全文获取类型
收费全文 | 114篇 |
免费 | 14篇 |
专业分类
化学工业 | 58篇 |
金属工艺 | 1篇 |
建筑科学 | 3篇 |
轻工业 | 38篇 |
水利工程 | 1篇 |
石油天然气 | 1篇 |
无线电 | 2篇 |
一般工业技术 | 12篇 |
原子能技术 | 1篇 |
自动化技术 | 11篇 |
出版年
2023年 | 1篇 |
2022年 | 22篇 |
2021年 | 17篇 |
2020年 | 6篇 |
2019年 | 3篇 |
2018年 | 5篇 |
2017年 | 2篇 |
2016年 | 6篇 |
2015年 | 6篇 |
2014年 | 7篇 |
2013年 | 5篇 |
2012年 | 10篇 |
2011年 | 8篇 |
2010年 | 5篇 |
2009年 | 5篇 |
2008年 | 2篇 |
2006年 | 1篇 |
2005年 | 3篇 |
2004年 | 4篇 |
2003年 | 1篇 |
2002年 | 1篇 |
2000年 | 2篇 |
1995年 | 2篇 |
1992年 | 1篇 |
1990年 | 1篇 |
1986年 | 1篇 |
1979年 | 1篇 |
排序方式: 共有128条查询结果,搜索用时 15 毫秒
91.
92.
Sohee Jeong Phillip J. Milner Liwen F. Wan Yi‐Sheng Liu Julia Oktawiec Edmond W. Zaia Alexander C. Forse Noemi Leick Thomas Gennett Jinghua Guo David Prendergast Jeffrey R. Long Jeffrey J. Urban 《Advanced materials (Deerfield Beach, Fla.)》2019,31(44)
Leveraging molecular‐level controls to enhance CO2 capture in solid‐state materials has received tremendous attention in recent years. Here, a new class of hybrid nanomaterials constructed from intrinsically porous γ‐Mg(BH4)2 nanocrystals and reduced graphene oxide (MBHg) is described. These nanomaterials exhibit kinetically controlled, irreversible CO2 uptake profiles with high uptake capacities (>19.9 mmol g?1) at low partial pressures and temperatures between 40 and 100 °C. Systematic experiments and first‐principles calculations reveal the mechanism of reaction between CO2 and MBHg and unveil the role of chemically activated, metastable (BH3‐HCOO)? centers that display more thermodynamically favorable reaction and potentially faster reaction kinetics than the parent BH4? centers. Overall, it is demonstrated that size reduction to the nanoscale regime and the generation of reactive, metastable intermediates improve the CO2 uptake properties in metal borohydride nanomaterials. 相似文献
93.
Noemi Pavo Eslam Samaha Inna Sabdyusheva Rembert Pogge von Strandmann Stefanie Stahnke Christian A. Plass Katrin Zlabinger Dominika Lukovic Zoltan Jambrik Imre J. Pavo Jutta Bergler-Klein William A. Gray Gerald Maurer Mariann Gyöngyösi 《Journal of materials science. Materials in medicine》2016,27(8):131
Here we investigated how a coating of intravascular balloon with paclitaxel (drug-coated balloon; DCB, Freeway?) impacted porcine peripheral artery vascular function and remodeling. Domestic swine (n = 54) underwent percutaneous overstretch balloon dilation of femoral and iliac arteries, controlled by angiography and optical coherence tomography (OCT). Paclitaxel tissue uptake was measured at 1 h and 1, 3, and 9 days post-dilation. At these time-points and at 32 ± 2 days, vascular function of the dilated arteries was assessed using the organ chamber model. Neointimal growth and remodeling indices were determined using OCT and histology at 32 ± 2 days. Intima and media fibrosis were quantified by picrosirius red staining. Post-inflation femoral artery tissue drug levels were 460 ± 214, 136 ± 123, 14 ± 6, and 0.1 ± 0.1 ng/mg at 1 h and 1, 3, and 9 days, respectively. Compared to plain balloon, Freeway? resulted in a significantly smaller neointimal area (P < 0.05), less tunica intima (8.0 ± 5.4 vs 14.2 ± 4.7 %) and media fibrosis (15.6 ± 7.7 vs 24.5 ± 5.4 %), and less femoral artery constrictive remodeling (remodeling index: 1.08 ± 0.08 vs 0.94 ± 0.08). The DCB was associated with significantly increased vasoconstrictor tone and endothelium-dependent vasodilation impairment shortly after post-overstretch injury. Overall, DCB dilation of peripheral arteries resulted in high drug uptake into arterial tissue. Compared with the plain balloon, the DCB was associated with decreased vessel wall fibrosis after balloon overstretch injury, and reduced degrees of constrictive remodeling and neointimal hyperplasia. 相似文献
94.
Ondine Lucaciu Mihaela Hedesiu Olga Soritau Noemi Dirzu Liana Crisan 《Particulate Science and Technology》2018,36(8):981-988
The knowledge of how cells respond to different treatments in terms of their migration potential could improve bone regeneration and osseointegration of dental implants. The objective of this study was to elucidate the effects of various chemoattractants, bone morphogenetic protein-2 (BMP-2), low-level laser therapy (LLLT), and cone beam computed tomography (CBCT) on the migration of dental follicle stem cells (DFSCs). The chemoattractants used in our study were the serum-free (SF) conditioned media that were harvested from osteoblast cell cultures seeded on the surface of titanium implants—Ti6Al7Nb (TiCtrl), implants infiltrated with hydroxyapatite (TiHA), with silicatitanate (TiSiO2), and from culture of DFSCs cultivated on TiCtrl implants. We used the scratch migration assay to evaluate the influence of BMP-2, LLLT therapy, and CBCT on the migration potential of DFSCs. The migration scratch assay indicates that the BMP-2 growth factor is able to increase the DFSC migration compared to control culturing medium and regardless of laser or CBCT exposure. The results demonstrate the importance of improving the implant surface with HA, SiO2, and DFSCs. Stimulated DFSCs will secrete growth factors which will act as chemoattractants for the stem cells of the implant host. Adding growth factors such as BMP-2 can improve the migration process of DFSCs. 相似文献
95.
Maria Favia Andrea Gerbino Elisabetta Notario Vincenzo Tragni Maria Noemi Sgobba Maria Elena DellAquila Ciro Leonardo Pierri Lorenzo Guerra Elena Ciani 《International journal of molecular sciences》2022,23(3)
H+/K+ ATPase Type 2 is an heteromeric membrane protein involved in cation transmembrane transport and consists of two subunits: a specific α subunit (ATP12A) and a non-specific β subunit. The aim of this study was to demonstrate the presence and establish the localization of ATP12A in spermatozoa from Bubalus bubalis, Bos taurus and Ovis aries. Immunoblotting revealed, in all three species, a major band (100 kDa) corresponding to the expected molecular mass. The ATP12A immunolocalization pattern showed, consistently in the three species, a strong signal at the acrosome. These results, described here for the first time in spermatozoa, are consistent with those observed for the β1 subunit of Na+/K+ ATPase, suggesting that the latter may assemble with the α subunit to produce a functional ATP12A dimer in sperm cells. The above scenario appeared to be nicely supported by 3D comparative modeling and interaction energy calculations. The expression of ATP12A during different stages of bovine sperm maturation progressively increased, moving from epididymis to deferent ducts. Based on overall results, we hypothesize that ATP12A may play a role in acrosome reactions. Further studies will be required in order to address the functional role of this target protein in sperm physiology. 相似文献
96.
Effect of chlorine on filamentous microorganisms present in activated sludge as evaluated by respirometry and INT-dehydrogenase activity 总被引:2,自引:0,他引:2
Activated sludge technology is more used than any other for biological treatment of wastewater. However, filamentous bulking is a very common problem in activated sludge plants, chlorine being the chemical agent normally used to control it. In this work the effect of chlorine on microorganisms present in activated sludge flocs was assessed by a respirometric technique (oxygen uptake rate, OUR) and by the INT-dehydrogenase activity test (DHA) measured by two techniques: spectrophotometry (DHA(a)) and image analysis (DHA(i)). Both DHA tests were optimized and correlated with the respirometric technique (OUR) using pure cultures of a filamentous microorganism (Sphaerotilus natans) under chlorine inhibition. Using these correlations the tested methods were applied to determine the action of chlorine on respiratory activity in activated sludge. The OUR and the DHA(a) quantifies the action of chlorine on the total respiratory activity (RA) of flocs (filamentous and floc-forming bacteria); in contrast, the DHA(i) test evaluates specific action of chlorine on the RA of filamentous microorganisms. In activated sludge flocs containing filamentous microorganisms, a chlorine dose of 4.75 mgCl(2) (gVSS)(-1) with a contact time of 20 min reduced about 80% of the RA of filamentous bacteria while affecting only 50-60% of the total RA of flocs. Besides, a chlorine dose of 7.9 mgCl(2) (gVSS)(-1) produced the total respiratory inactivation of filamentous microorganisms after 10 min contact, however, with this dose the total RA of activated sludge flocs was reduced only about 45-65%; controlling filamentous bulking without affecting too much floc-forming bacteria. At the tested chlorine concentrations the inhibition of filamentous microorganisms was higher than in the whole activated sludge. Although floc-forming microorganisms were demonstrated to be more susceptible to chlorine than filamentous in pure cultures, results obtained in the present work confirmed that it is the location of the filamentous microorganisms in the flocs and the presence of extracellular polymer substances which largely determines their higher susceptibility to chlorine; consequently this feature plays a critical role in bulking control. 相似文献
97.
98.
Franciele M. PelissariMaría A. Garcia Miriam N. Martino Noemi E. Zaritzky Maria Victoria E. Grossmann 《Journal of food engineering》2012,108(2):262-267
Films composed of cassava starch, chitosan and glycerol were produced by blown extrusion and employing a design for constrained surfaces and mixtures. The effects of the components of the mixture on the mechanical properties, water vapor permeability (WVP) and opacity of the films were studied. According to the models generated by the design, the concentration of starch had a positive effect in all properties. The plasticizer glycerol and its interactions with other components had a positive effect on increasing the WVP. The presence of a higher relative concentration of chitosan favored the formation of more rigid and opaque and less permeable films. In general, the concentrations of starch, chitosan and glycerol led to changes in the film properties, potentially affecting their performance. The design for constrained surfaces and mixtures proved to be a useful tool for this type of study due to the complexity of the conditions of film formation. 相似文献
99.
Lorenzo JM Montes R Purriños L Cobas N Franco D 《Journal of the science of food and agriculture》2012,92(6):1311-1317
BACKGROUND: The influence of sex and location of fat in the carcass on the fatty acid profile of Celta pigs was studied. Twenty pigs (10 castrated males and 10 females) from the Carballina line were used. RESULTS: The fatty acids composition was predominated by monounsaturated fatty acids (MUFA; approximately 48% of total methyl esters), followed by saturated fatty acids (SFA; approximately 40% of total methyl esters) and, finally, polyunsaturated fatty acids (PUFA; approximately 12% of total methyl esters). The sex and location of fat in the carcass showed significant differences in PUFA and SFA content while both factors were not significantly different with respect to MUFA content. Linoleic, linolenic, eicosatrienoic and arachidonic fatty acids showed the largest difference among the three locations (intramuscular, subcutaneous ventral and subcutaneous dorsal) of the fat in the carcass. CONCLUSION: The fatty acid profile that we observed in the fat of the Celta pigs does not differ greatly from those described by other authors in other autochthonous pig breeds. Principal component analysis offered a good separation of the mean samples according to the sex and location of fat of the pigs. Copyright © 2011 Society of Chemical Industry 相似文献
100.
Massimiliano Cuccioloni Valentina Cecarini Laura Bonfili Riccardo Pettinari Alessia Tombesi Noemi Pagliaricci Laura Petetta Mauro Angeletti Anna Maria Eleuteri 《International journal of molecular sciences》2022,23(15)
Alzheimer’s disease (AD) is a fatal neurodegenerative disorder associated with severe dementia, progressive cognitive decline, and irreversible memory loss. Although its etiopathogenesis is still unclear, the aggregation of amyloid-β (Aβ) peptides into supramolecular structures and their accumulation in the central nervous system play a critical role in the onset and progression of the disease. On such a premise, the inhibition of the early stages of Aβ aggregation is a potential prevention strategy for the treatment of AD. Since several natural occurring compounds, as well as metal-based molecules, showed promising inhibitory activities toward Aβ aggregation, we herein characterized the interaction of an organoruthenium derivative of curcumin with Aβ(1–40) and Aβ(1–42) peptides, and we evaluated its ability to inhibit the oligomerization/fibrillogenesis processes by combining in silico and in vitro methods. In general, besides being less toxic to neuronal cells, the derivative preserved the amyloid binding ability of the parent compound in terms of equilibrium dissociation constants but (most notably) was more effective both in retarding the formation and limiting the size of amyloid aggregates by virtue of a higher hindering effect on the amyloid–amyloid elongation surface. Additionally, the complex protected neuronal cells from amyloid toxicity. 相似文献