Impedance as a method to sense proximity at the electrode-retina interface

Precise positioning of a stimulating electrode in the eye is not possible by simple visualization. However, reliable measurement of responses to retinal stimulation requires consistent positioning. The present study focuses on impedance measurement techniques to sense the proximity of the electrode to the retina. A platinum-iridium stimulation electrode was placed inside the rat eye and impedance was recorded at different positions of the stimulating electrode relative to the retina. The presence of robust electrically evoked response in the superior colliculus indicates that the electrode may not have to be in absolute contact in order to elicit a neural response. Optical coherence tomography imaging confirmed the distance-impedance relationship.     

Evaluation of an energy-based fatigue approach considering mean stress effects

In this paper, an attempt is made to extend the total strain energy approach for predicting the fatigue life subjected to mean stress under uniaxial state. The effects of means stress on the fatigue failure of a ferritic stainless steel and high pressure tube steel are studied under strain-controlled low cycle fatigue condition. Based on the fatigue results from different strain ratios, modified total strain energy density approach is proposed to account for the mean stress effects. The proposed damage parameter provides convenient means of evaluating fatigue life with mean stress effects considering the fact that the definitions used for measuring strain energies are the same as in the fully-reversed cycling (R = ?1). A good agreement is observed between experimental life and predicted life using proposed approach. Two other mean stress models (Smith-Watson-Topper model and Morrow model) are also used to evaluate the low cycle fatigue data. Based on a simple statistical estimator, the proposed approach is compared with these models and is found realistic.     

The dependence of spectral impedance on disc microelectrode radius

As microelectrodes gain widespread use for electrochemical sensing, biopotential recording, and neural stimulation, it becomes important to understand the dependence of electrochemical impedance on microelectrode size. It has been shown mathematically that a disc electrode, coplanar in an insulating substrate and exposed to a conducting media, exhibits an inhomogeneous current distribution when a potential step is applied. This distribution is known as the primary distribution, and its derivation also yielded an analytic solution for electrical resistance of the conducting media (R(s)), between the disc surface and a distant ground, which is inversely proportional to disk radius [R(s) = 1/(4kappar), where kappa is media conductivity and r is disk radius]. The dependence of spectral impedance on microelectrode radius, however, has not been explored. We verify the analytical solution for resistance using high-frequency (100 kHz) electrochemical impedance data from microelectrodes of varying radius (11-325 microm). For all disc radii, as we approach a lower frequency (--> 10 Hz), we observe a transition from radial to area dependence (e.g., 1/r --> 1/r2). We hypothesize that this transition is driven by the fact that the derivation of the primary distribution ignores concentration gradients, but that these gradients cannot be ignored at lower frequencies.     

Electrical stimulation in isolated rabbit retina.

Experiments were conducted to assess the effect of stimulating electrode parameters (size, position, and waveform shape) on electrically elicited ganglion cell action potentials from isolated rabbit retina. Thirty-eight isolated rabbit retinas were stimulated with bipolar stimulating electrodes (either 125 or 25 microm in diameter) positioned on either the ganglion or the photoreceptor side. Recording electrodes were placed between the optic disc and the stimulating electrodes. Cathodic-first, biphasic, current waveforms of varying pulse durations (0.1, 0.5, 1 ms) were used. For the four conditions tested (125-electrode and 25-microm electrode, ganglion cell, and photoreceptor positions) threshold currents ranged from 6.7 to 23.6 microA, depending on location and pulse duration. With 1-ms pulse duration, no statistically significant difference was seen between threshold currents when either size electrode was used to stimulate either the ganglion cell side or the photoreceptor side. For all groups, the threshold currents using the 1-ms pulse were lower than those using 0.1 ms, but the 0.1-ms pulses used less charge. These experiments provide a number of valuable insights into the relative effects of several stimulation parameters critical to the development of an implanted electronic retinal prosthesis.     

Video-Based Automatic Incident Detection for Smart Roads: The Outdoor Environmental Challenges Regarding False Alarms

Video-based automatic incident detection (AID) systems are increasingly being used in intelligent transportation systems (ITS). Video-based AID is a promising method of incident detection. However, the accuracy of video-based AID is heavily affected by environmental factors such as shadows, snow, rain, and glare. This paper presents a review of the different work done in the literature to detect outdoor environmental factors, namely, static shadows, snow, rain, and glare. Once these environmental conditions are detected, they can be compensated for, and hence, the accuracy of alarms detected by video-based AID systems will be enhanced. Based on the presented review, this paper will highlight potential research directions to address gaps that currently exist in detecting outdoor environmental conditions. This will lead to an overall enhancement in the reliability of video-based AID systems and, hence, pave the road for more usage of these systems in the future. Last, this paper suggests new contributions in the form of new suggested algorithmic ideas to detect environmental factors that affect AID systems accuracy.     

Simulation of Solid Tubular Expansion in Well Drilling Using Finite Element Method

Solid expandable tubular is an emerging and promising technology in petroleum industry. It consists of increasing the diameter of a tubular by hydraulically pushing or mechanically pulling a conical mandrel through it. In this paper, a dy namic explicit finite element analysis (FEA) has been used to study the solid tubular expansion using ABAQUS, a commercial FEA software package. The required drawing force for tubular expansion was estimated for different mandrel shapes, friction coefficients, and expansion ratios. The drawing force increases with the increase in friction coefficient and expansion ratio. It was also found that the material velocities increase on the front of the mandrel but decrease to zero in the post expansion section. Moreover, the plastic deformation shows a reduction of thickness with friction coefficient and expansion ratio. Simulation results also revealed that contact occurs at the two ends of the conical mandrel tubular interface and that the contact stress increases with friction coefficient reaches to maximum value at an expansion ratio of 20%.     

Effects of Boundary Conditions in Laminated Composite Plates Using Higher Order Shear Deformation Theory

This paper extends the applicability of a modified higher order shear deformation theory to accurately determine the in-plane and transverse shear stress distributions in an orthotropic laminated composite plate subjected to different boundary conditions. A simpler, two-dimensional, shear deformable, plate theory accompanied with an appropriate set of through-thickness variations, is used to accurately predict transverse shear stresses. A finite element code was developed based on a higher order shear deformation theory to study the effects of boundary conditions on the behavior of thin-to-thick anisotropic laminated composite plates. The code was verified against three dimensional elasticity results. The study also compared the stresses and deformation results of higher order theory with those obtained using commercial software such as LUSAS, ANSYS and ALGOR. The commercial software are heavily used by designers to design various components/products made of composites. Various combinations of fixed, clamped and simply supported boundary conditions were used to verify a large class of anticipated applications. Results obtained from software are in good agreement for some cases and significantly differ for others. It was found that LUSAS and ANSYS yield better results for transverse deflection and in-plane stresses. But for transverse shear stresses, it is highly dependent on boundary conditions.