Applications like identifying different customers from their unique buying behaviours, determining ratingsof a product given by users based on different sets of features, etc. require classification using class-specific subsets of features. Most of the existing state-of-the-art classifiers for multivariate data use complete feature set for classification regardless of the different class labels. Decision tree classifier can produce class-wise subsets of features. However, none of these classifiers model the relationship between features which may enhance classification accuracy. We call the class-specific subsets of features and the features’ interrelationships as class signatures. In this work, we propose to map the original input space of multivariate data to the feature space characterized by connected graphs as graphs can easily model entities, their attributes, and relationships among attributes. Mostly, entities are modeled using graphs, where graphs occur naturally, for example, chemical compounds. However, graphs do not occur naturally in multivariate data. Thus, extracting class signatures from multivariate data is a challenging task. We propose some feature selection heuristics to obtain class-specific prominent subgraph signatures. We also propose two variants of class signatures based classifier namely: 1) maximum matching signature (gMM), and 2) score and size of matched signatures (gSM). The effectiveness of the proposed approach on real-world and synthetic datasets has been studied and compared with other established classifiers. Experimental results confirm the ascendancy of the proposed class signatures based classifier on most of the datasets. 相似文献
The network lifetime of Wireless Sensor Network (WSN) is one of the most challenging issues for any network protocol. The nodes in the network are densely deployed and are provided with limited power supply. The routing strategy is treated as an effective solution to improve the lifetime of the network. The cluster based routing techniques are used in the WSN to enhance the network lifespan and to minimize the energy consumption of the network. In this paper, an energy efficient heterogeneous clustering protocol for the enhancement of the network lifetime is proposed. The proposed protocol uses the sensor energy for the clustering process in a well-organized manner to maximize the lifetime of network. The MATLAB simulator is used for implementing the clustering model of proposed protocol and for measuring the effectiveness of the proposed technique the comparison is performed with the various existing approaches such as Stability Election Protocol, Distributed Energy Efficient Clustering and Adaptive Threshold Energy Efficient cross layer based Routing.
In this article, we propose the use of power function and least squares method for designing of a fractional order digital differentiator. The input signal is transformed into a power function by using Taylor series expansion, and its fractional derivative is computed using the Grunwald–Letnikov (G–L) definition. Next, the fractional order digital differentiator is modelled as a finite impulse response (FIR) system that yields fractional order derivative of the G–L type for a power function. The FIR system coefficients are obtained by using the least squares method. Two examples are used to demonstrate that the fractional derivative of the digital signals is computed by using the proposed technique. The results of the third and fourth examples reveal that the proposed technique gives superior performance in comparison with the existing techniques. 相似文献
We report fluctuation-induced conductivity (FIC) of the polycrystalline MgB2 superconductor in the presence of magnetic field. The results are described in terms of the temperature derivative of the resistivity, dρ/dT. The dρ/dT peak temperature observed for H = 0 Tesla at 39 K remains very distinct under applied fields of 6 Tesla and 8 Tesla at 22 and 20 K respectively. Aslamazov and Larkin (AL) equations are used to explain the anisotropic nature of the polycrystalline MgB2. The effective coherence length, ξp (0) determined experimentally is 55.17 Å, which roughly matches with previously reported experimental work. 相似文献
Gold nanoparticles (AuNPs) have exceptional stability against oxidation and therefore will play a significant role in the advancement of clinically useful diagnostic and therapeutic nanomedicines. Despite the huge potential for a new generation of AuNP-based nanomedicinal products, nontoxic AuNP constructs and formulations that can be readily administered site-specifically through the intravenous mode, for diagnostic imaging by computed tomography (CT) or for therapy via various modalities, are still rare. Herein, we report results encompassing: 1) the synthesis and stabilization of AuNPs within the nontoxic phytochemical gum-arabic matrix (GA-AuNPs); 2) detailed in vitro analysis and in vivo pharmacokinetics studies of GA-AuNPs in pigs to gain insight into the organ-specific localization of this new generation of AuNP vector, and 3) X-ray CT contrast measurements of GA-AuNP vectors for potential utility in molecular imaging. Our results demonstrate that naturally occurring GA can be used as a nontoxic phytochemical construct in the production of readily administrable biocompatible AuNPs for diagnostic and therapeutic applications in nanomedicine. 相似文献
Hepatitis C viral chemotherapy suffers from a relatively short half-life of the interferon alpha-2a (IFN alpha). To address this issue, we investigated the effects of polyethylene glycol modification and their subsequent encapsulation in multivesicular liposomes (MVLs), on the release properties of IFN alpha. In the present study, interferon-alpha was conjugated with methoxy-polyethylene glycol (mPEG, MW 5000). Prepared IFN alpha-mPEG5000 conjugate (IFN alpha-mPEG5000) was purified with size exclusion chromatography. The relative in vitro anti-viral activity of pegylated interferon alpha-2a was found to 87.9% of the unmodified IFN alpha. Pegylated IFN alpha encapsulated multivesicular liposomes were prepared by double emulsification technique followed by evaporation of organic solvents from chloroform ether spherules suspended in water. Prepared MVLs were then characterized for shape, size, vesicle count, encapsulation efficiency, and in vitro release rate. In process stability studies of pegylated IFN alpha protein exhibited better stability when exposed to chloroform: diethyl ether (1:1 ratio) mixture as well as variable vortexing time as compared to native IFN alpha. Relatively high percentage of encapsulation of protein ( approximately 75%) was achieved. In vitro release profile of pegylated IFN alpha-mPEG5000 containing MVLs in the PBS showed lower initial burst release with sustained and incomplete release over a period of 1 week. In contrast, native IFN alpha entrapped MVLs were observed as higher initial burst release, i.e., nearly 35% followed by almost complete release. The results confirmed the possibility of multivesicular liposomes as a long-acting or sustained-release delivery system using a combination of pegylation and encapsulation technique for controlled delivery of interferon alpha. 相似文献
Nanostructured multiphase Ti(C,N)/a-C films were deposited using a 3.3 kJ pulsed plasma focus device onto silicon (1 0 0) substrates at room temperature. The plasma focus device, fitted with solid titanium anode instead of usual hollow copper anode, was operated with nitrogen and Ar/CH4 as the filling gas. Films were deposited with different number of shots, at 80 mm from top of the anode and at zero angular position with respect to anode axis. X-ray diffraction results show the diffraction peaks related to different compounds such as TiC2, TiN, Ti2CN, Ti and TiC0.62 confirming the deposition of multiphase titanium carbo-nitride composite films on silicon. X-ray photoelectron spectroscopy confirms the formation of Ti–C, C–N, Ti–N, Ti–O and C–C bonds in the films. Scanning electron microscopy reveals that the nanostructure grains are agglomerates of smaller nanoparticles about 10–20 nm in size. Raman studies verify the formation of multiphase Ti(C,N) and also of amorphous graphite in the films. The maximum microhardness value of the composite film is 14.8 ± 1.3 GPa for 30 shots. 相似文献
The rural inhabitants of the Himalayan region have been exploiting forest resources for their livelihood for generations. The excessive and uncontrolled use of firewood for domestic purposes has ended up with severe deforestation. Therefore, quantification, assessment and restoration of such valuable but exhaustible resources and is imperative their scientific management. The estimates reflect that a total of 88 species are consumed as fuelwood (54 trees and 34 shrubs) by the local people. Fuelwood consumption by ‘dhaba’ (roadside refreshment establishments) owners (90–120 kg/household/day) was much higher over the common villagers (20–22 kg/household/day). The fuelwood is mainly burnt for cooking, water heating, space heating and lighting, etc. Among these, cooking consumes the fuelwood most. In addition, fuelwood demand increases due to influx of tourists. In the near future, this may also affect the status of the undisturbed forests at the middle elevation. The information in this communication could be utilized for developing various conservation and sustainable strategies in the region to mitigate the impact of forest resource for fodder and fuelwood. 相似文献
In this paper a 90 kJ plasma focus facility was used to the bombardment of the titanium substrate using nitrogen ion beams.
From x-ray diffraction patterns, we investigated the structure properties of titanium nitride layer has been successfully
deposited on the titanium substrate such as grain size microstrain and dislocation density. In this work we observed the growth
of in grain size with increasing a number of deposition shots. Decrease in dislocation density and microstrain at higher deposition
is the another results we observed in this work. The topography and morphology of TiN samples was studied by scanning electron
microscopy (SEM) and optical microscopy images. From SEM micrograph, damage of surface and creation of pits and cracks was
reported. The goniometric test indicate increasing in contact angle of water drop for irradiated samples in respect to the
unirradiated samples. The Knoop microhardness of the samples is increased about 500%. With increasing of nitrogen ion flux,
the microhardness increases. 相似文献