全文获取类型
收费全文 | 222篇 |
免费 | 11篇 |
专业分类
电工技术 | 7篇 |
化学工业 | 78篇 |
金属工艺 | 7篇 |
机械仪表 | 3篇 |
建筑科学 | 8篇 |
能源动力 | 10篇 |
轻工业 | 26篇 |
石油天然气 | 2篇 |
无线电 | 18篇 |
一般工业技术 | 26篇 |
冶金工业 | 26篇 |
原子能技术 | 4篇 |
自动化技术 | 18篇 |
出版年
2022年 | 6篇 |
2021年 | 7篇 |
2020年 | 2篇 |
2019年 | 1篇 |
2018年 | 4篇 |
2017年 | 4篇 |
2016年 | 7篇 |
2015年 | 2篇 |
2014年 | 10篇 |
2013年 | 7篇 |
2012年 | 7篇 |
2011年 | 13篇 |
2010年 | 7篇 |
2009年 | 15篇 |
2008年 | 10篇 |
2007年 | 11篇 |
2006年 | 2篇 |
2005年 | 3篇 |
2004年 | 8篇 |
2003年 | 9篇 |
2002年 | 4篇 |
2001年 | 7篇 |
2000年 | 4篇 |
1999年 | 10篇 |
1998年 | 14篇 |
1997年 | 9篇 |
1996年 | 9篇 |
1995年 | 6篇 |
1994年 | 4篇 |
1993年 | 2篇 |
1992年 | 3篇 |
1991年 | 3篇 |
1990年 | 3篇 |
1989年 | 3篇 |
1988年 | 2篇 |
1987年 | 2篇 |
1985年 | 2篇 |
1984年 | 1篇 |
1983年 | 4篇 |
1981年 | 1篇 |
1980年 | 1篇 |
1978年 | 1篇 |
1976年 | 2篇 |
1971年 | 1篇 |
排序方式: 共有233条查询结果,搜索用时 31 毫秒
231.
Koichiro Hayashi Michihiro Nakamura Hirokazu Miki Shuji Ozaki Masahiro Abe Toshio Matsumoto Kazunori Ishimura 《Advanced functional materials》2012,22(17):3539-3546
Ring‐shaped silica nanoparticles are synthesized with a high tetrakis(4‐carboxyphenyl)porphyrin (TCPP) content or silica/TCPP hybrid nanorings (HNRs) using a one‐pot sol‐gel reaction with a TCPP‐binding silica precursor for fluorescence imaging of tumor. The shape of the HNRs is a reflection of abundant ring‐shaped TCPP aggregates in the silica matrix. The HNRs are of a size that makes them susceptible to the enhanced permeability and retention effect. For comparison, the TCPP‐doped silica nanoparticles are synthesized using a conventional method. The nanoparticles are spherical in shape because little TCPP is contained in the silica matrix and are designated as TCPP‐containing silica nanospheres (NSs). The absorption bands of the HNRs shift by about 20 nm toward longer wavelengths compared with the TCPP bands. This redshift leads the excitation wavelength of the HNRs into the near‐infrared (NIR) region. Therefore, the HNRs are excited by NIR light to emit strong fluorescence, although the NSs emit no fluorescence. The PEGylated HNRs (PEG‐HNRs) are uncharged and possess a significantly longer blood circulation time than PEG‐NSs. The PEG‐HNRs accumulate in tumor through multiple factors including their size, uncharged surface, unique shape, and long circulation time in blood, resulting in the acquisition of clear images of tumor. 相似文献
232.
Lymphatic transport of a mixture of medium-chain TAG (MCT) and long-chain TAG (LCT) was studied in lymph-cannulated rats.
Animals were administered a test emulsion containing either triolein, tricaprylin, or a 1∶1 mixture of triolein and tricaprylin,
and the lymph was collected for 24 h. The lymphatic recovery rate of medium-chain FA (MCFA) was significantly higher in rats
given the TAG mixture than in those given MCT alone. The lymphatic recovery rate of long-chain FA (LCFA) also was significantly
higher in rats given the TAG mixture than in those given LCT alone. No TAG containing three MCFA (i.e., MCT) was detected,
and 37.7% of TAG containing one or two MCFA was detected in the lymph TAG when rats were given the TAG mixture. These results
indicate that lymphatic transport of MCFA and LCFA can be modified by the combination of MCT and LCT. 相似文献
233.
Takaomi Kessoku Takashi Kobayashi Kosuke Tanaka Atsushi Yamamoto Kota Takahashi Michihiro Iwaki Anna Ozaki Yuki Kasai Asako Nogami Yasushi Honda Yuji Ogawa Shingo Kato Kento Imajo Takuma Higurashi Kunihiro Hosono Masato Yoneda Haruki Usuda Koichiro Wada Satoru Saito Atsushi Nakajima 《International journal of molecular sciences》2021,22(15)
The liver directly accepts blood from the gut and is, therefore, exposed to intestinal bacteria. Recent studies have demonstrated a relationship between gut bacteria and nonalcoholic fatty liver disease (NAFLD). Approximately 10–20% of NAFLD patients develop nonalcoholic steatohepatitis (NASH), and endotoxins produced by Gram-negative bacilli may be involved in NAFLD pathogenesis. NAFLD hyperendotoxicemia has intestinal and hepatic factors. The intestinal factors include impaired intestinal barrier function (leaky gut syndrome) and dysbiosis due to increased abundance of ethanol-producing bacteria, which can change endogenous alcohol concentrations. The hepatic factors include hyperleptinemia, which is associated with an excessive response to endotoxins, leading to intrahepatic inflammation and fibrosis. Clinically, the relationship between gut bacteria and NAFLD has been targeted in some randomized controlled trials of probiotics and other agents, but the results have been inconsistent. A recent randomized, placebo-controlled study explored the utility of lubiprostone, a treatment for constipation, in restoring intestinal barrier function and improving the outcomes of NAFLD patients, marking a new phase in the development of novel therapies targeting the intestinal barrier. This review summarizes recent data from studies in animal models and randomized clinical trials on the role of the gut–liver axis in NAFLD pathogenesis and progression. 相似文献