Kritische Erfolgsfaktoren f��r die Gestaltung serviceorientierter Informationssysteme

Service orientation has been a major buzz-word in recent years. While the buzz is on a decline, organizations are slowly, but steadily moving towards service oriented designs. However, service orientation turns out to be as much of a managerial challenge as of a technical one. The most important complexity drivers in the service oriented design of information systems seem to be (a) inconsistent design goals of stakeholders and (b) the pursuit of exhaustive service orientation coverage. This research focuses on the following two questions: (1) What are the characteristics of successful implementations of service oriented information systems, and (2) what are the critical success factors influencing, driving and/or determining these characteristics? Data of an empirical analysis is used to test a set of cause-effect relationship hypotheses based on nine latent variables. In the core of this model we differentiate the variables ??overall service orientation infrastructure success?? and ??service orientation project success??. The hypothesized interrelationships between the nine variables lead to a causal model which is proven to hold.     

Requirements Engineering f��r Product Service Systems

In recent years, manufacturing companies and service providers have moved towards offering customer-specific problem solutions. These integrated bundles usually consist of hardware, software, and service components and are called product service systems (PSS) or hybrid products. Since the success of the resulting solution depends on the understanding of all requirements, requirements engineering (RE) has become a key factor. The article analyzes the state of the art of RE for PSS based on an extensive literature review in the domains of product-, software-, and service engineering. For this, criteria are derived from the characteristics of PSS and from the task area of RE in the life cycle of PSS. Based on these criteria we analyze the most established RE approaches for their suitability for PSS. An important finding is that integrated/interdisciplinary approaches for RE are missing. Moreover, the maturity of RE approaches in the three domains varies significantly. All analyzed approaches heavily rely on concepts and solution characteristics of their own domain so that a transfer to other domains is hardly possible. This literature review lays the foundation for successful RE for PSS and especially for future research aiming at combining and integrating RE approaches and models of product-, software-, and service engineering. Such requirement models could connect concepts of single domains and enable an integrated and seamless RE for PSS.     

Peroxiredoxin 2 as a chemotherapy responsiveness biomarker candidate in osteosarcoma revealed by proteomics

Purpose : We aimed to identify novel chemotherapy responsiveness biomarkers for osteosarcoma (OS) by investigating the global protein expression profile of 12 biopsy samples from OS patients. Experimental design : Six patients were classified as good responders and six as poor responders, according to the Huvos grading system. The protein expression profiles obtained by 2‐D DIGE consisted of 2250 protein spots. Results : Among them, we identified 55 protein spots whose intensity was significantly different (Bonferroni adjusted p‐value<0.01) between the two patient groups. Mass spectrometric protein identification demonstrated that the 55 spots corresponded to 38 distinct gene products including peroxiredoxin 2 (PRDX 2). Use of a specific antibody against PRDX 2 confirmed the differential expression of PRDX 2 between good and poor responders, while PRDX 2 levels as measured by Western blotting correlated highly with their corresponding 2‐D DIGE values. The predictive value of PRDX 2 expression was further confirmed by examining an additional four OS cases using Western blotting. Conclusions and clinical relevance : These results establish PRDX 2 as a candidate for chemotherapy responsiveness marker in OS. Measuring PRDX 2 in biopsy samples before treatment may contribute to more effective management of OS.     

Der Stand der Forschung zur Erfolgsmessung von Informationssystemen

Measuring information systems (IS) success is of great interest to both researchers and practitioners. This article examines multidimensional approaches to measuring IS success and explores the current state of IS success research through a literature review and by classifying articles published between 2003 and 2007. Based on a total of 41 academic journal and conference publications, the relevant research carried out is identified, while the research results are categorized, consolidated, and discussed. The results show that the dominant empirical research analyzes the individual impact of a certain type of information system by ascertaining users’ evaluation of it by means of surveys and then applying structural equation modeling. The DeLone and McLean Information Systems Success Model is the main theoretical basis of the reviewed empirical studies. This article provides researchers with a comprehensive review and structuring of IS success research. Furthermore, opportunities for additional development are identified and future research directions suggested.     

Treiber der Adoption SaaS-basierter Anwendungen

Software-as-a-Service (SaaS) is said to become an important cornerstone of the Internet of Services. However, while some market research and IT provider firms fervently support this point of view, others already conjure up the failure of this on-demand sourcing option. Oftentimes based on weak empirical data and shaky reasoning, these inconsistent perspectives lack scientific rigor and neglect to present a more differentiated picture of SaaS-adoption. This study seeks to deepen the understanding of factors driving the adoption of Software-as-a-Service (SaaS). Grounded in transaction cost theory, the resource-based view, and the theory of planned behavior, the authors develop a research model to assess SaaS-adoption at the application level. Survey data of 297 firms in Germany with 374 valid response items across different industries were collected to test the theoretical model. Our analysis revealed that patterns of the decision on SaaS-adoption differ across application types. Social influence, attitude toward SaaS-adoption, adoption uncertainty, and strategic value turned out to be the strongest and most consistent drivers across all application types. Furthermore, it was found that firm size does not matter in SaaS-adoption, since large enterprises and small- and medium-sized companies had similar adoptation rates. Overall, this study provides relevant findings that IT vendors can use to better appeal to potential companies that consider adopting SaaS.     

Outsourcing der Informationsverarbeitung im Mittelstand: Test eines multitheoretischen Kausalmodells

In this paper determinants of information systems (IS) outsourcing are deduced from transaction cost economic theory, resource-based theory and power theory. They are summarized in a theoretical framework which is tested using a sample of small and medium sized enterprises (SMEs) in Germany. The results show that internal performance and know-how deficits vis-à-vis external service providers are key determinants that explain why different IS functions are outsourced to varying degrees in SMEs. Moreover, the determinants of IS functions were found to partially differ between IS functions. Revised reprint of an article from WIRTSCHAFTSINFORMATIK 43(4)2001:339–350.     

WI – Call for PapersHeft 3/2010High-Impact Requirements Engineering

Ohne Zusammenfassung This article is also available in English via http://www.springerlink.com and http://www.bise-journal.org: BISE – Call for Papers, Issue 3/2010, High-Impact Requirements Engineering. Bus Inf Syst Eng. doi: .     

Betriebsinformatik und Wirtschaftsinformatik als notwendige anwendungsbezogene Ergänzung einer allgemeinen Informatik – Vorschläge zur Verbesserung der akademischen Ausbildung auf dem Gebiet der automatisierten Datenverarbeitung in der Bundesrepublik Deutschland

Zusammenfassung  Nachdruck eines Aufsatzes aus elektronische datenverarbeitung 11(11)1969:544–548. This article is also available in English via and : Grochla E (2008) Corporate Information Systems Engineering and Business and Information Systems Engineering as a Necessary Application-Oriented Extension of General Computer Science – Proposals for Enhancing Academic Education in the Field of Automated Data Processing in the Federal Republic of Germany. Bus Inf Syst Eng. doi .

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Wirtschaftsinformatik zwischen Wissenschaft und Unternehmertum

One of the major success indicators for applied research sciences is the rate of transfer from research into practice. Only if concrete and economically successful products are derived from research results, such sciences can induce an impact. However, this process of innovation mandatorily needs entrepreneurship. Within the domain of business information systems, the two German enterprises SAP AG and IDS Scheer AG demonstrate that linking research and innovation is the key to lasting success in the information technology markets. German industry has significant disadvantages on the cost of human resources. Therefore it can be only successful with products that incorporate a high degree of innovation and that are consequently highly priced. But the invention of such products needs scientific research as a source of inspiration. Germany has a highly developed infrastructure of research facilities and organizations. However, they need to be better coordinated and aligned with business needs. Vice versa, enterprises need to actively approach the scientific community in order to clearly formulate their demand. Such a strategy needs changes on all sides. To achieve a change in the domain of science, it is necessary to change the profile of leading researchers, such as full professors. They should incorporate attributes of an entrepreneur and be profiled more as a research manager that tries to anticipate future needs and to develop its unit in terms of research subjects as well as personnel and financial resources. Consequently, the process of application, selection and review of leading researchers should be more oriented on processes that are common in enterprises. E. g. external head-hunters can be involved in the searching and assessing process in order to get the best qualified person for the research vacancy. Also enterprises need to change their attitude towards scientific research. In order to foster this process, executives could be invited to advisory and supervisory boards of research organisations. Furthermore, those executives must be proactively informed about the research activities and results in order to attract their interest and to show potentials for a transfer into products. There is still a long way in the hunt for innovation leadership and all these suggestions can only be a starting point.