An optimisation strategy in a digital environment applied to neonatal chest imaging

The aim of this study was to find the optimum tube voltage for neonatal chest imaging in computed radiography. The study was designed to take full advantage of the benefits of digital imaging, for example, by comparing the tube voltages at constant effective dose. A phantom study using a living rabbit was first conducted. Images were collected at tube voltages ranging from 40 to 90 kV(p). The reproduction of four structures (central vessels, peripheral vessels, carina and thoracic vertebrae) was rated by 10 radiologists. The reproduction of both central and peripheral vessels was relatively independent of tube voltage. The carina was better reproduced at higher tube voltages whereas the opposite was true for the thoracic vertebrae. Based on the higher importance of the reproduction of the carina it was decided that 90 kV(p) was the optimal tube voltage. To validate the result from the phantom study, a follow-up study was conducted in which images of neonates collected at the tube voltage regularly used at Sahlgrenska University Hospital (70 kV(p)) were compared with images collected at the tube voltage proposed by the phantom study. The follow-up study confirmed the results from the phantom study that the reproduction of the carina was better at 90 than at 70 kV(p). In conclusion, for neonatal chest imaging-given the same effective dose-90 kVp gives better reproduction of important structures than the regularly used 70 kV(p).     

Chemical images

Chemical sensors can be used to generate a vast amount of information about the emissions from bio- and chemical processes, from food and bacteria and from a number of products. These emissions are either wanted or should be avoided. Wolfgang Göpel was one of those who recognized early the large potential of chemical sensor arrays and different modes of operation of a given sensor. We describe how large area field effect devices, with catalytic metal gates, can be used for the construction of a response image of a gaseous emission. More specifically, we discuss the new possibilities obtained through the use of catalytic metals with a gradient in thickness. Some basic features of such sensing surfaces are demonstrated and, finally, time-dependent response images from aging meat are used to demonstrate the potential of the method used. It is based on a scanning light pulse technique (SLPT) which measures local polarization or work function changes in two dimensions and, e.g. a sensing surface consisting of bands of different catalytic metals with a gradient in thickness.     

Upper Cretaceous–Cenozoic clay minerals of the Baikal region (eastern Siberia)

The Baikal region is located in a single climate zone and includes the Baikal foredeep on the eastern margin of the Siberian craton and the Baikal rift evolving at the western boundary of the Baikal orogenic area. Late Cretaceous–Cenozoic deposition in the two dissimilar tectonic units occurred in different environments, which is recorded in the architecture of sedimentary sequences and in the stratigraphic distribution of clay mineralogy.Clay minerals are mostly derived from weathered rocks of different ages. The geological ages of the source weathering mantles and their regular changes in different tectonic and climatic conditions can be inferred from the stratigraphic position in the Upper Cretaceous–Cenozoic sedimentary sequences that fill the Baikal foredeep. These inferences agree with data on fossil soils, flora, and fauna. Clay minerals show genetic relationships with stages of postdepositional alteration and processes of soil formation and hydrothermalism.In general, the Cenozoic history of erosion, deposition, and postdepositional changes of rocks in the Baikal region has been controlled by the interplay of climate and tectonic factors.     

A comparative performance study of common and popular task‐centric programming frameworks

Programmers today face a bewildering array of parallel programming models and tools, making it difficult to choose an appropriate one for each application. An increasingly popular programming model supporting structured parallel programming patterns in a portable and composable manner is the task‐centric programming model. In this study, we compare several popular task‐centric programming frameworks, including Cilk Plus, Threading Building Blocks, and various implementations of OpenMP 3.0. We have analyzed their performance on the Barcelona OpenMP Tasking Suite benchmark suite both on a 48‐core AMD Opteron 6172 server and a 64‐core TILEPro64 embedded many‐core processor. Our results show that the OpenMP offers the highest flexibility for programmers, and this flexibility comes to a cost. Frameworks supporting only a specific and more restrictive model, such as Cilk Plus and Threading Building Blocks, are generally more efficient both in terms of performance and energy consumption. However, Intel's implementation of OpenMP tasks performs the best and closest to the specialized run‐time systems. Copyright © 2013 John Wiley & Sons, Ltd.     

Theoretical models and experimental results on the temperature dependence of polyfluorene solar cells

The temperature dependence of device parameters of polymer solar cells based on alternating copolyfluorene incorporating dioctyl-fluorene and di-thienyl-benzothiadiazole (APFO-3) mixed with [6,6]-phenyl-C61-butyric acid methylester (PCBM) was modeled theoretically by simulation and investigated experimentally under illumination of AM1.5 (100 mW/cm²). Both simulation and experimental results show photocurrent, fill factor and power conversion efficiency all increase, and the open-circuit voltages monotonically decrease with temperature increase from room temperature (RT) to 120 °C. These results can be explained by taking into account the temperature dependence of the mobility, and the thermal activation of the injection current from the electrodes. The increase of PCE with temperature is a distinguishing feature of polymer solar cells.     

Visualisation and quantification of lung content of radionuclides associated with nuclear and radiological emergencies

In a situation when radionuclides accidentally or deliberately are dispersed in the environment, there is a need for rapid investigation of the internal contamination in exposed individuals. In this work, the possibilities of visualising and quantifying uptakes of different radionuclides in the lung region of an adult individual using gamma camera systems have been examined, mainly on a two-headed stationary clinical gamma camera. An anthropomorphic phantom was used to mimic acute lung uptakes in three different body sizes. The gamma camera was calibrated with the lung inserts filled with a homogeneous solution of ??Tc(m), ??Sc and 32P, or with point sources of 2?1Am, ??Co, ??Sr, 13?Cs and ??Sr/??Y. It was found that for the stationary gamma camera the minimum detectable activity in the lungs using a 5-min acquisition time ranged from 0.53 kBq for ??Sc to 50 kBq for 32P. Furthermore, the point sources of 13?Cs, ??Co and ??Sr/??Y (0.16, 0.80 and 2.2 MBq, respectively) located in the lung insert of the phantom, could be clearly visualised, exhibiting distinct intensity maxima. It is thus concluded that gamma camera systems can be useful for rapid assessment of acute intakes of radionuclides associated with emergency preparedness, both in terms of localisation and quantification.     

Shrunken Pore Syndrome Is Frequently Occurring in Severe COVID-19

A selective decrease in the renal filtration of larger molecules is attributed to the shrinkage of glomerular pores, a condition termed Shrunken Pore Syndrome (SPS). SPS is associated with poor long-term prognosis. We studied SPS as a risk marker in a cohort of patients with COVID-19 treated in an intensive care unit. SPS was defined as a ratio < 0.7 when the estimated glomerular filtration rate (eGFR), determined by cystatin C, calculated by the Cystatin C Caucasian-Asian-Pediatric-Adult equation (CAPA), was divided by the eGFR determined by creatinine, calculated by the revised Lund–Malmö creatinine equation (LMR). Clinical data were prospectively collected. In total, SPS was present in 86 (24%) of 352 patients with COVID-19 on ICU admission. Patients with SPS had a higher BMI, Simplified Physiology Score (SAPS3), and had diabetes and/or hypertension more frequently than patients without SPS. Ninety-nine patients in the total cohort were women, 50 of whom had SPS. In dexamethasone-naïve patients, C-reactive protein (CRP ), TNF-alpha, and interleukin-6 did not differ between SPS and non-SPS patients. Demographic factors (gender, BMI) and illness severity (SAPS3) were independent predictors of SPS. Age and dexamethasone treatment did not affect the frequency of SPS after adjustments for age, sex, BMI, and acute severity. SPS is frequent in severely ill COVID-19 patients. Female gender was associated with a higher proportion of SPS. Demographic factors and illness severity were independent predictors of SPS.