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Synthetic bone grafts have been developed to provide an alternative to autografts and allografts. Bonelike® is a patented synthetic osteoconductive bone graft that mimics the mineral composition of natural bone. In the present preliminary animal studies a user-friendly version of synthetic bone graft Bonelike® have been developed by using a resorbable matrix, Floseal®, as a vehicle and raloxifene hydrochloride as a therapeutic molecule, that is known to decrease osteoclast activity and therefore enhanced bone formation. From histological and scanning electron microscopy evaluations, the use of Bonelike® associated with Floseal® and raloxifene hydrochloride showed that new bone was rapidly apposed on implanted granules and also that the presence of the matrix and therapeutic molecule does not alter the proven highly osteoconductivity properties of Bonelike®. Therefore, this association may be one step-forward for the clinical applications of Bonelike® scaffolds since it is much more easy-to-handle when compared to granular materials.  相似文献   
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The influence of chloride-ion concentration on the pitting behaviour of steel in saturated Ca(OH)2 solution was studied using the D.C. polarization technique. Results seem to indicate a threshold chloride level for the on-set of severe pitting around 3000 ppm, the pitting potential Ep exhibits dramatic drop and large hysteresis loops develop. The results provide insight into the pitting performance of steel in concrete and highlight the poor repassivation of this metal/environment system.  相似文献   
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The changing clinical dynamics of prostate cancer have resulted in a broadening of the research focus of the Genitourinary (GU) Cancer Committee of the Southwest Oncology Group (SWOG). Beginning with an emphasis on hormone-refractory disease in its early years, SWOG prostate cancer trials now cover the entire spectrum of the disease: localized, locally advanced, metastatic and hormone-refractory disease. As the world's largest GU cancer research group, the GU committee of SWOG has pioneered studies in combined androgen therapy for metastatic disease, quality-of-life (QOL) assessments for patients with localized and advanced disease, adjuvant therapy models, and prostate cancer chemoprevention. The committee has also formed the GU Global Group, whose purpose is to convene the chairs of the GU committees of all the major national and international oncology cooperative groups. Meeting semiannually, this group discusses activities within their respective organizations, plans collaborative strategies and protocols, and establishes global strategy in prostate cancer clinical research. The future directions of national and international prostate cancer trials will build on this broad foundation of well-conceived, logically sequenced studies.  相似文献   
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For pt.I see ibid., vol.31, no.4, p.359-68 (1989). A generalized ambiguity function for nonsinusoidal coded waveforms that are represented as a train of properly weighted Gaussian pulses is derived and analyzed to study its properties. Computer plots of generalized ambiguity functions of different binary codes, e.g. Barker, complementary, and pseudorandom codes, are presented. The various computer plots show that the desired thumbtack ambiguity function is achievable by nonsinusoidal coded waveforms  相似文献   
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The Journal of Supercomputing - The Internet of Things is a rapidly evolving technology in which interconnected computing devices and sensors share data over the network to decipher different...  相似文献   
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Neural Computing and Applications - Hand pose tracking is essential in sign languages. An automatic recognition of performed hand signs facilitates a number of applications, especially for people...  相似文献   
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Neural Computing and Applications - This paper introduces the use of the one-dimensional convolutional neural network (1D-CNN) for end-to-end EEG decoding with application towards a BCI system with...  相似文献   
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Neural Computing and Applications - Preserving red-chili quality is of utmost importance in which the authorities demand quality techniques to detect, classify, and prevent it from impurities. For...  相似文献   
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