Ultrastructural evidence for an innervation of epithelial enterochromaffine cells in the guinea pig duodenum

The innervation of the duodenal enterochromaffine cells (E.C.) of the guinea pig was studied at the electronmicroscopic level. Pretreatment with 5-OH-dopamine was performed to visualize catecholaminergic (CA) nervous elements. Near the basement membrane of all examined E.C. in the crypts, bundles of unmyelinated nerve processes were observed, only partly ensheathed in a Schwann cell cover. At least 4 types of processes could be observed. 1) Boutons containing only small clear vesicles, probably cholinergic fibres; 2) boutons with small clear vesicles, and in addition large (greater than 200 nm) granules with a dense matrix (P-type-fibres); 3) boutons with small electron-dense vesicles, probably CA-fibres; and 4) processes with few vesicles but having the appearance of dendrites. No typical synaptic arrangements were observed, but the minimal distance between the E.C. and the nerve bundles was 150 to 250 nm, thus well within the functional limits of the "autonomic gap". Thus epithelial E.C. may be influenced by several types of nervous elements, including CA-fibres.     

Exploring US Business Cycles with Bivariate Loops Using Penalized Spline Regression

The phrase business cycle is usually used for short term fluctuations in macroeconomic time series. In this paper we focus on the estimation of business cycles in a bivariate manner by fitting two series simultaneously. The underlying model is thereby nonparametric in that no functional form is prespecified but smoothness of the functions are assumed. The functions are then estimated using penalized spline estimation. The bivariate approach will allow to compare business cycles, check and compare phase lengths and visualize this in forms of loops in a bivariate way. Moreover, the focus is on separation of long and short phase fluctuation, where only the latter is the classical business cycle while the first is better known as Friedman or Goodwin cycle, respectively. Again, we use nonparametric models and fit the functional shape with penalized splines. For the separation of long and short phase components we employ an Akaike criterion.     

Cost efficiency comparison of four video-based techniques for assessing upper arm postures

Many video-based techniques for assessing postures at work have been developed. Choosing the most appropriate technique should be based on an evaluation of different alternatives in terms of their ability to produce posture information at low input costs, i.e. their cost efficiency. This study compared four video-based techniques for assessing upper arm postures, using cost and error data from an investigation on hairdressers. Labour costs associated with the posture assessments from the video recordings were the dominant factor in the cost efficiency comparison. Thus, a work sampling technique associated with relatively large errors appeared, in general, to be the most cost-efficient because it was labour-saving. Measurement bias and other costs than labour cost for posture assessment influenced the ranking and economic evaluation of techniques, as did the applied measurement strategy, i.e. the numbers of video recordings and repeated assessments of them. PRACTITIONER SUMMARY: The cost efficiency of four video-based techniques for assessing upper arm postures was compared. Work sampling techniques were in general more cost efficient than continuous observations since they were labour-saving. Whilst a labour cost dominated the comparison, 'hidden costs', bias and measurement strategy also influenced this dominance.     

The effect of flooring on musculoskeletal symptoms in the lower extremities and low back among female nursing assistants

This study examines the effect of changing the floor from a 2-mm homogenous vinyl floor to a 4-mm heterogeneous vinyl floor (1.5-mm wear layer and 2.5-mm foam layer) on musculoskeletal symptoms in the lower extremities and low back among nursing assistants in a geriatric care centre. A pre-post design with a reference group consisting of nursing assistants from a similar geriatric care centre was used. Follow-up measurements were carried out 12 and 24 months after the intervention by means of questionnaires. At the 1-year follow-up, the pain intensity score in the feet of the intervention group had decreased compared with the baseline value and remained statistically significant at the 2-year follow-up. The decrease in pain intensity score of the feet in the intervention group was statistically significantly different from the reference group, both after 1 and 2 years. PRACTITIONER SUMMARY: The results show the importance of flooring in the workplace with regard to reducing musculoskeletal symptoms. Appropriate flooring is especially important in the female-dominated health care sector, where workers must stand or walk for long periods.     

Composite indicator for railway infrastructure management

Railway Engineering Science - The assessment and analysis of railway infrastructure capacity is an essential task in railway infrastructure management carried out to meet the required quality and...     

Analysing quadratic effects of formative constructs by means of variance-based structural equation modelling

Together with the development of information systems research, there has also been increased interest in non-linear relationships between focal constructs. This article presents six Partial Least Squares-based approaches for estimating formative constructs’ quadratic effects. In addition, these approaches’ performance is tested by means of a complex Monte Carlo experiment. The experiment reveals significant and substantial differences between the approaches. In general, the performance of the hybrid approach as suggested by Wold (1982) is most convincing in terms of point estimate accuracy, statistical power, and prediction accuracy. The two-stage approach suggested by Chin et al (1996) showed almost the same performance; differences between it and the hybrid approach – although statistically significant – were unsubstantial. Based on these results, the article provides guidelines for the analysis of non-linear effects by means of variance-based structural equation modelling.     

Plastic deformation of linear polyethylene containing row structures

The mechanical and thermal properties of highly oriented polyethylene films containing shish kebab type morphology are studied. At low deformations (strain<10%) strong work hardening is observed. Higher deformations ((40%) give rise to strain softening of the material and a decrease in the Young's modulus of as much as one-third of its initial value. In addition, the high melting component of the material originating from the shish-type crystals vanishes on higher deformation. The deformation processes are discussed from the point of view of a fibre-composite material and structural changes during the deformation are followed by transmission electron microscopy.     

On the prediction of band-limited signals from past samples

A new method is used to construct coefficients a_kn such that any band-limited signal function with highest frequency ΠW can be reconstituted from its samples from the past via

$\text{?(t)=}\text{lim}\text{n→∞}\text{σ}\text{k=1}\text{n}\text{a}{}_{\mathrm{kn}}\text{?}\text{t?}\text{kT}\text{W}$

Although the existence of such predictor coefficients can be proved for each positive T < 1, so far they have been exhibited only for $\text{T ? (0,}\text{built1}\text{2}\text{)}$ by J. L. Brown, Jr. [1]. Using the mathematical tool of power series expansions in the complex domain, T can be extended to at least $\text{T <}\text{1}\text{2}$, that is, the sampling rate has to exceed three-halves the Nyquist rate. Again the predictor coefficients a_kn do not depend on the structure of ? or on the bandwidth parameter W.