Gated MaxWIP: A strategy for controlling multistage production systems

This study considers serial production systems with exponential processing times. The systems are balanced, i.e. all resources have the same production rate capacity. Preceding the system there is a 'gate' set to regulate the flow of material into the system. A control strategy directs each resource when to work or stay idle. The trade-off is between throughput (TP) and work-in-process (WIP). G-MaxWIP is a production control strategy allowing resources, except for the gate, to work unconstrained. The gate 'shuts' once the system's WIP reaches a maximum allowable level. We study the properties of G-MaxWIP and compare it to 'simple pull' and CONWIP. Our main findings are: G-MaxWIP is superior to simple pull. For any simple pull system operating a fixed set of resources it is possible to find G-MaxWIP systems that operate the same resources with less WIP while maintaining the same (or higher) TP. G-MaxWIP is superior to CONWIP. For any CONWIP system operating a fixed set of resources it is possible to find G-MaxWIP systems that operate the same resources with less WIP while maintaining the same (or higher) TP.     

Carvacrol and trans-Cinnamaldehyde Reduce Clostridium difficile Toxin Production and Cytotoxicity in Vitro

Clostridium difficile is a nosocomial pathogen that causes a serious toxin-mediated enteric disease in humans. Reducing C. difficile toxin production could significantly minimize its pathogenicity and improve disease outcomes in humans. This study investigated the efficacy of two, food-grade, plant-derived compounds, namely trans-cinnamaldehyde (TC) and carvacrol (CR) in reducing C. difficile toxin production and cytotoxicity in vitro. Three hypervirulent C. difficile isolates were grown with or without the sub-inhibitory concentrations of TC or CR, and the culture supernatant and the bacterial pellet were collected for total toxin quantitation, Vero cell cytotoxicity assay and RT-qPCR analysis of toxin-encoding genes. The effect of CR and TC on a codY mutant and wild type C. difficile was also investigated. Carvacrol and TC substantially reduced C. difficile toxin production and cytotoxicity on Vero cells. The plant compounds also significantly down-regulated toxin production genes. Carvacrol and TC did not inhibit toxin production in the codY mutant of C. difficile, suggesting a potential codY-mediated anti-toxigenic mechanism of the plant compounds. The antitoxigenic concentrations of CR and TC did not inhibit the growth of beneficial gut bacteria. Our results suggest that CR and TC could potentially be used to control C. difficile, and warrant future studies in vivo.     

Optimisation of maintenance strategy for rural road network using genetic algorithm

The objective of this paper is to develop an optimised maintenance strategy for the rural road network of Kerala state. This is accomplished with the development of a bi-objective deterministic optimisation model which simultaneously satisfies the objectives of both minimisation of total maintenance cost and maximisation of performance of the road network. The model is capable of planning the maintenance activities over a multi-year planning period. The performance of the road network is accounted using the composite index, namely Pavement Condition Index. The constraint-based genetic algorithm was used as the optimisation tool since it very well takes care of the combinatorial nature of the network-level pavement maintenance programming. The applicability of the model is illustrated using a case study for the rural road network of Kerala state in India. The effort made through this research work to develop a suitable Pavement Maintenance and Management System for rural road network can lead to the proper maintenance and upkeep of the rural roads, thereby triggering a positive impact on the Indian economy.     

Coercivity Control of Variable-Length Iron Chains in Phthalocyanine Thin Films

The magnetic characteristics of iron phthalocyanine thin films are studied with a vibrating sample magnetometer, identifying a ferromagnetic transition temperature at 4.5?K. The metal ions at the center of the molecule are self-assembled along chains producing quasi one-dimensional magnetic chains of variable length in the thin films. The average chain length is varied from 20 to 300?nm via substrate temperature during deposition. Below the critical transition temperature, the magnetization curves have the shape of wasp-waisted or constricted loops. The in-plane chain length modulates the coercivity and saturation field and larger grains increase the coercivity significantly. First-order reversal curves of the wasp-waisted hysteresis loops reveal a long narrow strip that suggests a broad distribution of coercive fields and weak intergrain magnetic interactions. These findings are also supported through simulations based on the Preisach model.     

Effect of diethyl ether blended with neem oil methyl esters in CI engine

Vegetable oils are now considered to be a potential alternative that can be used in place of partial or total substitution of diesel fuels. In this study, we used diethyl ether as an oxygenated additive to investigate the possible use of higher percentages of biodiesel in an unmodified diesel engine. Neem oil was selected for biodiesel production. The tests were performed at a steady-state condition in a single-cylinder constant speed DI diesel engine. The combustion process involved in diesel engine would be improved and the particulate matter would be reduced if these biodiesels are blended. An experimental investigation is carried out to establish the emission characteristics of a direct injection diesel engine using diethyl ether as additive in Neat Neem oil Biodiesel. Emissions of hydro carbon oxides of nitrogen and carbon monoxide significantly reduced by adding diethyl ether into neem oil biodiesel at 10% and 20% on volume basis.     

A characterization of partial blocks in weighted graphs

Some of the classical connectivity concepts in Graph theory are generalized in this article. Strong and strongest strong cycles are introduced. Partial blocks are characterized using strongest paths. Some necessary and sufficient conditions for a weighted graph to be a partial block are also presented.     

Fermented milk obtained with kefir grains as an ingredient in breadmaking

The objectives of this research were to study the effect of the addition of lyophilised kefir milk to premixes for household production of bread and evaluate the quality attributes of them. Four lyophilised samples were obtained from the followings: skim milk, acidified skim milk, fermented skim milk and neutralised fermented skim milk. Breads were prepared with commercial wheat flour, lyophilised milk samples and yeast through a straight dough process. Quality was assessed through loaf volume, crumb porosity and moisture, crumb texture and crust colour. Changes in texture and starch recrystallisation by X‐ray diffractometry were determined after 1 and 3 days of storage at room temperature. Breads with acidified milks showed the highest specific volumes and crumbs with the best texture properties. Crystallinity in bread with fermented milks was higher than for skim milk sample. This would indicate that there would be a certain effect of the type of milk processing on the promotion of starch retrogradation.     

Enriching our theoretical repertoire: the role of evolutionary psychology in technology acceptance

Information systems (IS) research has drawn heavily on social and cognitive psychology to explain technology adoption. Indeed, the many variations of the technology acceptance model all share these same theoretical foundations. Focusing exclusively on the socio-cognitive lens can lead to overlooking enhanced explanations of technology acceptance, such that new theoretical perspectives may be warranted. In this qualitative grounded theory study, we discovered how the lens of evolutionary psychology, as embodied in the Four-Drive model, was helpful in understanding technology acceptance across three organizational sites. We contend that evolutionary psychology is an important addition to the theoretical repertoire of IS researchers, and propose including ‘evolved psychological mechanisms’ within traditional models of technology acceptance.     

On the Properties of Fuzzy Switching Functions

Abstract

A strictly binary approach to the treatment of switching circuits today is not always adequate to describe systems in the real world. This approach is partly due, to the relative simplicity of designing binary switching systems, and to the fact that basic switching modules in common use are two-positional. Consequently, every variable in Boolean logic is assumed to be two-valued. However, because of real-world constraints, the attributes of system variables are often ambiguously defined. In other words, quite often variables might have values other than falsehood and truth. Cases with such attributes arise, for example in artifical intelligence and related subjects. Ever since Zadeh introduced the idea of fuzzy set theory [11 by utilizing the concept of membership grade, a number of authors have been concerned with the analysis and applications of fuzzy models. Especially, the relation of fuzzy to switching systems have been discussed in [2]–[12] and by other researchers in relation to other topics.

In this paper we are concerned with the study of fuzzy switching functions and their properties. Special attention is devoted to their minimization, enumeration, and their application to Boolean static hazard detection.