Epigenetic Regulation of the Hippocampus,with Special Reference to Radiation Exposure

The hippocampus is crucial in learning, memory and emotion processing, and is involved in the development of different neurological and neuropsychological disorders. Several epigenetic factors, including DNA methylation, histone modifications and non-coding RNAs, have been shown to regulate the development and function of the hippocampus, and the alteration of epigenetic regulation may play important roles in the development of neurocognitive and neurodegenerative diseases. This review summarizes the epigenetic modifications of various cell types and processes within the hippocampus and their resulting effects on cognition, memory and overall hippocampal function. In addition, the effects of exposure to radiation that may induce a myriad of epigenetic changes in the hippocampus are reviewed. By assessing and evaluating the current literature, we hope to prompt a more thorough understanding of the molecular mechanisms that underlie radiation-induced epigenetic changes, an area which can be further explored.     

除尘器新型褶式滤筒的结构优化及系列化设计

以新型褶式滤筒为研究对象,选取滤筒褶数N_2、褶夹角θ、褶高h、过滤风速v为影响因子,除尘器压力损失为响应值,基于响应曲面法分析影响因子对压力损失的影响,建立滤筒除尘器压力损失的预测模型并得到滤筒褶皱结构最优参数。以滤筒内径D、筒体高度D_1为标准尺寸,依据相关国家标准设计滤筒筒体部分;以锥体高度D_2、锥体上圆直径D_3为系列尺寸,利用尺寸变化法设计锥体部分;通过Access软件建立滤筒产品数据库。结果表明:当θ=5.2°,N_2=50,v=0.01 m/s,h=0.035 m时,除尘器压力损失最低;当D_1=1 000 mm,D=320 mm时,D_2和D_3最佳值分别为600,130 mm,故采用D_2/D_1=0.6,D_3/D=0.4的比值设计相应滤筒锥体系列。     

支持CSFB的MSC改造规模预测方法探讨

通过对CSFB语音方案原理的分析,结合业务模型及网络安全等方面的考虑,提出了一种支持4G CSFB的MSC改造规模预测方法,为端局后续建设提供了参考.     

Single-Crystalline TiO2(B) Nanobelts with Unusual Large Exposed {100} Facets and Enhanced Li-Storage Capacity

The {100} facet of single-crystalline TiO₂(B) is an ideal platform for inserting Li ions, but it is hard to be obtained due to its high surface energy. Here, the single-crystalline TiO₂(B) nanobelts from H₂Ti₃O₇ with nearly 70% {100} facets exposed are synthesized, which significantly enhances Li-storage capacity. The first-principle calculations demonstrate an ab in-plane 2D diffusion through the exposed {100} facets. As a consequence, the nanobelts can significantly accommodate Li ions in LiTiO₂ formula with specific capacity up to 335 mAh g⁻¹, which is in good agreement with the electrochemical characterizations. Coating with conductive and protective poly(3,4-ethylenedioxythiophene)-poly(styrenesulfonate), the cut-off discharge voltage is as low as 0.5 V, leading to a capacity of 160.7 mAh g⁻¹ after 1500 cycles with a retention rate of 66% at 1C. This work provides a practical strategy to increase the Li-ion capacity and cycle stability by tailoring the crystal orientation and nanostructures.     

浅谈大断面巷道掘进技术的实践与体会

该文针对当前矿井炮掘巷道大断面掘进普遍存在掘进施工较慢的实际,结合公司实际情况,有针对性地提出了解决的办法。     

Operating Range Scheduled Robust Dahlin Algorithm to Typical Industrial Process with Input Constraint

International Journal of Control, Automation and Systems - There is a class of typical nonlinear industrial process, which can be characterized by a first-order inertia plus pure delay model in an...     

Multi-objective layout optimization for an orbital propellant depot

Structural and Multidisciplinary Optimization - The overall layout optimization design of an orbital propellant depot involves the optimization of shape, size, and positions of propellant tanks in...     

黑匣子高温测试仪的开发

采用物质的相变吸热原理，可以将高温环境传人保温箱的热量重新排回至高温环境，有效地提高了保温箱的抗高温能力，并对保温箱的隔热性能做了简单的理论推算和测温反向试验。温度测试仪选用超低功耗CPU，具有体积小、耗电少的优点，使黑匣子高温测试仪在运行过程中具有很好的安全可靠性。