Indoor Ad Hoc Proximity-Location Sensing for Service Provider Selection

There are protocols that can be used by mobile clients to discover service providers in foreign networks to which they get attached, e.g., SDP of Bluetooth and SLP of IETF. These protocols do address service discovery, but do not address the selection of a service provider among a set of candidates according to a physical proximity of the client and service provider. The goal of the research described in this paper is to integrate proximity-based selection mechanisms to service discovery protocols. We present in this paper protocols that allow nomadic clients to discover and select service providers according to physical proximity.     

Synchronous tabu search parallelization strategies for multicommodity location-allocation with balancing requirements

We study and compare synchronous parallelization strategies for tabu search. We identify the most promising parallelization approaches, and evaluate the impact on performance and solution quality of some important algorithmic design parameters: length of the synchronization steps, number of processors, handling of exchanged information, etc. Parallelization approaches are implemented and compared by using a tabu search algorithm for multicommodity location-allocation problems with balancing requirements.     

Influence of genotype on the clinical course of the long-QT syndrome. International Long-QT Syndrome Registry Research Group

BACKGROUND: The congenital long-QT syndrome, caused by mutations in cardiac potassium-channel genes (KVLQT1 at the LQT1 locus and HERG at the LQT2 locus) and the sodium-channel gene (SCN5A at the LQT3 locus), has distinct repolarization patterns on electrocardiography, but it is not known whether the genotype influences the clinical course of the disease. METHODS: We determined the genotypes of 541 of 1378 members of 38 families enrolled in the International Long-QT Syndrome Registry: 112 had mutations at the LQT1 locus, 72 had mutations at the LQT2 locus, and 62 had mutations at the LQT3 locus. We determined the cumulative probability and lethality of cardiac events (syncope, aborted cardiac arrest, or sudden death) occurring from birth through the age of 40 years according to genotype in the 246 gene carriers and in all 1378 members of the families studied. RESULTS: The frequency of cardiac events was higher among subjects with mutations at the LQT1 locus (63 percent) or the LQT2 locus (46 percent) than among subjects with mutations at the LQT3 locus (18 percent) (P<0.001 for the comparison of all three groups). In a multivariate Cox analysis, the genotype and the QT interval corrected for heart rate were significant independent predictors of a first cardiac event. The cumulative mortality through the age of 40 among members of the three groups of families studied was similar; however, the likelihood of dying during a cardiac event was significantly higher (P<0.001) among families with mutations at the LQT3 locus (20 percent) than among those with mutations at the LQT1 locus (4 percent) or the LQT2 locus (4 percent). CONCLUSIONS: The genotype of the long-QT syndrome influences the clinical course. The risk of cardiac events is significantly higher among subjects with mutations at the LQT1 or LQT2 locus than among those with mutations at the LQT3 locus. Although cumulative mortality is similar regardless of the genotype, the percentage of cardiac events that are lethal is significantly higher in families with mutations at the LQT3 locus.     

Centralized and decentralized stochastic routing models in telecommunication networks

With the advent of non-hierarchical routing in circuit-switched telecommunication networks, on-line routing policies have been developed with the objective of optimizing some measure of gain or performance. These policies are decentralized. However, traditional planning models are centralized models. We present a decentralized routing model to be used in network planning. We compare it theoretically and empirically with a centralized multicommodity flow model previously presented. The two models are solved by the same type of algorithm, a convex simplex implementation, adapted differently according to the model. Comparative results between planning models reproducing the two policies are discussed.     

Formulation of a new intergranular creep damage model for austenitic stainless steels

The aim of this study is to propose a physically based intergranular creep damage model for numerical simulations on extrapolated situations. A continuum damage formulation is proposed to evaluate nucleation, growth and coalescence of intergranular creep cavities. Nucleation is based on an empirical law where void fraction growth rate is proportional to the creep strain rate. Void growth rate includes the contribution of: viscoplastic strain rate of surrounding grains (Gurson), and vacancy diffusion along grain boundaries (Hull and Rimmer). Void coalescence is based on a mechanical fracture criterion, where the competition between damage softening and viscoplastic hardening is considered. The identification procedure needs only the results of uniaxial creep tensile tests with a range of time to rupture that enables a sufficient diffusion contribution. The constraint effect is taken into account in the formulation of the model and does not need a specific identification. To illustrate the capacity of the proposed model, applications are presented for an austenitic stainless steel tested at 600 °C. It appears that the constraint effect assessment is in good agreement with experimental results, when we compare time to rupture and intergranular damage localisation on notched specimens, or crack initiation time and crack growth rate on fatigue pre-cracked specimens.     

Determination of volatile compounds to characterize fish spoilage using headspace/mass spectrometry and solid‐phase microextraction/gas chromatography/mass spectrometry

Changes in volatile compounds were monitored in whiting (Merlangius merlangus), cod (Gadus morhua) and mackerel (Scomber scombrus) and related to spoilage. Data are presented from headspace/mass spectrometric (HS/MS) analysis and solid‐phase microextraction/gas chromatographic/mass spectrometric (SPME/GC/MS) analysis at two time points (day 0 and day 10) during storage at 4 °C. HS/MS revealed 24 ions that could be used as markers of spoilage. SPME/GC/MS identified 86 compounds, 20 of which could perhaps be used to characterize freshness: principally alcohols, ketones, aldehydes and C₂–C₁₁ esters. Compounds common to the three species studied appear to be generated by microbial degradation. Copyright © 2005 Society of Chemical Industry     

FE modeling of Lamb mode diffraction by defects in anisotropic viscoelastic plates

A Finite Element code is used in a stationary mode to compute, at a single frequency, the stress and displacement fields in plates made of anisotropic, viscoelastic materials. An appropriated spatial load at one boundary of the plate is applied to generate a guided mode. This step is included in a frequency loop for which the number of iterations (≈ usually less than 50) is defined by the frequency spectrum of a temporal excitation. Then the temporal response at any location in the plate can be reconstructed with inverse Fourier transform. The phase velocity, attenuation and nature of one or several propagating modes can be identified in the classical frequency/wave number representation. The first example concerns the interaction of the symmetric Lamb mode S₀ with an opening notch in a Perspex plate. The proportion of S₀ and converted antisymmetric A₀ mode, transmitted past the notch is evaluated by the FE method and validated by a comparison with measurements made on a real system using an air coupled transducer. The second example shows the effect of the viscoelasticity on the propagation of the symmetric Lamb mode S₀ in a cross-ply, carbon-epoxy material plate. Focus is made on some difficulties that the attenuation causes on the detection of a delamination between plies.     

Long-term functional outcome following transient middle cerebral artery occlusion in the rat: Correlation between brain damage and behavioral impairment.

The assessment of both histological and functional long-term outcomes after cerebral ischemia is increasingly recommended for preclinical studies. Whereas correlations between behavioral impairments and primary ischemic lesion are documented, little is known about their relationships with remote nonischemic regions that undergo secondary degeneration, such as the thalamus. Anesthetized rats were subjected to mild (30 min) or severe (60 min) occlusion of the middle cerebral artery. Two months after ischemia, sensorimotor behavior was assessed according to the neurological score, limb-placing, adhesive-removal, and staircase tests; the final histological lesion was measured after this assessment. Cortical damage was correlated to all transient and long-lasting sensorimotor deficits, whereas striatal lesion was more consistently reflected by the forelimb-placing reflexes and adhesive-removal motor deficits. By contrast, the thalamic atrophy was not correlated to early neurological impairment, but rather to the late sensory deficit at the adhesive-removal test and to the skilled forepaw reaching alteration at the staircase test. This suggests that thalamus contributes, albeit moderately, to the ischemia-induced long-lasting sensorimotor deficits, some of which represent relevant targets for therapeutic interventions. (PsycINFO Database Record (c) 2010 APA, all rights reserved)