Stimulus-response compatibility with pure and mixed mappings in a flight task environment.

The present study examined the stimulus-response compatibility (SRC) effect in a simulated flight environment. Experiments 1 and 2 tested the effect with pure and mixed mappings in flight tasks by using attitude displays with inside-out and outside-in formats, whereas Experiments 3 and 4 used a simplified display and tasks. The SRC effect was obtained with mixed mappings when responses were turns of a flight yoke (Experiments 1-3). In contrast, the SRC effect was absent with mixed mappings when they were buttonpresses (Experiment 4). Analyses of sequential effects suggest that the reduction in Experiments 1-3 can be attributed to reduction in the frequency of trials for which the congruent mapping repeats, but the elimination in Experiment 4 cannot be. Implications of the findings are discussed in the context of aviation cockpit design. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Photoelectrochemical properties of rhodamine-C18 sensitized p-CuSCN photoelectrochemical cell (PEC)

Surface states in p-type Cu^I thiocyanate (CuSCN) were detected from I−V characteristics, diffuse reflectance spectra, and photocurrent action spectra. The p-CuSCN films are sensitized by rhodamine with octadecyl-alkyl chain, and the sensitized photocurrent is observed with the visible light illumination. In spite of the surface states in p-CuSCN, the maximum photocurrent quantum efficiency (gf_max) at λ = 560 nm, in 1 × 10⁻⁴ M KI + I₂ solution, pH = 6, reached 8.6%, where the surface dye concentration of photocathode Cu/p-CuSCN/Dye was 1.1 × 10¹⁴ molecules cm⁻². Photocathodes were biased at −0.25 V versus AgCl/Ag to give a zero dark current. From the variation of φ values with the reduction potential of electron acceptors, the cathodic sensitization mechanism presented is further confirmed.     

Anti-Allergic Drug Suppressed Pancreatic Carcinogenesis via Down-Regulation of Cellular Proliferation

Pancreatic cancer is a fatal disease, and thus its chemoprevention is an important issue. Based on the recent report that patients with allergic diseases have a low risk for pancreatic cancer, we examined the potential chemopreventive effect of anti-allergic agents using a hamster pancreatic carcinogenesis model. Among the three anti-allergic drugs administered, montelukast showed a tendency to suppress the incidence of pancreatic cancer. Further animal study revealed a significantly decreased incidence of pancreatic cancer in the high-dose montelukast group compared with controls. The development of the pancreatic intraepithelial neoplasia lesions was also significantly suppressed. The Ki-67 labeling index was significantly lower in pancreatic carcinomas in the high-dose montelukast group than in controls. In vitro experiments revealed that montelukast suppressed proliferation of pancreatic cancer cells in a dose-dependent manner with decreased expression of phospho-ERK1/2. Montelukast induced G1 phase arrest. Conversely, leukotriene D₄ (LTD₄), an agonist of CYSLTR1, increased cellular proliferation of pancreatic cancer cells with an accumulation of phospho-ERK1/2. In our cohort, pancreatic ductal adenocarcinoma patients with high CYSLTR1 expression showed a significantly unfavorable clinical outcome compared with those with low expression. Our results indicate that montelukast exerts a chemopreventive effect on pancreatic cancer via the LTD₄–CYSLTR1 axis and has potential for treatment of pancreatic carcinogenesis.     

Dye-sensitized photocatalyst for effective water splitting catalyst

Abstract

Renewable hydrogen production is a sustainable method for the development of next-generation energy technologies. Utilising solar energy and photocatalysts to split water is an ideal method to produce hydrogen. In this review, the fundamental principles and recent progress of hydrogen production by artificial photosynthesis are reviewed, focusing on hydrogen production from photocatalytic water splitting using organic–inorganic composite-based photocatalysts.     

Output Power Smoothing and Hydrogen Production by Using Variable Speed Wind Generators

This paper presents a combination system of wind energy conversion and hydrogen production. Hydrogen is expected as an alternative energy source in the future, and this is the best way to produce it from renewable energy like wind energy. On the other hand, the output of a wind generator, in general, fluctuates greatly due to wind speed variations, and thus the output fluctuations can have a serious influence on the power system operation. In the proposed system, a variable speed wind generator is adopted, and an electrolyzer is installed in parallel with it for hydrogen production. Output power from the wind generator is smoothed and supplied to the power system as well as to the electrolyzer based on the cooperative control method. The performance of the proposed system is evaluated by simulation analyses, in which simulations are performed by using PSCAD/EMTDC.      

The grand partition function of dilute biregular solutions

It has been demonstrated that the grand partition function (GPF) of biregular solutions contains in one single equation such thermodynamic principles as Henry's law, Raoult's law, the Gibbs-Duhem relation, Raoultian activity coefficients and their finite power series, Wagner's rec-iprocity, Schenck-Frohberg-Steinmetz's interchange, Lupis-Elliott's additivity, Mori-Morooka's disparity, and Darken's quadratic formalism. The logarithm of the Raoultian activity coefficient of species i, In γ_i should not be expressed by the Taylor series expansion, lest its truncation infringe the Gibbs-Duhem equation. The GPF methodology establishes that In γ_i, is not a vector but a scalar point function, free from any path dependence. While Darken's quadratic formalism employs three parameters to describe a ternary solution, the present biregularity approximation offers an alternative using seven empirical parameters, in case better accuracy is needed. Formerly Visiting Professor, Tohoku University, Japan     

Creating and retargetting motion by the musculoskeletal human body model

Recently, optimization has been used in various ways to interpolate or retarget human body motions obtained by motion-capturing systems. However, in such cases, the inner structure of a human body has rarely been taken into account, and hence there have been difficulties in simulating physiological effects such as fatigue or injuries. In this paper, we propose a method to create/retarget human body motions using a musculoskeletal human body model. Using our method, it is possible to create dynamically and physiologically feasible motions. Since a muscle model based on Hill's model is included in our system, it is also possible to retarget the original motion by changing muscular parameters. For example, using the muscle fatigue model, a motion where a human body gradually gets tired can be simulated. By increasing the maximal force exertable by the muscles, or decreasing it to zero, training or displacement effects of muscles can also be simulated. Our method can be used for biomechanically correct inverse kinematics, interpolation of motions, and physiological retargetting of the human body motion.     

Selective Isopropylation of Isobutylbenzene over H-Mordenite in Supercritical CO2 Medium: Remarkable Enhancement in Catalytic Activity and Selectivity for 4-Isobutylcumene

Remarkable enhancement in the catalytic activity and selectivity for the formation of 4-isobutylcumene (4-IBC) was observed in the isopropylation of isobutylbenzene (IBB) over highly dealuminated H-mordenite in supercritical CO₂ (sc-CO₂) medium. Thermogravimetric analyses confirm that reduced coking of the catalysts in sc-CO₂ medium and stronger acid sites in dealuminated H-mordenite (MOR) are the key factors for superior activity and selectivity for 4-IBC.     

The alkylation of naphthalene over three-dimensional large pore zeolites: The influence of zeolite structure and alkylating agent on the selectivity for dialkylnaphthalenes

In order to elucidate how zeolite structure and alkylating agent play roles in the shape-selective catalysis, the alkylation, i.e., isopropylation, sec-butylation, and tert-butylation, of naphthalene (NP) was examined over three-dimensional twelve-membered (12-MR) zeolites, Y (FAU), Beta (BEA), and CIT-1 (CON), and compared to that of H-mordenite (MOR). The β,β-selectivities (for β,β-dialkylnapthalene (β,β-DAN)) and the 2,6-selctivities (for 2,6-dialkylnaphthalene (2,6-DAN)) among DAN isomers varied with the types of zeolites and alkylating agents. FAU, BEA, and CON gave only low selectivities for 2,6-diisopropylnaphthalene (2,6-DIPN) in the isopropylation, and predominant isomers were bulky and thermodynamically unstable ,β-DIPN (1,3-, 1,6-, and 1,7-DIPN) and ,-DIPN (1,4- and 1,5-DIPN) at lower temperatures, and the formation of the less bulky and thermodynamically stable β,β-DIPN (2,6- and 2,7-DIPN) increased with increasing the temperature: they have quite different features from the shape-selective catalysis over MOR. These results suggest that FAU, BEA, and CON are not shape-selective in the isopropylation, and that the isopropylation is principally controlled kinetically at lower temperatures, and thermodynamically at higher temperatures.

The β,β-selectivities over FAU, BEA, and CON increased with increasing the bulkiness of alkylating agents, and were almost 100% in the tert-butylation. On the other hand, the 2,6-selectivities over these zeolites were much lower than those over MOR at a typically moderate temperature, 250 °C. These results mean that FAU, BEA, and CON have the shape-selective nature to give the less bulky isomers, β,β-DAN, in the sec-butylation and tert-butylation by using bulkier alkylating agents, particularly 2-methyl-2-propene: they can differentiate β,β-DAN from their isomers at the transition states by the steric restriction of zeolite channels. However, the channels of these zeolites are too large for differentiating 2,6- and 2,7-DAN even with 2-methyl-2-propene.