The APOA5-rs662799 Polymorphism Is a Determinant of Dyslipidemia in Vietnamese Primary School Children

Apolipoprotein A-V encoded by apolipoprotein 5 (APOA5) gene plays an important role in lipid metabolism, especially in the regulation of plasma triglycerol levels. The study aimed to evaluate the association of the APOA5-rs662799 polymorphism with dyslipidemia in Vietnamese children and the potential modification of obesity-related traits (body mass index, waist circumference, hip circumference, and waist-to-hip ratio) on this association. A case–control study was conducted with a total of 154 dyslipidemia cases and 389 controls at the age of 6 to 10 recruited at 31 primary schools in Hanoi city of Vietnam. Genotype for APOA5-rs662799 polymorphism was determined by the restriction fragment length polymorphism analysis. The association of APOA5-rs662799 polymorphism with dyslipidemia adjusting for age, sex, residence, and obesity-related traits was analyzed by binary logistic regression analysis. The results showed that in comparison with T/T and T/C carriers, the C/C carriers had a higher concentration of serum TAG in cases (p =0.049). Carriers of the C allele (C/C + T/C) had higher risk for developing dyslipidemia and hypertriglyceridemia than subjects with T/T genotype (odds ratio, OR = 1.7, p =0.0062 and OR = 1.6, p = 0.026, respectively). The association remained significant after adjusting for age, gender, residence, and obesity status (OR = 1.75, p = 0.006 and OR = 1.53, p = 0.049, respectively) or other obesity-related traits. The study suggested that the APOA5-rs662799 polymorphism may be a determinant of dyslipidemia and hypertriglyceridemia in Vietnamese children, independent of obesity-related traits.     

Photocatalytic degradation and heat reflectance recovery of waterborne acrylic polymer/ZnO nanocomposite coating

This work aims to clarify the photocatalytic degradation mechanism and heat reflectance recovery performance of waterborne acrylic polymer/ZnO nanocomposite coating. To fabricate the nanocomposite coating, ZnO nanoparticles (nano-ZnO) were dispersed into acrylic polymer matrix at the various concentrations from 1 to 6% (by total weight of resin solids). The photocatalytic degradation of nanocomposite coating under ultraviolet (UV) light irradiation has been investigated by monitoring its weight loss and chemical/microstructural/morphological changes. As the topcoat layer, its heat reflectance recovery has been evaluated under UV/condensation exposure by using an artificial dirty mixture of 85 wt% nanoclay, 10 wt% silica particles (1–5 μm), 1 wt% carbon black, and 2 wt% engine oil. After 108-cycle UV/condensation exposure, infrared spectra and weight loss analysis indicated that the maximal degradation for nanocomposite coating is observed at 1 wt% nano-ZnO. On the other hand, after 96 hr of UV light exposure, the nanocomposite coating with1 wt% nano-ZnO could restore effectively the reflective index of solar-heat reflectance coating (from 58.45 to 80.78%). Finally, the photodegradation mechanism of this waterborne acrylic polymer coating has been proposed as the UV-induced formation of CC CO conjugated double bonds. As a result, its self-cleaning phenomenon can be achieved as the recovery of heat reflectance.     

Advanced Surface of Fibrous Activated Carbon Immobilized with FeO/TiO2 for Photocatalytic Evolution of Hydrogen under Visible Light

FeO-doped TiO₂ nanoparticle photocatalysts were immobilized onto the surface of fibrous activated carbon (ACF) via a sol-gel process. As an adsorbent and photocatalyst, FeO-TiO₂ on immobilized ACFs (FeO-TiO₂/ACF) greatly improved the photocatalysis rate of hydrogen production as compared with pure TiO₂ and ACF-TiO₂ under UV irradiation and visible light. The addition of ACFs surface significantly reduced the photogenerated pairs of electrons-hole recombination, thereby promoting the photocatalysis action of doped photo-metal oxides of FeO-TiO₂. Co-doping of FeO onto the lattice of the TiO₂ approach can improve the absorption activity of visible light through photo-metal oxide of TiO₂ and further enhance hydrogen production under visible light. The photocatalytic fabrics (FeO-TiO₂/ACF) were effortlessly split out from the experimental solution for re-utilization and exhibited high stability even after five complete regeneration cycles.     

Photocrosslinking of functionalized rubbers. X. Butadiene–acrylonitrile copolymers

The photocrosslinking of polyacrylonitrile‐block‐polybutadiene‐block‐polyacrylonitrile (ABA) was shown to proceed within seconds at ambient temperature upon UV exposure in the presence of an acylphosphine oxide photoinitiator. The curing process was followed by infrared spectroscopy, insolubilization, and hardness measurements. Complete insolubilization could not be achieved with the neat ABA rubber because of the poor reactivity of the 2‐butene double bond and the low vinyl content of the polybutadiene chain. The addition of multifunctional acrylate monomers (20 wt %) causes a substantial increase of both the reaction rate and the crosslink density of the polymer, which becomes completely insoluble in toluene in less than 1 s upon UV irradiation. An even greater effect was observed by using small amounts (1 wt %) of a trifunctional thiol crosslinker. Both the thiol and the photoinitiator concentrations were shown to affect the kinetics of the thiol–ene polymerization and the polymer network crosslink density. A direct relationship was found to exist between the swelling degree of the UV‐cured rubber and the interchain molecular weight of the network. © 2001 John Wiley & Sons, Inc. J Appl Polym Sci 82: 2204–2216, 2001     

稻壳制备活性炭联产二氧化硅工艺

采用物理法将稻壳炭化,炭化料用酸碱处理,固体残渣经高温水蒸汽活化制备活性炭,脱灰液体采用沉淀法制备SiO2. 结果表明,用2.5 mol/L NaOH溶液按液固比10 mL/g脱灰的炭化料所制活性炭比表面积为961.8 m2/g,比不脱灰炭化料所制活性炭增加136%,总孔容积增加103.8%,对碘和亚甲基蓝的吸附容量分别为1270和300 mg/g. 在10% HCl、煅烧温度600℃条件下所制SiO2粒径为40~60 nm,为无定型结构,比表面积达330 m2/g,纯度达99.84%.     

Effect of Temperature on Oxidation Behavior of 3‐Dimensional C/SiC Composites Coated by Different Structural SiC and a‐BCx Coatings in Static Wet Oxygen Atmosphere

The effect of temperature on oxidation behavior of 3‐dimensional C/SiC composites coated with SiC and a‐BC_x coatings was investigated. Below 1000°C, C/SiC composites with SiC coating (sample SSS) showed low residual strength, while the composites with a‐BC_x coating (sample BBB) and the composites with a‐BC_x/a‐BC_x/SiC coatings (sample BBS) showed high residual strength. Above 1000°C, samples SSS and BBS showed high residual strength, while sample BBB showed the opposite results. Sample BBS presented better oxidation resistance during 700–1200°C. The oxidation temperature made an effect on self‐sealing mode of sample BBS.     

Synthesis of urea-pyridyl ligand functionalized mesoporous silica hybrid material for hydrophobic and hydrophilic drug delivery application

In this work, we propose the synthesis of urea-pyridyl (UPy) ligand functionalized mesoporous silica hybrid material as novel and effective drug delivery system for loading/release of both hydrophobic and hydrophilic drugs. For the synthesis of UPy ligand functionalized mesoporous silica hybrid material, the combination of sol–gel co-condensation technique and post silica surface modification method were adapted. The prepared UPy ligand functionalized mesoporous silica hybrid (UPy-MSH) material was characterized by X-ray diffraction, Fourier-transform infrared, N₂ adsorption–desorption analysis. The material morphology and mesopore channels were observed by scanning and transmission electron microscopic analyses. The content of modified organic ligand functionalities present in the UPy-MSH material surface was determined by thermogravimetric analysis. The hydrophilic anticancer drug, 5-Fluorouracil and the hydrophobic anti-inflammatory drug, Ibuprofen was used as a model drugs to determine the loading and pH-responsive release efficiency of the synthesized UPy-MSH material under different pH (pH 7.4 and 5.0) conditions, respectively. In addition, the biocompatibility of the UPy-MSH material was evaluated on MDA-MB-231 cells. The experimental results depicted that the synthesized UPy-MSH material is biocompatible and has high drug loading capacity, selective and controlled release of specific drug with respect to the pH condition.