Simplifying CE-MS operation. 2. Interfacing low-flow separation techniques to mass spectrometry using a porous tip

A robust, reproducible, and single-step interface design between low flow rate separation techniques, such as sheathless capillary electrophoresis (CE) and nanoliquid chromatography (nLC), and mass spectrometry (MS) using electrospray ionization (ESI), is introduced. In this design, the electrical connection to the capillary outlet was achieved through a porous tip at the capillary outlet. The porous section was created by removing 1-1.5 in. of the polyimide coating of the capillary and etching this section by 49% solution of HF until it is porous. The electrical connection to the capillary outlet is achieved simply by inserting the capillary outlet containing the porous tip into the existing ESI needle (metal sheath) and filling the needle with the background electrolyte. Redox reactions of water at the ESI needle and transport of these small ions through the porous tip into the capillary provides the electrical connection for the ESI and for the CE outlet electrode. The etching process reduces the wall thickness of the etched section, including the tip of the capillary, to 5-10 microm, which for a 20-30 microm i.d. capillary results in stable electrospray at approximately 1.5 kV. The design is suitable for interfacing a wide range of capillary sizes with a wide range of flow rates to MS via ESI, but it is especially useful for interfacing narrow (<30 microm i.d.) capillaries and low flow rates (<100 nL/min). The advantages of the porous tip design include the following: (1) its fabrication is reproducible, can be automated, and does not require any mechanical tools. (2) The etching process reduces the tip outer diameter and makes the capillary porous in one step. (3) The interface can be used for both nLC-MS and CE-MS. (4) If blocked or damaged, a small section of the tip can be etched off without any loss of performance. (5) The interface design leaves the capillary inner wall intact and, therefore, does not add any dead volume to the CE-MS or nLC-MS interface. (6) Bubble formation due to redox reactions of water at the high-voltage electrode is outside of the separation capillary and does not affect separation or MS performances. The performance of this interface is demonstrated by the analyses of amino acids, peptide, and protein mixtures.     

Combination of neural network and wavelet transform for islanding detection of distributed generation in a small-scale network

In this paper, an optimum and intelligent method is proposed for islanding detection using wavelet transform. The suggested relay is based on neural network (NN) in which different heuristic algorithms are used for training the NN. In the proposed method, the appropriate signals for detection procedure as well as mother wavelet are selected optimally, based on the mean square error (MSE) concept. Lately, the desired relay is trained by the optimally selected signals using four different algorithms and the optimum condition of the fault detector is identified. Simulation results approved that non detection zone (NDZ) has a significant reduction utilising the proposed intelligent technique. The contributions of the proposed method include presenting an appropriate signal selection method based on MSE, selecting optimum number of relay input signals using the proposed technique, fast training of intelligent relay by using least information, solving threshold selection problem and reduction of NDZ approximately to zero.     

Multiobjective optimal placement of active tendons to control irregular multistory buildings with soil–structure interaction

In recent decades, many researchers have conducted research studies on structural control to improve the safety and serviceability of high‐rise buildings against earthquakes and strong winds. On the other hand, applying active control systems and controlling strategies in buildings are costly process, and it is necessary to reduce the number of controllers. In this paper, a multiobjective genetic algorithm is proposed to optimize the placement of active tendons in a 2D shear frame and a 3D irregular building considering soil–structure interaction effect to reduce active control cost and response of structures at the same time. For multiobjective optimization, multiobjective genetic algorithm of the MATLAB toolbox is used to find a set of Pareto optimal solutions for a multiobjective minimization. The results indicate that the method is capable of finding the number and location of the required active tendons in both 2D shear frame and 3D irregular building with 10 and 20 stories while the base shear of structure is minimized. The specific advantage of the employed algorithms is to reduce the number of mounted active tendons approximately by 50%.     

Thermochemical,Sensitivity and Detonation Characteristics of New Thermally Stable High Performance Explosives

The M06‐2X/6‐311G(d,p) and B3LYP/6‐311G(d,p) density functional methods and electrostatic potential analysis were used for calculation of enthalpy of sublimation, crystal density and enthalpy of formation of some thermally stable explosives in the gas and solid phases. These data were used for prediction of their detonation properties including heat of detonation, detonation pressure, detonation velocity, detonation temperature, electric spark sensitivity, impact sensitivity and deflagration temperature using appropriate methods. The range of different properties for these compounds are: crystal density 1.51–2.01 g cm⁻³, enthalpy of sublimation 346.4–424.7 kJ mol⁻¹, the solid phase enthalpy of formation 500.4–860.6 kJ mol⁻¹, heat of detonation 13.64–17.57 kJ g⁻¹, detonation pressure 33.0–37.0 GPa, detonation velocity 8.5–9.5 km s⁻¹, detonation temperature 5488–6234 K, electric spark sensitivity 7.89–9.47 J, impact sensitivity 21–38 J, deflagration temperature 560–586 K and power [%TNT] 207–276. The results show that two novel energetic compounds N,N′‐(diazene‐1,2‐diylbis(2,3,5,6‐tetranitro‐4,1‐phenylene))bis(5‐nitro‐4H‐1,2,4‐triazol‐3‐amine) (DDTNPNT3A) and 1,1′‐(diazene‐1,2‐diylbis(2,3,5,6‐tetranitro‐4,1‐phenylene))bis(3‐nitro‐1H‐1,2,4‐triazol‐5‐amine) (DDTNPNT5A) can be introduced as thermally explosives with high detonation performance.     

Hydrogeochemistry and Contamination of Trace Elements in Cu-Porphyry Mine Tailings: A Case Study from the Sarcheshmeh Mine,SE Iran

Geochemical and hydrochemical investigations were performed to understand the contamination potential of the Sarcheshmeh mine tailings. The geochemical mobility for the tailings is as follows: Cu > Cd > Co > Zn > Ni > Mn > S > Cr > Sn > As > Se > Fe = Bi > Sb = Pb = Mo. Highly mobile and contaminant elements (Cd, Cu, Zn, Mn, Co, Ni, S, and Cr), which significantly correlated with each other, were mainly concentrated in the surface evaporative layer of the old, weathered tailings, due to the high evaporation rate, which causes subsurface water to migrate upward via capillary action. The contamination potential associated with the tailings is controlled by: (1) dissolution of secondary evaporative soluble phases, especially after rainfall on the old weathered tailings, accompanied by low pH and high contamination loads of Al, Cd, Co, Mg, Cr, Cu, Mn, Ni, S, Se, and Zn; (2) processing of the Cu-porphyry ore under alkaline conditions, which is responsible for the high Mo (mean of 2.55 mg/L) and very low values of other contaminants in fresh tailings in the decantation pond; (3) low mobility of As, Fe, Pb, Sb, Mo, and Sn due to natural adsorption and co-precipitation in the tailings oxidizing zone. Speciation modeling showed that sulfate complexes (MSO₄ ⁺, M(SO₄)_(aq), M(SO₄) ₂ ^?2 , and M(SO₄) ₂ ^? ) and free metal species (M⁺² and M⁺³) are the dominant forms of dissolved cations in the acidic waters associated with the weathered tailings. In the alkaline and highly alkaline waters, trace element speciation was controlled by various hydroxide complexes, such as M(OH)⁺, M(OH) ₃ ^? , M₃(OH) ₄ ⁺² , M₂(OH) ₃ ⁺ , M(OH)_2(aq), M(OH) ₄ ^?2 , Me(OH) ₂ ⁺ , Me(OH) ₄ ^? , Me(OH) ₂ ⁺ , Me(OH)_3(aq), and Me(OH) ₄ ^? (where M represents bivalent and Me represents trivalent cations). The speciation pattern of As, Mo, and Se is mainly dominated by oxy-anion forms. The obtained results can be used as a basis for environmental management of the Cu-porphyry mine tailings.     

Hot Deformation Behavior of Beta Titanium Ti-13V-11Cr-3Al Alloy

Hot compression tests were conducted on Ti-13V-11Cr-3Al beta-Ti alloy in the temperature range of 1203 K to 1353 K (930 °C to 1080 °C) and at strain rates between 0.001 and 1 s^?1 The stress–strain curves showed pronounced yield point phenomena at high strain rates and low temperatures. The yield point elongation and flow stresses at the upper and lower yield points were related to the Zener–Hollomon parameter. It was found that dynamic recovery at low strain rates and dynamic recrystallization at high strain rates were the controlling mechanisms of microstructural evolution. The results also showed that strain rate had a stronger influence on the hot deformation behavior than temperature. The microstructural observations and constitutive analysis of flow stress data supported the change in the hot deformation behavior of the studied alloy varies with strain rate. For various applied strain rates, the activation energy for hot deformation was calculated in range of 199.5 to 361.7 kJ/mol. At low strain rates (0.001 and 0.01 s^?1), the value of activation energy was very close to the activation energy for the diffusion of V, Cr, and Al in beta titanium. The higher value of activation energy for deformation at high strain rates (0.1 and 1 s^?1) was attributed to the accumulation of dislocations and the tendency to initiate dynamic recrystallization.     

STUDY OF MIXED-CONVECTION HEAT TRANSFER FROM AN IMPINGING JET TO A SOLID WALL USING A FINITE-ELEMENT METHOD—APPLICATION TO COOKTOP MODELING

The mixed-convection flow from a hot vertical impinging jet on a colder horizontal disc has been studied. The geometry is analogous to a conventional burning gas cooktop. A numerical simulation of the system has been carried out using the finite-element method to study the dependence of fluid flow and heat transfer on the geometric, thermal, and fluid flow parameters. Results show that heat transfer efficiency versus several parameters such as inlet velocity magnitude and flue gas temperature has an optimum value, in which heat transfer efficiency is maximum. With thermal conductivity of the solid wall, velocity angle, and solid wall diameter heat transfer efficiency has increasing behavior. Finally, with solid wall height and solid wall thickness, heat transfer efficiency has diminishing behavior.     

Immersed boundary method for the simulation of heat transfer and fluid flow based on vorticity–velocity formulation

ABSTRACT

The present paper, based on the vorticity–velocity formulation of the Navier–Stokes equations, proposes an immersed boundary method for the simulation of heat transfer problems within a geometrically complex domain. The desired boundary conditions are imposed by the direct modification of the initial conditions of vorticity transport and energy equations using smooth interpolations. The time advancement of both transport equations is performed by the explicit fourth-order Runge–Kutta method. One of the main objectives of this paper is to present global smooth interpolations to evaluate the local Nusselt number. The forced convection of moving and fixed circular cylinders, natural convection problem in complex geometries, and the mixed convection between two concentric cylinders—at various Reynolds numbers—are studied.     

A Review of Heat Transfer and Pressure Drop Correlations for Laminar Flow in Curved Circular Ducts

Heat transfer and pressure drop correlations for fully developed laminar Newtonian fluid flow in curved and coiled circular tubes are reviewed. Curved geometry is one of the passive heat transfer enhancement methods that fits several heat transfer applications, such as power production, chemical and food industries, electronics, environment engineering, and so on. Centrifugal force generates a pair or two pairs of cross-sectional secondary flow (based on the Dean number), which are known as the Dean vortices, and improves the overall heat transfer performance with an amplified peripheral Nusselt number variation. The main purpose of this review paper is to provide researchers with a comprehensive list of correlations and concepts that they may need during their research. The paper begins with an introduction to the governing equations and important dimensionless numbers for the flow in curved tubes. The correlations for developing flow in curved and coiled circular tubes are also presented. The main contribution of this study is reviewing the numerical and experimental correlations to calculate friction factor and Nusselt number in curved circular tubes. Nusselt number correlations are categorized based on the thermal boundary condition, as well as on the method. A Dean number range of 1 to 20,000 for the pressure drop correlations and 1 to 7000 for the heat transfer correlations and a Prandtl number range of 0.1 to 7,000 are covered with the reviewed correlations.     

A Numerical Study on Natural Convention Heat Transfer From a Horizontal Isothermal Cylinder Located Underneath an Adiabatic Ceiling

A numerical analysis is performed for steady-state and two-dimensional natural convection heat transfer from a horizontal isothermal cylinder located underneath a horizontal adiabatic ceiling. The finite-volume method based on the SIMPLE algorithm and a nonorthogonal grid discretization scheme are used to solve the continuity, momentum, and energy equations for the Rayleigh numbers in the range from 10^?1 to 10⁴. The Poisson equations are solved to find the grid points, which are distributed in a nonuniform manner with higher concentration close to the solid regions. In addition, the HYBRID differencing scheme is used for the approximation of the convective terms in the curvilinear coordinate. The effects of the Rayleigh numbers and cylinder spacing from the adiabatic ceiling on both the local and average Nusselt numbers around the cylinder are investigated. Numerical results are performed for the plate-to-cylinder spacing ranging from 0.1 to 1.4.