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151.
Remote‐controlled drug depots represent a highly valuable tool for the timely controlled administration of pharmaceuticals in a patient compliant manner. Here, the first pharmacologically controlled material that allows for the scheduled induction of a medical response in mice is described. To this aim, a novel, humanized biohybrid material that releases its cargo in response to a small‐molecule stimulus licensed for human use is developed. The functionality of the material in mice is demonstrated by the remote‐controlled delivery of a vaccine against the oncogenic human papillomavirus type 16. It is shown that the biohybrid depot‐mediated immunoprotection is equivalent to the classical multi‐injection‐based vaccination. These results indicate that this material can be used as a universal remote‐controlled vehicle for the patient‐compliant delivery of vaccines and pharmaceuticals.  相似文献   
152.
The great flexibility of the Beta function and its universal approximation characteristics, make Beta basis function neural networks (BBFNNs) very useful. We present a hardware implementation of the Beta neuron. The proposed circuit was designed by using a standard bipolar technology. PSPICE simulations show the good concordance of the output of our circuit with the analytic Beta function. We also successfully integrated the electronic Beta neuron in the design of a BBFNN that approximates a nonlinear mapping.  相似文献   
153.
Wireless Personal Communications - The cell-Free massive multiple input multiple output “mMIMO” networks can provide a satisfied performance for the fifth generation “5G”...  相似文献   
154.
As a network-based localized mobility management protocol, Proxy Mobile IPv6 (PMIPv6) enables a Mobile Host (MH) to roam within a localized domain without MH intervention in the mobility-related signalling. However, the PMIPv6 maintains MH mobility support in a restriction domain. Therefore, whenever the MH roams away from the PMIPv6 domain, its reachability status will be broken-down causing high handover latency and inevitable traffic loss for its communication session. This article proposes a proactive mechanism to mange the MH handover and maintain its data session continually across inter-PMIPv6-domains. The proposed mechanism introduces an intermediate global mobility anchor entity, called, which is responsible to coordinate MH handover as well as redirect its traffic across inter-PMIPv6-domains. Through various simulation evaluations, via ns-2, several experiments were conducted, revealing numerous results that verify the proposed mechanism superior performance over the conventional inter-PMIPv6-domain handover schemes in terms of handover latency, achieved throughput, protocol signalling cost and end-to-end traffic delivery latency.  相似文献   
155.
International Journal of Wireless Information Networks - Wireless access networks need to deliver a satisfactory level of Quality of Service (QoS) to their subscribers. The service quality can be...  相似文献   
156.
Opportunistic networking enables users to communicate in an environment where connectivity is intermittent or unstable. However, such networking scheme assumes that mobile nodes voluntary cooperate, which cannot be guaranteed. Some nodes can simply exhibit selfish behavior and thus diminish the effectiveness of the approach. In this paper, a game scenario is formulated in which the nodes try to convince each other to participate in packets forwarding. Each node is considered as a player in this game. When a node comes in the communication range of another, a bargaining game starts between them as part of the message forwarding process. Both players try to have a mutual agreement on a price for message forwarding. We present a new incentive mechanism called evolutionary bargaining‐based incentive scheme (EBIS) to motivate selfish nodes to cooperate in data forwarding. In EBIS, a node negotiates with other nodes to obtain an agreeable amount of credit for its forwarding service. Nodes apply a sequential bargaining game and then adapt their strategies using an evolutionary model to maximize the probability of reaching an agreement. Unlike classical bargaining games, nodes in our model are boundedly rational. In addition, we use the evolutionary stable strategy (ESS) concept to determine the adaptive strategies for the nodes. The comparison of EBIS with a benchmarked model demonstrates that EBIS performs better in terms of packet delivery ratio and average latency.  相似文献   
157.
ABSTRACT

With the aggressive scaling of integrated circuit technology, parametric estimation is a critical task for designers who looked for solutions to the challenges of some Nanoscale CMOS parameters. This paper presented the prediction of primary parameters of CMOS transistor for 16 nm to 10 nm process nodes using both of Bisquare Weights (BW) method and a novel recursive least squares (RLS) parameter estimation algorithm. The proposed RLS algorithm consists of the minimisation of a quadratic criterion relating to the prediction error in order to attain the best estimated parameters of the developed mathematical model. The obtained results thanks to the proposed RLS algorithm were better than those reached using the BW method. Comparisons between Predictive Technology Model (PTM) data and parameters estimated with RLS algorithm were made to check the validity and the consistency of the proposed algorithm. These predicted primary parameters were helpful to estimate and to optimise the performances of the Variable Gain Amplifier (VGA) which was a basic circuit element with a key role in the design of new upcoming receivers.  相似文献   
158.
Recently, Multi-sink Wireless Sensor Networks (WSNs) have received more and more attention due to their significant advantages over the single sink WSNs such as improving network throughput, balancing energy consumption, and prolonging network lifetime. Object tracking is regarded as one of the key applications of WSNs due to its wide real-life applications such as wildlife animal monitoring and military area intrusion detection. However, many object tracking researches usually focus on how to track the location of objects accurately, while few researches focus on data reporting. In this work, we propose an efficient data reporting method for object tracking in multi-sink WSNs. Due to the limited energy resource of sensor nodes, it seems especially important to design an energy efficient data reporting algorithm for object tracking in WSNs. Moreover, the reliable data transmission is an essential aspect that should be considered when designing a WSN for object tracking application, where the loss of data packets will affect the accuracy of the tracking and location estimation of a mobile object. In addition, congestion in WSNs has negative impact on the performance, namely, decreased throughput, increased per-packet energy consumption and delay, thus congestion control is an important issue in WSNs. Consequentially, this paper aims to achieve both minimum energy consumption in reporting operation and balanced energy consumption among sensor nodes for WSN lifetime extension. Furthermore, data reliability is considered in our model where the sensed data can reach the sink node in a more reliable way. Finally, this paper presents a solution that sufficiently exerts the underloaded nodes to alleviate congestion and improve the overall throughput in WSNs. This work first formulates the problem as 0/1 Integer Linear Programming problem, and proposes a Reliable Energy Balance Traffic Aware greedy Algorithm in multi-sink WSNs (REBTAM) to solve the optimization problem. Through simulation, the performance of the proposed approach is evaluated and analyzed compared with the previous work which is related to our topic such as DTAR, NBPR, and MSDDGR protocols.  相似文献   
159.
Numerical simulation has been performed to improve the performance of Cu2ZnSnS4 (CZTS) solar cells by replacing CdS with Zn1–xSnxO buffer layer. The influences of thickness, donor concentration and defect density of buffer layers on the performance of CZTS solar cells were investigated. It has been found that Zn1–xSnxO buffer layer for Sn content of 0.20 is better for CZTS solar cell. A higher efficiency can be achieved with thinner buffer layer. The optimized solar cell demonstrated a maximum power conversion efficiency of 13%.  相似文献   
160.
The rapid growth of wireless network technology such as HSDPA and WiMAX, has lead to greater demand for access to Internet via mobile hosts. Supporting mobile connection with fast and smooth roaming across heterogeneous wireless technologies has been an important challenge over past years. In this paper, a novel multilayer scheme for QoS-aware intra-domain mobility management is proposed. The mobility support capability is embedded in key components for the domain access network, namely, the Paging Access Routers and the Mobility-support Anchor Servers (MASs). The MASs are organized in three layers; starting from the top layer Superior-MASs, Middle-MASs and Inferior-MASs, respectively. The proposed scheme identified mobility support functionality, includes intra-domain anchor specification, route optimization algorithm, intra/inter-anchor mobility support, paging and authentication management. Simulation results of the proposed scheme show fair performance especially in the presence of QoS sensitive services.  相似文献   
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