Correction to: Uniform and scalable sampling of highly configurable systems

Empirical Software Engineering - Testing Internet of Things (IoT) systems is challenging. This is not only because of the various aspects of IoT systems, such as software, hardware, and network...     

A Cubic Silsesquioxane Chemically Modified with a PAMAM Dendrimer G0: an Application in Electro-Oxidation of Ascorbic Acid

Silicon - Octa-(3-chloropropyl) octasilsesquioxane (SS) was functionalized with a PAMAM dendrimer (SP) and characterized by some spectroscopic techniques such as Fourier Transform Infrared, Nuclear...     

Nanostructured micronized solid dispersion of crystalline-amorphous metronidazole embedded in amorphous polymer matrix prepared by nano spray drying

In this study metronidazole drug was encapsulated by hydroxypropyl methylcellulose and polyvinylpyrrolidone polymers from solutions using nano spray drying technology. The influence of the process parameters and formulation variables were investigated on product morhology and structure, production yield and entrapment efficiency. The use of surface active admixtures (polyvinyl alcohol, Tween-80 and Pluronic F68) increased the product yield substantially. The entrapped metronidazole was partially in crystalline and amorphous state in both amorphous polymers as confirmed by DSC and powder X-ray diffraction measurements. In the composites with hydroxypropyl methylcellulose the degree of crystallinity was between 50.2 and 81.0%, and with polyvinylpyrrolidone between 35.0 and 50.0% (with respect to the drug content). Melting point decrease phenomena was observed by differential scanning calorimetry between bulk metronidazole and spray dried products. Peak broadening was indicated by powder X-ray diffraction measurements, which could be the result of formation of small drug crystallites. The TEM images showed beside the larger crystals (200–400 nm) a fraction of smaller crystals (20–50 nm in diameter), which are in good correlation with the calculated coherent scattering domain sizes of 19–87 nm based on X-ray data. The drug-polymer composites produced by nano spray drying process were identified as crystalline-amorphous nanostructured micronized solid dispersions.     

ReFlO: an interactive tool for pipe-and-filter domain specification and program generation

ReFlO is a framework and interactive tool to record and systematize domain knowledge used by experts to derive complex pipe-and-filter (PnF) applications. Domain knowledge is encoded as transformations that alter PnF graphs by refinement (adding more details), flattening (removing modular boundaries), and optimization (substituting inefficient PnF graphs with more efficient ones). All three kinds of transformations arise in reverse-engineering legacy PnF applications. We present the conceptual foundation and tool capabilities of ReFlO, illustrate how parallel PnF applications are designed and generated, and how domain-specific libraries of transformations are developed.     

Teaching model-driven engineering from a relational database perspective

We reinterpret MDE from the viewpoint of relational databases to provide an alternative way to understand, demonstrate, and teach MDE using concepts and technologies that should be familiar to undergraduates. We use (1) relational database schemas to express metamodels, (2) relational databases to express models, (3) Prolog to express constraints and M2M transformations, (4) Java tools to implement M2T and T2M transformations, and (5) Java to execute transformations. Application case studies and a user study illuminate the viability and benefits of our approach.     

The content of proteic and nonproteic (free and protein-bound) tryptophan in quinoa and cereal flours

The content of proteic and nonproteic (free and protein-bound) tryptophan and of proteins in quinoa, wheat, rice, maize, barley, oat, rye, spelt, sorghum and millet flours was determined. Protein content and proteic tryptophan of quinoa were similar to that of wheat and spelt, but higher than in other cereals. Free tryptophan in quinoa flour showed values similar to those of wheat, oat and sorghum Kalblank, lower than those of barley, spelt and pearl millet, but higher than in rice, maize, rye, sorghum DK 34 – Alabama hybrid. In addition, nonproteic tryptophan appears bound both to water soluble proteins and to proteins soluble at pH 8.9. The results are discussed regarding the importance of the nonprotein tryptophan fraction, the only one able to enter the brain, that is more easily absorbed, so guarantees a greater amount available for uptake by the central nervous system.     

Investigation of anti-corrosion properties of Ti:C gradient layers manufactured in hybrid deposition system

Excellent properties of hard carbon layers and especially, the unique combination of tribological, chemical and physical properties make them a popular coating material for use on surgical prosthesis, biomedical implants, and machine tools. However, their well-known poor adhesion and high internal stress disqualifies them in many possibilities of industrial applications. These drawbacks were improved by deposition of Ti buffer layer. By a combination of Radio Frequency Plasma Assisted Chemical Vapor Deposition (RFPACVD) and DC magnetron sputtering methods, thick carbon films were manufactured on Rex 734 steel. Structure and chemical composition of deposited layers was determined by scanning electron microscope and energy dispersive spectrometer analysis. The main purpose of this work was to determine the corrosion properties of Rex 734 alloy in a typical 0.5 M NaCl solution and to find the influence of Ti:C gradient layers on these properties. Anti-corrosion behavior was measured by the detection of corrosion potential in open circuit and the registration of potentiodynamic characteristics according to Stern–Geary and Tafel methods. Five different types of samples were studied: for full analysis the investigation was conducted for every structural component of the layer: for pure Ti deposited on Rex 734 as well as for Ti containing carbon layer and carbon layer deposited subsequently, and finally the corrosion resistance of Rex 734 steel was measured for comparison. As a result of the investigation it was noticed that the Ti–C interlayer enables to maximize the thickness of DLC films and Ti:C gradient layers have the good influence on the corrosion features of Rex 734 alloy. International Conference on Surfaces Coatings and Nanostructured Materials NanoSMat 2007 Organized by Society of Nanoscience and Nanotechnology.     

The effects of intrinsic and extrinsic acids on nanofilled and bulk fill resin composites: Roughness,surface hardness,and scanning electron microscopy analysis

The objective of this study was to examine the effects of extrinsic or intrinsic acids on nanofilled and bulk fill resin materials in vitro. A total of 90 disks were prepared using dental restorative material (Filtek Z350XT, GrandioSO, Filtek Bulk Fill, X‐tra fil). Thirty disks of each material were sub‐divided into three groups (n = 10) that were immersed for 7 days in deionized water (DW), 5% citric acid (CA—pH 2.1), or 0.1% hydrochloric acid (HCl—pH = 1.2). Surface hardness and roughness (stylus profilometer by R_a parameter) analysis were performed before and after immersion. Morphological changes were evaluated by scanning electron microscopy. The data were analyzed by two‐way ANOVA and Tukey's test (α = 0.05). All tested materials did not show significant differences in the effects of the DW, CA, or HCl solutions on surface roughness (p = .368). Likewise, the hardness loss was not affected by the solutions tested (p = .646), but there was a difference in the resin type (p = .002). Filtek Bulk Fill resin hardness was less affected, while Filtek Z350XT and GrandioSO presented the most hardness loss after 7 days of solution immersion. In terms of this experimental study, the results demonstrate the effectiveness of the mechanical properties (roughness and hardness surface) of nanofilled and bulk fill resin materials to resist erosion from extrinsic and intrinsic acids, therefore being potential candidates for dental applications.     

A single-chamber microbial fuel cell as a biosensor for wastewaters

The traditional 5-day test of the biochemical oxygen demand (BOD₅ test) has many disadvantages, and principally it is unsuitable for process control and real-time monitoring. As an alternative, a single-chamber microbial fuel cell (SCMFC) with an air cathode was tested as a biosensor and the performance analysed in terms of its measurement range, its response time, its reproducibility and its operational stability. When artificial wastewater was used as fuel, the biosensor output had a linear relationship with the BOD concentration up to 350 mg BOD cm⁻³; very high reproducibility; and stability over 7 months of operation.The system was further improved by reducing by 75% the total anolyte volume. In this way a response time close to the hydraulic retention time (HRT) of the biosensor (i.e. 40 min) was reached. When the small volume SCMFC biosensor was fed with real wastewater a good correlation between COD concentration and current output was obtained, demonstrating the applicability of this system to real effluents. The measurements obtained with the biosensor were also in accordance with values obtained with standard measurement methods.     

Effect of Heating Rate on Phase and Microstructural Evolution During Pressureless Sintering of a Nanostructured Transition Alumina

Deagglomeration of a nanocrystalline transition alumina performed using different techniques was first demonstrated to be active in the achievement of a better powder compaction ability under uniaxial pressing and consequently in the development of a highly dense and homogeneous microstructure during pressureless sintering. A major effect, however, was associated to the heating rate chosen during the densification cycle. In fact, the influence of different heating rates (10°C/min or 1°C/min) on phase and microstructural evolution during sintering was investigated in depth on the above best green bodies. A low-rate thermal cycle leads to a significant reduction of the α-Al₂O₃ crystallization temperature and promotes a more effective particle rearrangement during phase transformation. As a consequence, in the low-rate treated material, it was possible to avoid the development of a vermicular structure as usually expected during the densification of a transition alumina and to yield a more homogenously fired microstructure.