The release rate and antimicrobial activity of calcium-alginate films containing self-microemulsifying Thymus vulgaris essential oil against Escherichia coli and Staphylococcus aureus

The aim of this study was to fabricate antimicrobial calcium-alginate-based films containing the self-microemulsifying thyme essential oil (TEO) formulations using Tween 80 as the surfactant, and acetic (AA) or propionic (PA) acids as the cosurfactants. A Ca-alginate film containing nano-emulsified TEO as well as a neat Ca-alginate film were considered as the controls. The scanning electron microscopy micrographs showed a highly porous texture for SME films, which resulted in an increase in water vapor permeability and water absorption capacity of these films. The SME films released the TEO completely within 155 min and inhibited the growth of S. aureus and E. coli in in vitro antimicrobial tests. The population of S. aureus and E. coli reduced significantly in ground beef covered with SME films. The results of this study showed that self-microemulsifying TEO films could effectively increase the shelf life of ground beef by controlling its microbial population.     

Feature Selection for Recognition of Online Handwritten Bangla Characters

Feature selection through optimization techniques provides an interesting approach to minimize computational time with enhanced prediction capability, and     

Hydrogen production by silica membrane reactor during dehydrogenation of methylcyclohexane: CFD analysis

A comprehensive computational fluid dynamic model has been developed using COMSOL Multiphysics 5.4 software to predict the behavior of a membrane reactor in dehydrogenation of methylcyclohexane for hydrogen production. A reliable reaction kinetic of dehydrogenation reaction and a permeation mechanism of hydrogen through silica membrane have been used in computational fluid dynamic modeling. For performance comparison, an equivalent traditional fixed bed reactor without hydrogen removal has been also modeled. After model validation, it has been used to evaluate the operating parameters effect on the performance of both the silica membrane reactor and the equivalent traditional reactor as well. The operating temperature ranged between 473 and 553 K, pressure between 1 and 2.5 bar, sweep factor from ?6.22 to 25 and feed flow rate from 1 to 5 × 10^?6 mol/s. The membrane reactor performed better than the equivalent traditional reactor, achieving as best result complete methylcyclohexane conversion and 96% hydrogen recovery.     

Identifying the time of step change in binary profiles

Control charts are intended to aid quality practitioners in monitoring whether a change has occurred in a process. When a control chart indicates an out-of-control signal, it means that the process has changed. However, control chart signals do not indicate the real time of process changes; so estimators are applied to indicate the time when a change in the process takes place, which is referred to as the change point. This paper provides a maximum likelihood estimator to identify the real time of a step change in phase II monitoring of binary profiles, in which the quality of a process is characterized by a logistic regression between the response and predictor variables. Simulation studies are provided to evaluate the effectiveness of the change point estimator.     

Delayed self-regulation and time-dependent chemical drive leads to novel states in epigenetic landscapes

The epigenetic pathway of a cell as it differentiates from a stem cell state to a mature lineage-committed one has been historically understood in terms of Waddington''s landscape, consisting of hills and valleys. The smooth top and valley-strewn bottom of the hill represent their undifferentiated and differentiated states, respectively. Although mathematical ideas rooted in nonlinear dynamics and bifurcation theory have been used to quantify this picture, the importance of time delays arising from multistep chemical reactions or cellular shape transformations have been ignored so far. We argue that this feature is crucial in understanding cell differentiation and explore the role of time delay in a model of a single-gene regulatory circuit. We show that the interplay of time-dependent drive and delay introduces a new regime where the system shows sustained oscillations between the two admissible steady states. We interpret these results in the light of recent perplexing experiments on inducing the pluripotent state in mouse somatic cells. We also comment on how such an oscillatory state can provide a framework for understanding more general feedback circuits in cell development.     

Availability and cost-centered preventive maintenance scheduling of continuous operating series systems using multi-objective genetic algorithm: A case study

This article presents a multi-objective (maximization of availability and minimization of maintenance cost) preventive maintenance (PM) scheduling model for a continuous operating series system (COSS) which do not provide an off-working period for PM. The objective functions are optimized by using a Multi-Objective Genetic Algorithm (MOGA). The effectiveness of the model is demonstrated through a coal-fired boiler-tube. The case study shows that the model can improve the availability along with profound reduction of the maintenance cost, i.e., increases the profit of the plant.     

Sensitivity analysis of surface topography using the submerged non uniform piezoelectric micro cantilever in liquid by considering interatomic force interaction

Journal of Mechanical Science and Technology - The aim of this study is modeling and investigating the micro-cantilever (MC) vibration behavior of atomic force microscopy (AFM) more accurately by...     

An integrated virtual environment for feasibility studies and implementation of aerial MonoSLAM

This work presents a complete framework of an integrated aerial virtual environment (IAVE), which could effectively help implementing MonoSLAM (single-camera simultaneous localization and mapping) on an aerial vehicle. The developed system allows investigating different flight conditions without using any preloaded maps or predefined features. A 3D graphical engine integrated with a full 6 DOF aircraft dynamic simulator together with its trajectory generator completes the package. The 3D engine generates and accumulates real-time images of a general camera installed on the aerial vehicle. We effectively exploit C++ to develop the 3D graphics engine (3DGE) and all its associated visual effects, including different types of lighting, climate conditions, and moving objects. The existing 3DGE exploits the so-called Frenet Adapted Frames (FAF) with constrained angular velocities that is very effective in motion modeling of both ground and aerial moving objects. An in-house-developed MATLAB GUI puts into service the offline MonoSLAM system, which is very user friendly. The current version of IAVE effectively employs the so-called Inverse Depth Parameterization notions for features?? depth estimation in monocular SLAM, where different case studies show its dependable results for low-cost aerial navigation of a general aviation low-speed aircraft.