Analyzing developmental processes on an individual level using nonstationary time series modeling.

Individuals change over time, often in complex ways. Generally, studies of change over time have combined individuals into groups for analysis, which is inappropriate in most, if not all, studies of development. The authors explain how to identify appropriate levels of analysis (individual vs. group) and demonstrate how to estimate changes in developmental processes over time using a multivariate nonstationary time series model. They apply this model to describe the changing relationships between a biological son and father and a stepson and stepfather at the individual level. The authors also explain how to use an extended Kalman filter with iteration and smoothing estimator to capture how dynamics change over time. Finally, they suggest further applications of the multivariate nonstationary time series model and detail the next steps in the development of statistical models used to analyze individual-level data. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Privacy from Promises to Protection

Privacy issues are becoming more and more important especially since the cyber and the real world are converging up to certain extent when using mobile devices. Means that really protect privacy are still missing. The problem is, as soon as a user provides data to a service provider the user looses control over her data. The simple solution is not to provide any data but then many useful services, e.g. navigation applications, cannot be used. In order to solve this problem, we propose privacy guaranteeing execution containers (PGEC). Basically the concept is that the application obtains access to the user data in a specially protected and certified environment, the PGEC. PGECs enable applications to access private user data and guarantee that the user data is deleted as soon as the service is quit. The PGEC also restricts the communication between the application and the service provider to what is explicitly allowed by the service user. In addition to those means the PGEC also implements countermeasures against malicious attacks such as modified host systems and covert channel attacks, which might be misusing CPU load to signal data out of the PGEC. Thus, the PGEC guarantees a “one time use” of the provided private data.     

Concurrent Q‐learning: Reinforcement learning for dynamic goals and environments

This article presents a powerful new algorithm for reinforcement learning in problems where the goals and also the environment may change. The algorithm is completely goal independent, allowing the mechanics of the environment to be learned independently of the task that is being undertaken. Conventional reinforcement learning techniques, such as Q‐learning, are goal dependent. When the goal or reward conditions change, previous learning interferes with the new task that is being learned, resulting in very poor performance. Previously, the Concurrent Q‐Learning algorithm was developed, based on Watkin's Q‐learning, which learns the relative proximity of all states simultaneously. This learning is completely independent of the reward experienced at those states and, through a simple action selection strategy, may be applied to any given reward structure. Here it is shown that the extra information obtained may be used to replace the eligibility traces of Watkin's Q‐learning, allowing many more value updates to be made at each time step. The new algorithm is compared to the previous version and also to DG‐learning in tasks involving changing goals and environments. The new algorithm is shown to perform significantly better than these alternatives, especially in situations involving novel obstructions. The algorithm adapts quickly and intelligently to changes in both the environment and reward structure, and does not suffer interference from training undertaken prior to those changes. © 2005 Wiley Periodicals, Inc. Int J Int Syst 20: 1037–1052, 2005.     

Correlation of film structure and molecular oxygen reduction at nitrogen doped amorphous carbon thin film electrochemical electrodes

Nitrogen doped amorphous carbon (a-C:N) thin film electrodes with a range of film structures have been deposited using a filtered cathodic vacuum arc system. The correlation between film structure and electro-reduction of molecular oxygen in aqueous media at the electrodes has been explored. In aqueous 0.1 M NaOH, dioxygen reduction is inhibited at all the a-C:N electrodes compared with that at glassy carbon electrodes. The potential of the dioxygen reduction current peak shifts negatively at a-C:N electrodes as the sp³ C fraction in the a-C:N materials increases, while the current peak height decreases simultaneously. The a-C:N electrodes possess high sensitivity for investigating the mechanism of dioxygen reduction. It was found that the catalytic H₂O₂ reduction to H₂O on carbon materials is attributed to oxygen species at sp² C sites.     

Noise Reduction Methods for Weighing Lysimeters

Mechanical vibration of the grass and crop weighing lysimeters, located at the University of California West Side Field Research and Extension Station at Five Points, Calif. generated noise in lysimeter mass measurements and reduced the quality of evapotranspiration (ET) data. The estimated power spectral density (PSD) for grass lysimeter mass data acquired at 1.3?ms intervals contained a large peak at 11?Hz. Crop lysimeter data produced similar peaks at frequencies greater than 1?Hz. An effective method for eliminating this noise source is arithmetic averaging of the data, which should be acquired sufficiently rapidly to avoid aliasing. The PSD also increased with decreasing frequency in the range 1.0–0.1?Hz. This noise was addressed by Savitsky–Golay (SG) filtering using 7-, 11-, and 15-point filters. Each filter was applied to the same data set consisting of 2,560 measurements taken during a 1-min interval every 10?min over a 26.3-h period. Noise reduction factors, defined as the ratio of standard deviation of filtered lysimeter mass to standard deviation of unfiltered mean values of lysimeter mass for subsequences of the same data, were 0.90, 0.88, and 0.86 for the 7-, 11-, and 15-point filters, respectively. For the daytime data only, the factors were 0.88, 0.85, and 0.83. The SG filters were more effective during daytime when most of the lysimeter ET occurs. These methods are simple enough to be programmed into commercially available dataloggers for real time filtering. Hourly averages of the standard deviations of lysimeter mass measurements bear a distinct nonlinear relationship to hourly mean wind speed confirming earlier suppositions that wind loading causes noise in counterbalanced weighing lysimeters.     

Diesel exhaust particles modulate the tight junction protein occludin in lung cells in vitro

Background  

Using an in vitro triple cell co-culture model consisting of human epithelial cells (16HBE14o-), monocyte-derived macrophages and dendritic cells, it was recently demonstrated that macrophages and dendritic cells create a transepithelial network between the epithelial cells to capture antigens without disrupting the epithelial tightness. The expression of the different tight junction proteins in macrophages and dendritic cells, and the formation of tight junction-like structures with epithelial cells has been demonstrated. Immunofluorescent methods combined with laser scanning microscopy and quantitative real-time polymerase chain reaction were used to investigate if exposure to diesel exhaust particles (DEP) (0.5, 5, 50, 125 μg/ml), for 24 h, can modulate the expression of the tight junction mRNA/protein of occludin, in all three cell types.     

Semiconductor properties and redox responses at a-C:N thin film electrochemical electrodes

The semiconductor capacitances of the nitrogen-doped amorphous carbon (a-C:N) materials with different sp³/sp² C ratios were studied as a function of electrode potential in a-C:N/aqueous electrolyte systems. This dependence of capacitance on electrode potential in aqueous 0.1 M NaOH shows that the investigated a-C:N materials are intrinsic semiconductors. The space-charge layers inside the a-C:N electrodes behave similar to a Helmholtz layer because of the presence of surface states when the electrolytes contain O₂ or anions other than OH⁻. The lower density and mobility of carriers of materials with a higher sp³ C fraction within the a-C:N material causes a suppression of redox reactions, and the lower density of carriers contributes to a lower capacitance.