Thermal radiation and slip effects on MHD stagnation point flow of non-Newtonian nanofluid over a convective stretching surface

The present analysis examines the combine effects of thermal radiation and velocity slip along a convectively nonlinear stretching surface. Moreover, MHD effects are also considered near the stagnation point flow of Casson nanofluid. Slipped effects are considered with the porous medium to reduce the drag reduction at the surface of the sheet. Main structure of the system is based upon the system of partial differential equations attained in the form of momentum, energy, and concentration equations. To determine the similar solution system of PDEs is rehabilitated into the set of nonlinear ordinary differential equations (ODEs) by employing compatible similarity transformation. Important physical parameters are acquired through obtained differential equations. To determine the influence of emerging parameters, resulting set of ODE’s in term of unknown function of velocity, temperature, and concentration are successfully solved via Keller’s box-scheme. All the obtained unknown functions are discussed in detail after plotting the results against each physical parameter. To analyze the behavior at the surface: skin friction, local Nusselt and Sherwood numbers are also illustrated against the velocity ratio parameter A, Brownian motion Nb, thermophoresis Nt, and thermal radiation parameters R. Results obtained from the set of equations described that skin friction is decreasing function of A, and local Nusselt and Sherwood number demonstrate the significant influenced by Brownian motion Nb, thermophoresis Nt, and radiation parameters R.

     

Disease Differentiation and Monitoring of Anti-TNF Treatment in Rheumatoid Arthritis and Spondyloarthropathies

Rheumatoid arthritis (RA), ankylosing spondylitis (AS), and psoriatic arthritis (PsA) are comprehensive immunological disorders. The treatment of these disorders is limited to ameliorating the symptoms and improving the quality of life of patients. In this study, serum samples from RA, AS, and PsA patients were analyzed with metabolomic tools employing the 1H NMR method in combination with univariate and multivariate analyses. The results obtained in this study showed that the changes in metabolites were the highest for AS > RA > PsA. The study demonstrated that the time until remission or until low disease activity is achieved is shortest (approximately three months) for AS, longer for RA and longest for PsA. The statistically common metabolite that was found to be negatively correlated with the healing processes of these disorders is ethanol, which may indicate the involvement of the gut microflora and/or the breakdown of malondialdehyde as a cell membrane lipid peroxide product.     

Investigation of a KcsA Cytoplasmic pH Gate in Lipoprotein Nanodiscs

The bacterial potassium channel KcsA is gated by pH, opening for conduction under acidic conditions. Molecular determinants responsible for this effect have been identified at the extracellular selectivity filter, at the membrane–cytoplasm interface (TM2 gate), and in the cytoplasmic C-terminal domain (CTD), an amphiphilic four-helix bundle mediated by hydrophobic and electrostatic interactions. Here we have employed NMR and EPR to provide a structural view of the pH-induced open-to-closed CTD transition. KcsA was embedded in lipoprotein nanodiscs (LPNs), selectively methyl-protonated at Leu/Val residues to allow observation of both states by NMR, and spin-labeled for the purposes of EPR studies. We observed a pHinduced structural change between an associated structured CTD at neutral pH and a dissociated flexible CTD at acidic pH, with a transition in the 5.0–5.5 range, consistent with a stabilization of the CTD by channel architecture. A double mutant constitutively open at the TM2 gate exhibited reduced stability of associated CTD, as indicated by weaker spin–spin interactions, a shift to higher transition pH values, and a tenfold reduction in the population of the associated “closed” channels. We extended these findings for isolated CTD-derived peptides to full-length KcsA and have established a contribution of the CTD to KcsA pH-controlled gating, which exhibits a strong correlation with the state of the proximal TM2 gate.     

A Requirements Driven Framework for Benchmarking Semantic Web Knowledge Base Systems

A key challenge for the semantic Web is to acquire the capability to effectively query large knowledge bases. As there will be several competing systems, we need benchmarks that will objectively evaluate these systems. Development of effective benchmarks in an emerging domain is a challenging endeavor. In this paper, we propose a requirements driven framework for developing benchmarks for semantic Web knowledge base systems (SW KBSs). In this paper, we make two major contributions. First, we provide a list of requirements for SW KBS benchmarks. This can serve as an unbiased guide to both the benchmark developers and personnel responsible for systems acquisition and benchmarking. Second, we provide an organized collection of techniques and tools needed to develop such benchmarks. In particular, the collection contains a detailed guide for generating benchmark workload, defining performance metrics, and interpreting experimental results     

Dust‐induced shading on photovoltaic modules

The effect of dust on photovoltaic modules is investigated with respect to concentration and spectral transmittance. Samples were collected in the form of raw dust as well as accumulated dust on exposed sheets of glass at different tilt angles. Spectral transmittance of the samples was determined. Transmittance variation between top, middle and bottom was identified for samples collected at different inclinations, where the worst case was seen at a tilt angle of 30^o with a non‐uniformity of 4.4% in comparison with 0.2% for the 90° tilt. The measured data showed a decrease in transmittance at wavelengths <570 nm. Integrating this with measured spectral responses of different technologies demonstrates that wide band‐gap thin‐film technologies are affected more than, for example crystalline silicon technologies. The worst case is amorphous silicon, where a 33% reduction in photocurrent is predicted for a dust concentration of 4.25 mg/cm². Similarly, crystalline silicon and CIGS technologies are predicted to be less affected, with 28.6% and 28.5% reductions in photocurrent, respectively. The same procedure was repeated with varying Air Mass (AM), tilt angle and dust concentration values to produce a soiling ratio table for different technologies under different AM, tilt angle and dust concentration values. Copyright © 2012 John Wiley & Sons, Ltd.     

Adaptive memetic method of multi-objective genetic evolutionary algorithm for backpropagation neural network

Neural Computing and Applications - In recent years, multi-objective evolutionary optimization algorithms have shown success in different areas of research. Due to their efficiency and power, many...     

Extracting the Optical Parameters of the Fabricated (Al/Bare Borosilicate Crown Glass,BK-7/Ag) Multiple Layers

Significant effort has been devoted in this work to convert bare glass substrate with high transmittance, into reflective layers to know its suitability for modern applications. The glass substrate has been carefully chosen for its durability, high permeability, and ability to withstand any external stresses as a result of the accumulation of layers that reduce its permeability to convert it with the thin films coated on it into reflective materials. In parallel, the thin layer to be coated on the substrate is selected from films that can withstand external influences and their great optical properties, not to mention that they are cheap and can produce highly reflective surfaces. The optical measurements (transmittance and reflectance spectra) have been performed in the UV, Vis and NIR regions of the spectrum, that is, in the range between 300 and 1200 nm. Such measurements have been made for the bare glass substrate, the glass substrate with the Al (top side), and the glass substrate with Ag on it (bottom side), and then the optical measurements have been made for the three layers. The corresponding optical parameters of each layer have been calculated and ultimately a reflective layer with high electrical conductivity and excellent optical properties has been obtained that can be adapted for different application purposes.

     

Pre-Crystallization Criteria and Triple Crystallization Kinetic Parameters of Amorphous–Crystalline Phase Transition of As40S45Se15 Alloy

Journal of Inorganic and Organometallic Polymers and Materials - This framework focuses mainly on a detailed study of the pre-crystallization criteria that characterize the As40S45Se15 glassy alloy...