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991.
Shape representation plays a vital role in any shape optimization exercise. The ability to identify a shape with good functional properties is dependent on the underlying shape representation scheme, the morphing mechanism and the efficiency of the optimization algorithm. This article presents a novel and efficient methodology for morphing 3D shapes via smart repair of control points. The repaired sequence of control points are subsequently used to define the 3D object using a B-spline surface representation. The control points are evolved within the framework of a memetic algorithm for greater efficiency. While the authors have already proposed an approach for 2D shape matching, this article extends it further to deal with 3D shape matching problems. Three 3D examples and a real customized 3D earplug design have been used as examples to illustrate the performance of the proposed approach and the effectiveness of the repair scheme. Complete details of the problems are presented for future work in this direction.  相似文献   
992.
993.
Objective: The objective of this study was to fabricate double-walled poly(lactide-co-glycolide) (PLGA) microspheres to increase encapsulation efficiency and avoid rapid release of hydrophilic drugs such as meglumine antimoniate.

Methods: In this study, double-walled and one-layered microspheres of PLGA were prepared using the emulsion solvent evaporation technique to better control the release of a hydrophilic drug, meglumine antimoniate (Glucantime®), which is the first choice treatment of cutaneous leishmaniasis. The effect of hydrophobic coating on microspheres' size, morphology, encapsulation efficiency and drug release characteristics was evaluated. Furthermore, the presence of antimony in meglumine antimoniate made it possible to observe the drug distribution within the microspheres' cross section by means of energy dispersive X-ray spectroscopy.

Results: Drug distribution images confirmed accumulation of the drug within the inner core of double-walled microspheres. In addition, these microspheres encapsulated the drug more efficiently up to 87% and demonstrated reduced initial burst and prolonged release compared to one-layered microspheres. These superiorities make double-walled microspheres an optimum candidate for sustained delivery of hydrophilic drugs.

Conclusion: Double-walled microspheres provide some advantages over traditional microspheres overcoming most of their limitations. Double-walled microspheres were found to be more efficient than their corresponding one-layered microspheres in terms of encapsulation efficiencies and release characteristics.  相似文献   

994.
995.
Abstract

Free-space communication allows one to use spatial mode encoding, which is susceptible to the effects of diffraction and turbulence. Here, we discuss the optimum communication modes of a system while taking such effects into account. We construct a free-space communication system that encodes information onto the plane-wave (PW) modes of light. We study the performance of this system in the presence of atmospheric turbulence, and compare it with previous results for a system employing orbital-angular-momentum (OAM) encoding. We are able to show that the PW basis is the preferred basis set for communication through atmospheric turbulence for a system with a large Fresnel number product. This study has important implications for high-dimensional quantum key distribution systems.  相似文献   
996.
This research explores the correlation between the structural properties of supramolecular biocomposites and their mechanical strength. Hybrid biocomposites composed of surface-modified hydroxyapatite nano-particles and supramolecular polycaprolactone (SP PCL), were prepared at different compositions, and their mechanical, thermal and viscoelastic properties as well as biodegradability, biocompatibility and cytotoxicity were evaluated in vitro. The results were compared with those for SP PCL/naked hydroxyapatite nano-composites. We show that surface modification of hydroxyapatite nanoparticles resulted in outstanding improvement of tensile strength and modulus up to 3.6 and 2.2-fold, respectively. At above 10 wt% HAp and 20 wt% HApUPy, heterogeneous nano-composites with inferior mechanical properties were obtained. Based on rheological (in steady shear mode) and small/wide angle X-ray scattering measurements, unusual improved mechanical properties were ascribed to the formation of supramolecular clusters around nanoparticles. In-vitro degradation of the supramolecular nano-composites was also studied to investigate the overall product biodegradation as well as toxicity of the degradation product(s).  相似文献   
997.
This paper illustrates an analytical probabilistic study of concrete beams subjected to torsion that are strengthened with carbon fiber reinforced polymer (CFRP). Hii and Al-Mahaidi’s method is one of the best analytical models for evaluating the torsional capacity of CFRP strengthened reinforced concrete beams. The first-order reliability method is carried out to probabilistically assess the capacity of CFRP-strengthened beams. For this aim, the statistical characteristics of design variables and model errors have been considered, followed by the determination of the average reliability indexes of the strengthened beams. The effect of each design variable on the average reliability is also determined. The assessment shows that the Hii and Al-Mahaidi’s analytical model is unconservative. In order to correct the situation, a more relaxed set of resistance factors for use in a load and resistance factor design format are needed. These are then determined for two target reliability levels of $ \beta_{\text T} $  = 3.0 and $ \beta_{\text T} $  = 3.5. It is found that factors of 0.9200 and 0.8225 are needed for target reliability levels, $ \beta_{\text T} $  = 3.0 and $ \beta_{\text T} $  = 3.5, respectively. Values of 0.9 and 0.8 are suggested for use in real practice depending on the target reliability sought.  相似文献   
998.
Accurate short-term load forecasting (STLF) is one of the essential requirements for power systems. In this paper, two different seasonal artificial neural networks (ANNs) are designed and compared in terms of model complexity, robustness, and forecasting accuracy. Furthermore, the performance of ANN partitioning is evaluated. The first model is a daily forecasting model which is used for forecasting hourly load of the next day. The second model is composed of 24 sub-networks which are used for forecasting hourly load of the next day. In fact, the second model is partitioning of the first model. Time, temperature, and historical loads are taken as inputs for ANN models. The neural network models are based on feed-forward back propagation which are trained and tested using data from electricity market of Iran during 2003 to 2005. Results show a good correlation between actual data and ANN outcomes. Moreover, it is shown that the first designed model consisting of single ANN is more appropriate than the second model consisting of 24 distinct ANNs. Finally ANN results are compared to conventional regression models. It is observed that in most cases ANN models are superior to regression models in terms of mean absolute percentage error (MAPE).  相似文献   
999.
In this paper, a photonic crystal (PhC) two-channel drop filter based on two 2×2 & 2×3 ring resonators is proposed. This structure is made of Germanium rods in an air background at a two-dimensional (2D) square lattice. Refractive index is chosen in a way in which that device can be easily fabricated. The photonic crystal two-channel drop filter is composed using a horizontal waveguide and two ring resonators, which are placed symmetrically about the horizontal axis. These ring resonators operate as energy coupling and capture the electromagnetic energy propagated in bus waveguide at their resonance frequencies. The filter characteristics are calculated using 2D finite-difference time-domain (FDTD) and plane wave expansion (PWE) methods. We show a two-channel drop filter with two resonators, based on studied basic structures and achieving optimal modes for channel drop filters with one resonator. We have done this through choosing the proper radii for all rods of lattice, setting radii of coupling rods, lattice constant, and studying basic structures having different refractive indexes. Finally, we show 84 % and 100 % dropping efficiencies can be achieved at D and C ports in the communication window and 100 % in direct port. The size of this device is 14.56 μm (length)×11.96 μm (width). This small size makes it possible to use the device in multiplexer applications in future communication systems and in all-optical integrated circuits.  相似文献   
1000.
This study was done to determine the optimum process conditions for absorption of sulfur dioxide in a mixture of flue gases. Using a selective amine-based absorber; a high amount of SO2 was absorbed in the scrubbing process. The process was designed to reduce the amount of sulfur dioxide. The pilot plant was designed and set up in the Research Center of Petroleum University of Technology, containing absorption and desorption stages. This paper reports an investigation of the effect and optimization of parameters that improve the efficiency of the whole process. The experiments were conducted under varying levels of desorption temperature, pH of the absorber solution, concentration of SO2 inlet gas, and flow rate of the absorbing solution. Using Taguchi experimental design method, the optimum conditions were identified for the absorption process. An efficiency of more than 99 % could be obtained by varying the parameters in which all the released SO2 gas was absorbed from the inlet flue gas; an achievement that is much favorable for industrial purposes.  相似文献   
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