO as Ensemble I were evaluated through (13)C NMR longitudinal relaxation times (T(1)) for the first time. As for Ensemble I, the 1:1 complex should be formed. The T(1) values for Ensemble I are generally smaller than those for 1: in CDCl(2)CDCl(2), DT1 = 5.03 s for C-1, 5.31 s for C-2, 0.13 s for C-3, 0.7 s for C-4, and 0.16 s for C-5. This substantiates that the rings of Ensemble I are firmly freezed because of the two-point coordination by DABCO. In 1, the T1 values for C-3 are always greater than those for C-4, and the difference between C-3 and C-4 is slight. As for Ensemble I, on the other hand, the difference between C-3 and C-4 is large. We can suggest two different motions for phenol units in 1 and Ensemble I: a rotational motion around a C-1 to C-4 axis (A) and a seesaw motion around a C-2 to C-2' axis (B). The data indicate that in Ensemble I motion (A) is predominant over motion (B). This indicates that motion (B) is specifically suppressed because of the two-point coordination interactions in Ensemble I.     

Photocurrent generators derived from non-covalently assembled soft-matter molecular system

It is rather difficult to design a multilayer photocurrent generator system on the ITO electrode, however, the preparation of thin film with high surface concentration of donor units is indispensable in order to achieve high conversion efficiency. The polymer film of porphyrin bearing pyroles on the electrode was prepared by the potential sweep method. It was indicated that the self-aggregation can be suppressed by encapsulation of the porphyrin unit in the cavity of macro-cyclic host molecule, cyclodextrin. We established the non-equilibrium host-guest system with porphyrins and cyclodextrins for the first time. The photocurrent density and the quantum yield in the porphyrin-cyclodextrin system are remarkably improved. It was demonstrated that the high quantum yield, perhaps 25 times larger, arises from the isolation of the porphyrin unit by cyclodextrin through host-guest interactions.     

Structure and performance of cationic assembly dispersed in amphoteric surfactants solution as a shampoo for hair damaged by coloring

In recent years, hair coloring gains popularity as a trend of consumer's hair care. This coloring frequently damages hair. In response to this, a new shampoo-base was developed for repairing hair damaged by coloring. The new shampoo-base was prepared by dispersing cationic assembly in a solution of amphoteric surfactants. The mixture of behenyl trimethyl ammonium chloride (C22TAC) and behenyl alcohol (C22OH) was applied as the cationic assembly, which are dispersed in amido propyl betaine laurate (LPB) solution. LPB, which behaves as an amphoteric surfactant, was used as the wash-base. It was verified from the results on the measurements of DSC, calorimeter polarization, cryo-SEM and X-ray diffraction that the cationic assembly has a crystalline structure in the LPB solution. The new shampoo-base was highly efficient to change the color-damaged hair from hydrophilic to hydrophobic. The friction level of the hair washed with the new shampoo-base recovered to the same state as that of healthy hair. The exfoliation of cuticle was reduced after washing with the new shampoo-base.     

Tiny-scale “stealth” current sensor to probe power semiconductor device failure

“Stealth” electric current probing technique for power electronics circuits, power device modules and chips makes it possible to measure electric current without any change or disassembling the circuit and the chip connection for the measurement. The technique consists of a tiny-scale magnetic-field coil, a high speed analog amplifier and a digitizer with numerical data processing. This technique can be applied to a single bonding wire current measurement inside IGBT modules, chip scale current redistribution measurement and current measurement for surface mount devices. The “stealth” current measurement can be utilized in the failure mechanism understanding of power devices including IGBT short circuit destruction.     

CFD analyses in tight-lattice subchannels and seven-rod bundle geometries of a Super Fast Reactor

This paper presents CFD analyses in heat unsymmetric subchannels and heat symmetric seven-rod bundle geometries of a Super Fast Reactor (Super FR) fuel assembly using STAR-CD. The purpose of CFD analyses in heat unsymmetric subchannels is to evaluate the effect of the power differences on the heat transfer in subchannels of the Super Fast Reactor. For heat symmetric seven-rod bundles, the effects of the gap clearance between the fuel rod and the assembly wall and the displacement of the fuel rod on the circumferential temperature distributions and Maximum Cladding Surface Temperature (MCST) are analyzed. The results show that larger power difference between fuel rods gives larger circumferential temperature difference of the hottest fuel rods. Considering cross flow between edge and ordinary subchannels, 1 mm gap between the fuel rod and the assembly wall is better for small MCST although the circumferential temperature difference in edge subchannel is large. MCST increases exponentially with the displacement. The relative error of displacement should be less than 1% if the allowable increment of MCST due to displacement is less than 6 °C.     

Effect of enzymatic treatment on sedimentation and flocculation abilities of solid particles in rice washing drainage and its relationship with protein profiles

An efficient and rapid adventitious shoot regeneration system from young cotyledons of Jatropha curcas L. was developed. After testing several combinations of plant growth regulators, the highest regeneration frequency was obtained for the medium supplemented with 3 mg/l BA and 0.1 mg/l IBA. This system will be useful for promoting genetic improvement efforts in J. curcas.     

Critical heat flux of natural circulation boiling in a vertical tube: Effect of oscillation and circulation on CHF

An experimental study has been made to elucidate an effect of oscillated flow induced near critical heat flux (CHF) and natural circulated flow of vapor and liquid in a vertical tube on the CHF. The experiment has been carried out for the condition of heated tube length of L=100-1000 mm, tube diameter of D=4-9 mm and the CHF is measured under the condition that the exit of the unheated tube connecting the heated tube is extruded into a vapor chamber to prevent a liquid flowing into the heated tube from the top. The experiment reveals that the CHF for D=7 and 9 mm and any tube length from 100 to 1000 mm becomes identical to that for the case of the tube top in the liquid, while the CHF for D=4 and 5 mm is smaller than that for the case of the tube top in the liquid due to no liquid supply from the top. It is found that the oscillation induced near the CHF increases the CHF.     

Mechanism of increase of electrostatic charging tendency in insulating oil for oil‐immersed transformer

The mechanism of the increase in the electrostatic charging tendency (ECT) of insulating oil and causative compounds were investigated by accelerated deterioration tests with the addition of various compounds. Although the ECT of the insulating oil was almost constant when only sulfoxide compounds were added, a marked increase was observed when either hydrochloric acid or moisture, which was considered to be generated by the aging of insulating oil, was also added to oil containing sulfoxide compounds. It is assumed that the sulfonium ion, which is generated by the reaction between sulfoxide compounds and hydrogen ion, is the compound that directly contributes to the increase in the ECT. Hydrogen ions can be supplied from organic acids generated by the oxidation of hydrocarbons in aging insulating oil. It is considered that the increase in the ECT of insulating oil is caused by the generation of sulfoxides by the oxidation of sulfide, which are present in fresh oil (originating compounds), and the generation of sulfonium ions by a reaction between sulfoxide and hydrogen ions, which are formed during aging. © 2011 Wiley Periodicals, Inc. Electr Eng Jpn, 176(4): 26–33, 2011; Published online in Wiley Online Library ( wileyonlinelibrary.com ). DOI 10.1002/eej.21113     

The role of alpha-dystrobrevin in striated muscle

Muscular dystrophies are a group of diseases that primarily affect striated muscle and are characterized by the progressive loss of muscle strength and integrity. Major forms of muscular dystrophies are caused by the abnormalities of the dystrophin glycoprotein complex (DGC) that plays crucial roles as a structural unit and scaffolds for signaling molecules at the sarcolemma. α-Dystrobrevin is a component of the DGC and directly associates with dystrophin. α-Dystrobrevin also binds to intermediate filaments as well as syntrophin, a modular adaptor protein thought to be involved in signaling. Although no muscular dystrophy has been associated within mutations of the α-dystrobrevin gene, emerging findings suggest potential significance of α-dystrobrevin in striated muscle. This review addresses the functional role of α-dystrobrevin in muscle as well as its possible implication for muscular dystrophy.