Rethinking organizational design for managing multiple projects

This paper aims at positioning organizational design as an important phenomenon in the field of project management with a high potential of contributing to organizational theory. While organizational design has been neglected by scholars of management and organizational theory, it has been of great interest to those from the project management field. This incongruence—comprising the focus of this study—calls for new insights on theorization in context. The paper provides a preliminary theoretical framework combining contingency theory, the historical approach and social theory to understand organizational design, both as a thing and as a process. It provides empirical evidence from three case studies in healthcare. Findings confirm the specificity of each design while at the same time adopting a similar temporal pattern. We take this opportunity to highlight the seminal work of Rodney Turner on project-based organization and design.

The three roles of a project portfolio management office: Their impact on portfolio management execution and success

Project portfolio management offices (PPMOs) are a subset of project management offices (PMOs) that handle collections of multiple single projects and programmes, i.e. portfolios. PPMOs are centralised organisational units that cater to the demands of various stakeholders by performing specialised tasks. They are initiated by their organisation's leadership in response to increasing management challenges originating from project portfolios. Although there has been considerable research on PMOs in general, not only a clear understanding of multi-project PMOs' activity patterns set in specific contexts like project portfolio management, but also both existence and mode of multi-project PMOs' contribution to successful performance are still lacking. By quantitatively analysing PPMOs in 278 portfolios, we identify three different activity patterns, which are interpreted as distinctive roles. We show a significant positive effect of PPMOs' coordinating and controlling roles on performance in terms of project portfolio management quality, which is a predictor of portfolio success.     

Effect of temperature and water availability during late maturation of the soybean seed on germ and cotyledon isoflavone content and composition

BACKGROUND: Isoflavone content in soybean seeds is strongly influenced by both environment and genotype. However, little is known about the effect of environment and genotype on isoflavones in germ versus cotyledons. To determine the effect of temperature and soil moisture status during soybean seed development on seed isoflavone concentration and composition, a set of two French and three US cultivars of similar maturity were grown in the greenhouse. At the R6 growth stage, plants were subjected to one of three night/day temperature regimes (13/23°, 18/28° or 23/33 °C) in either optimal or sub‐optimal soil water conditions. RESULTS: In cotyledons, a three‐ to six‐fold variation in total isoflavone content was observed between the high and low temperature treatments, whereas the germ contents had less than a two‐fold variation. Soil water supply had less effect than temperature on the isoflavone contents and compositions. In both seed parts, the isoflavone concentrations were highly dependent on the cultivar. CONCLUSION: These results show that isoflavone content and composition in cotyledon and germ are unrelated and it should be possible to independently manipulate these seed traits through plant breeding and crop management systems. Copyright © 2007 Society of Chemical Industry     

Hydrolysis of intralipid by pancreatic lipase and phospholipase A2-gel filtration studies

Intralipid was incubated with pancreatic lipase (EC 3.1.1.3) and/or phospholipase A₂ (EC 3.1.1.4) at two bile salts/phosphatidylcholine molar ratios and at two different triglyceride hydrolysis rates using various amounts of lipase. Incubations were studied by gel filtration. Results show: (i) During lipase action, three phases of lipids coexist: an emulsified phase, a micellar phase and an intermediate heavy phase sized between the two others. The equilibrium between each phase is dependent upon the bile salts concentration. (ii) Under these conditions, pancreatic lipase was at 60% bound to the emulsified phase, whereas pancreatic phospholipase A₂ was bound at 94% to the micellar phase.     

Predicting high-risk preterm birth using artificial neural networks.

A reengineered approach to the early prediction of preterm birth is presented as a complimentary technique to the current procedure of using costly and invasive clinical testing on high-risk maternal populations. Artificial neural networks (ANNs) are employed as a screening tool for preterm birth on a heterogeneous maternal population; risk estimations use obstetrical variables available to physicians before 23 weeks gestation. The objective was to assess if ANNs have a potential use in obstetrical outcome estimations in low-risk maternal populations. The back-propagation feedforward ANN was trained and tested on cases with eight input variables describing the patient's obstetrical history; the output variables were: 1) preterm birth; 2) high-risk preterm birth; and 3) a refined high-risk preterm birth outcome excluding all cases where resuscitation was delivered in the form of free flow oxygen. Artificial training sets were created to increase the distribution of the underrepresented class to 20%. Training on the refined high-risk preterm birth model increased the network's sensitivity to 54.8%, compared to just over 20% for the nonartificially distributed preterm birth model.     

Couples' accounts of the effects of individual psychotherapy.

Describes 3 couples' experiences of one of the partners having been in psychotherapy, recounted during interviews conducted with each spouse individually. The information provided by the couples indicates that individual psychotherapy can have both positive and negative effects on the client's spouse and marital relationship. The importance of marital quality, couple adaptability, and shared problem perception in the adjustment to therapeutic changes is highlighted. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Recall of picture books by 3-year-old children: Testing and repetition effects in joint reading activities.

Parents use a variety of didactic techniques when they read to their preschool children, but little is known about which techniques are useful for different aspects of book learning. In our study 72 3-year-old children were read two picture books in their homes. Joint reading activities allowed planned comparisons of the effects of rereading and testing for recall during the second presentation of a book. An additional between-subject variable was whether the researcher or the child pointed to items to be remembered; the different books served as a within-subject variable. The dependent measure was memories of book items when the child was asked to anticipate events from page to page. There was little evidence that these memories were strengthened by the child's pointing during reading, but testing for recall and rereading the book were found to be effective for teaching the content. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

DNA sequence analysis of a 17 kb fragment of yeast chromosome XI physically localizes the MRB1 gene and reveals eight new open reading frames,including a homologue of the KIN1/KIN2 and SNF1 protein kinases

We report in this paper the sequence of a part of chromosome XI of Saccharomyces cerevisiae. This 17 kbp nucleotide sequence represents the right half of cosmid pUKG151 and contains nine open reading frames, YKL453, 450, 449, 448, 445, 443, 442, 441 and the 5′ part of YKL440. YKL440 was previously identified as the MBR1 gene and plays a role in mitochondrial biogenesis. YKL443 is a homologue of the yeast serine-rich protein (SRP1), while YKL453 presents strong homologies with the KIN1/KIN2/SNF1 kinase family. It must be pointed out that the size of this gene is well above average for yeast.