Iron-Catalyzed C−C Bond Formation via Chelation-Assisted C−H Activation

This review provides a brief overview of iron-catalyzed C−C bond forming reactions via heteroatom-assisted C−H bond activation, which have been extensively developed in the last decade. Three major types of reactions are discussed, namely, (1) C−H activation/C−C coupling using organometallic reagents under oxidative conditions, (2) C−H activation/C−C coupling using organic electrophiles under redox-neutral conditions, and (3) C−H activation/C−C coupling using unsaturated hydrocarbons under redox-neutral or oxidative conditions.     

Measurement of carbon sputtering yield by N ion beam and lifetime dependence of resulting foils on thickness

Carbon stripper foils with a higher nitrogen content were made by ion beam sputtering with reactive nitrogen gas. Such foils seem to be very useful as strippers for high-intensity heavy ion accelerators. To know further characteristics of the lifetime of such carbon foils, we have measured the sputtering yield of the carbon source material at a sputtering voltage of 4–15 kV and the lifetime dependence of such foils on thickness. Lifetime measurement was performed with a 3.2 MeV Ne⁺ ion beam. The sputtering yield on average showed 0.75 atoms/ion at over 9 kV sputtering voltage. The lifetime of the foils noticeably depends on the foil thickness, and the thickness range as practical stripper foil is to be around 15 to 33 μg/cm². Two foils made at 13 kV showed extremely long lifetimes of 6800 and 6000 mC/cm² at maximum and the foils made above 10 kV lived longer than about 900 mC/cm², which correspond to about 270 and 40 times longer than commercially available best foils. We measured the thickness ratio of nitrogen to carbon in each foil made at the different sputtering voltages and at the different irradiation stages (mC/cm²) by RBS method. We also inspected the structure of a nitrided carbon foil by transmission electron microscopy.     

Lifetime improvement of slackened thin cluster carbon stripper foils by suppression of carbon buildup

We control the amount of carbon buildup on slackened thin cluster carbon stripper foils (less than 3.5 μg/cm²) by heating with a high-power infrared lamp during beam bombardment. Foil lifetime measurements were performed using 2.0±0.5 μA beams of 3.2 MeV Ne⁺ ions and quantified as the total charge/area before breakage. Lifetimes were obtained up to 1286 mC/cm² at maximum and 1139 mC/cm² on the average; these values are, respectively, approximately 51 times at maximum and 46 times on average greater than the best commercially available foils, when used unheated and unslackened.     

Development of a method to lower recontamination after chemical decontamination by depositing Pt nano particles: (I) Consideration of the suppression mechanism using a quantum dynamics calculation

The Pt coating (Pt-C) process has been developed to lower the recontamination by radioactive elements after chemical decontamination of piping surfaces. In this process, a layer of fine Pt nano particles is formed in an aqueous solution on the base metal of the piping following the chemical decontamination. In this study, we confirmed that the suppression effect by the Pt-C toward ⁶⁰Co deposition on type 316 stainless steel using a ⁶⁰Co deposition test under hydrogen water chemistry. Furthermore, we investigated the suppression mechanism of deposition of radioactive elements by a quantum molecular simulation. The deposition amounts of ⁶⁰Co which were incorporated in oxides after 1000 h with and without the Pt-C process were about 90 and 10.2 Bq/cm², respectively. The amount of ⁶⁰Co deposition with Pt-C is about 10% that of non-coated specimens. The ⁶⁰Co incorporation for the Pt-C specimen was suppressed by decreasing the formation of oxides. We considered this phenomenon using a quantum dynamics calculation and concluded that the Fe–O bonds in oxides were weakened by the effect of Pt and hydrogen radicals which were produced in the reaction between H₂ and Pt, and then oxides were dissolved into the water.     

Advanced Method for Measuring Proteinase A in Beer and Application to Brewing*

Proteinase A, excreted from yeast cells into beer during fermentation in the brewing process, has been shown to degrade foam-active proteins and to decrease foam stability. In order to improve the measurement of this enzyme in beer, a new fluorescent peptide, MOCAc-Ala-Pro-Ala-Lys-Phe-Phe-Arg-Leu-Lys (Dnp)-NH₂, was synthesised and applied to the accurate and rapid estimation of proteinase A in commercial beer and fermenting wort. This novel substrate is several hundred times more sensitive to proteinase A than other previously reported synthetic substrates or native protein substrates. The concentration of proteinase A in beer is closely related to foam stability and proteinase A activity was found to increase gradually during fermentation. The concentration of proteinase A excreted from yeast cells is also closely related to the vitality of pitching yeast cells. This new method was successfully applied to the evaluation of yeast vitality and the development of optimum yeast handling procedures.     

Observation of multiple stroke and multipoint discharges by means of UHF interference

Results of interferometric observations of cloud‐to‐ground flashes in Darwin (Australia) have been analyzed to investigate some features of the lightning phenomenon. Our study focused on comparison between multipoint and multiple negative cloud‐to‐ground flashes. The speed of leaders was estimated with submillisecond resolution for both multipoint and multiple strokes. Leaders preceding the first stroke in multiple‐stroke flashes progress in a stepped fashion, and their behavior exhibits the same features as leaders in multipoint flashes. The estimated average speed of the leaders is on the order of 10⁵ m/s, and the mean step length is found to be 96 m with a mean pause time of 73 μs. The running time of the leader found from results of these observations has a mean value of 89 μs. The duration of UHF radiation bursts generated by leaders propagating along previously formed channels ranges from 0.2 to 55.3 ms with a mean value of 7.5 ms. By contrast, the duration of UHF radiation in leaders preceding multipoint strokes ranges from 21.1 to 90.6 ms with a mean value of 47.5 ms. The time intervals between strokes that strike at the same point as the previous stroke range from 22.5 to 330.6 ms with a mean value of 75.1 ms, while intervals between strokes in multipoint flashes range from 55.6 to 633.7 ms with a mean value of 149.1 ms. All leaders preceding multipoint strokes start in the same region inside the cloud. © 2001 Scripta Technica, Electr Eng Jpn, 134(4): 62–69, 2001     

Insulation diagnosis method for generator winding by measuring microwaves associated with dielectric breakdown

Partial discharge (PD) within voids in a solid insulating system is a symptom and/or a direct cause of deterioration of a generator winding. It is reported that PD is a very short duration current and/or voltage pulse, about 1 to 5 ns. Generally PD emits an electromagnetic wave which is a broadband range signal (≈ gigahertz). Therefore, we developed a new system for detecting the electromagnetic wave, especially microwaves (gigahertz) associated with a material defect of the winding. From the point of view of preventing accidents of insulation breakdown, it is important to assess the condition of the winding. We applied our system to a dielectric breakdown test to learn the relation between the characteristics of the microwaves and the insulation condition of the winding. The dielectric breakdown test is believed to be useful for estimating the minimum breakdown voltage which is a criterion of the insulation condition of the winding. Experimental results showed that this system was able to assess the insulation condition by measuring the number of pulses and the amplitude of the microwaves per voltage cycle. © 2000 Scripta Technica, Electr Eng Jpn, 132(1): 38–45, 2000     

Synthesis and biodegradation of copolyesterether of copoly(succinic anhydride/ethylene oxide) with polyether

The thermal properties and biodegradability of block copolyesterethers based on copoly[succinic anhydride (SA)/ethylene oxide (EO)] (polymer composition range SA/EO 42/58–49/51 mol %), synthesized by ring-opening copolymerization and poly(ethylene glycol) (PEG) or poly(propylene glycol) (PPG), were studied. The block copolyesterethers synthesized from higher than 7000 molecular weight (M_n) or high SA content copoly(SA/EO), SA/EO = 48/52 or 49/51, and PEG showed melting points and fusion heats (ΔH) similar to those of the prepolymers without leading to a microphase-separation structure. Enzymatic degradability of the block copolyesterethers synthesized from biodegradable copoly(SA/EO) with a low SA content (SA/EO = 42/58 mol %) and PEG was significantly smaller compared to that of the chain-extended copoly(SA/EO) used as a prepolymer. On the other hand, the block copolymers synthesized by an equimolar amount of copoly(SA/EO) and PPG showed evidence of a microphase-separation structure. An increase in propylene glycol (PG) content interfered with the formation of a microphase-separation structure. However, the block copolyesterethers including nonbiodegradable copoly(SA/EO), with a high SA content (SA/EO = 49/51 mol %), and PPG were found to be enzymatically degradable. In the biodegradation testing with standard activated sludge, the block copolyesterethers were degraded by microorganisms in activated sludge. The relationship between polymer composition and the biodegradation rate by activated sludge shows a similar trend to that of enzymatic hydrolysis. © 1998 John Wiley & Sons, Inc. J Appl Polym Sci 68: 2095–2106, 1998     

High Resolution Structure of the Mature Capsid of Ralstonia solanacearum Bacteriophage ϕRSA1 by Cryo-Electron Microscopy

The ϕRSA1 bacteriophage has been isolated from Ralstonia solanacearum, a gram negative bacteria having a significant economic impact on many important crops. We solved the three-dimensional structure of the ϕRSA1 mature capsid to 3.9 Å resolution by cryo-electron microscopy. The capsid shell, that contains the 39 kbp of dsDNA genome, has an icosahedral symmetry characterized by an unusual triangulation number of T = 7, dextro. The ϕRSA1 capsid is composed solely of the polymerization of the major capsid protein, gp8, which exhibits the typical “Johnson” fold first characterized in E. coli bacteriophage HK97. As opposed to the latter, the ϕRSA1 mature capsid is not stabilized by covalent crosslinking between its subunits, nor by the addition of a decoration protein. We further describe the molecular interactions occurring between the subunits of the ϕRSA1 capsid and their relationships with the other known bacteriophages.