深层优质碎屑岩储层全生命周期分析方法论

油气勘探领域的深层是指沉积盆地中埋深在3 500~4 500 m及以深的地层。在含油气盆地的深层碎屑岩储层中，优质储层是重要的勘探目标。优质储层具有大量孔隙，其形成与沙或砂岩的沉积条件、埋藏方式、区域温压场、膏盐岩效应等多种因素有关。通过系统研究全球不同区域不同时代不同类型深层碎屑岩储层，提出优质深层碎屑岩储层的全生命周期研究方法，即从储层形成演变的全部时间出发，将深部储层的形成过程划分为早期剥蚀搬运沉积阶段、中期埋藏阶段、中期或/和晚期改造阶段，从全生命周期的尺度分阶段综合分析深层碎屑岩储层的形成及演化过程，推演在地质历史时期中的优质储层演化时序及发育阶段、分布位置。     

A Wearable Respiration and Pulse Monitoring System Based on PVDF Piezoelectric Film

A novel wearable sensor system was developed for monitoring respiration and pulse using polyvinylidene fluoride (PVDF) piezoelectric films as sensor materials. Due to the different signal intensity between respiration and pulse, a “double-sided arch” structure and a “thin-shell” structure were designed and fabricated as substrates for the respiratory sensor and pulse sensor, respectively. These sensors installed on belts can be easily tied on the chest, abdomen, or wrist for comfortable fit. In order to obtain clear respiratory and pulse signals from the sensor patch, some high-quality signal processing modules were designed. The digital signals were transmitted to a computer via Bluetooth and displayed by LabVIEW software. The fundamental principle and functional verification of the developed sensor system were described in this study. By comparing the sensor signals from the proposed structure with those of flat structure, it can be concluded that the proposed sensor is more sensitive and stable than its flat counterpart. In addition, the whole sensor system has the features of ease of use and comfortable to wear. All these make the proposed sensor system a promising sensing device for respiration and pulse real time monitoring.     

New amphoteric flocculant containing beta-cyclodextrin,synthesis, charaterization and decolorization properties

To react with the cationic monomer, N-trimethylaminoethylmethacrylate chloride (TMAEMC), a β-CD derivative carrying vinyl carboxylic acid groups (β-CD-MAH) was designed and synthesized via esterfying reaction between β-CD and maleic anhydride (MAH). Whereafter, a water-soluble amphoteric flocculant, the copolymer of TMAEMC and β-CD-MAH (β-CD-MAH-TMAEMC) has been synthesized by means of free radical copolymerization using the ammonium persulfate (APS) and sodium bisulfite (SBS) redox system as the initiator. The copolymer structure was demonstrated by FT-IR, ¹H NMR, SEM characterizations. Its excellent flocculated decolorization properties were evaluated with Acid Light Yellow 2G solutions using a jar test method. With the mass ratio of 1/10 (w/w) between the flocculant and dye, and at pH 4 and 20 °C of the initial dye solution, the maximum color removal reached. The charge neutralization played a dominant role during the flocculated decolorization process, although the inclusion of dye molecules into the cavities of β-CD well maintained in side chain of β-CD-MAH-TMAEMC also contributed to the conglomerates and floccules.     

Megasonic agitation for enhanced electrodeposition of copper

In this paper we propose an agitation method based on megasonic acoustic streaming to overcome the limitations in plating rate and uniformity of the metal deposits during the electroplating process. Megasonic agitation at a frequency of 1 MHz allows the reduction of the thickness of the Nernst diffusion layer to less than 600 nm. Two applications that demonstrate the benefits of megasonic acoustic streaming are presented: the formation of uniform ultra-fine pitch flip-chip bumps and the metallisation of high aspect ratio microvias. For the latter application, a multi-physics based numerical simulation is implemented to describe the hydrodynamics introduced by the acoustic waves as they travel inside the deep microvias.     

Stress-assisted crystallisation in anodic titania

The relationship between the microstructural and internal stress evolution during Ti anodising is discussed. Samples anodised galvanostatically to 12 V and 40 V, corresponding to different stages of the internal stress evolution, were examined by in-plane and cross-section transmission electron microscopy. Electron diffraction patterns have been complemented with stoichiometry data obtained from energy loss near edge structure spectra. The sample anodised to 40 V was observed to consist of two regions, with a crystallised inner region adjacent to the metal/oxide interface. Crystallisation of this region is associated with the presence of large compressive internal stresses which build up during anodising up to 12 V.     

Microstructure and mechanical properties of soy protein/agar blend films: Effect of composition and processing methods

The present work prepared a series of soy protein isolate/agar blend films containing 33% glycerol as plasticizer by solution casting and thermo-molding methods. The microstructure and mechanical properties of the blend films were evaluated in relation to the agar/protein ratio as well as the processing methods. Experimental results revealed that hydrogen bonding interactions existed between soy protein and agar. The casting films possessed more homogeneous interfaces compared with the molding films, leading to the superior mechanical properties than those molding films. Owing to the rigid three-dimensional network formed by the agar, the tensile strength of casting blend films was enhanced. With the increase of agar in the casting blend films, the crosslinking density increased and was responsible for the variations in tensile strength.     

预变形对Al-Zn-Mg铝合金组织及力学性能的影响

系统研究了预变形温度对Al-Zn-Mg铝合金微观组织结构及力学性能的影响。运用光学显微镜和透射电镜观察了微观组织,扫描电镜表征了拉伸断口形貌,X射线衍射仪测试了宏观织构构成,万能拉伸试验机测试了力学性能。结果表明,在400 ℃的热轧温度下,力学性能指标最佳,屈服强度和抗拉强度分别达到325 MPa和455 MPa,伸长率达到14%。不同热轧温度下的拉伸试样断口均呈现为韧性断裂,断口处均存在数量和尺寸不一的韧窝。400 ℃热轧变形温度下,晶粒内部的位错缠结消失,形成了晶界附近规则排列的位错墙;450 ℃时,晶内的位错消失,主要为再结晶晶粒。在350 ℃和400 ℃热轧变形温度下,织构中存在明显的剪切织构,包括旋转立方织构{001}<110>和黄铜R织构{111}<112>和{111}<110>。450 ℃热轧变形温度下,出现明显的再结晶织构Cube_ND {001}<310>。     

奥希替尼获得性耐药的研究进展

奥希替尼作为第三代表皮生长因子受体酪氨酸激酶抑制剂,对表皮生长因子受体（EGFR）T790M突变型肺腺癌有显著疗效。随着临床研究的深入,奥希替尼的耐药逐渐出现。如何应对奥希替尼耐药已成为临床工作者必须关注的问题。本文就奥希替尼获得性耐药机制及应对措施的最新研究进展进行综述。     

脉冲处理对Al-6Zn-3Mg-2Cu合金铸轧板组织及性能的影响

研究了常规铸轧过程中施加20、50和150Hz频率,电流强度为400A的脉冲电流对Al-6Zn-3Mg-2Cu合金铸轧板的组织及力学性能的影响。结果表明,经20Hz的脉冲电流处理后,Al-Zn-Mg-Cu合金铸轧板偏析情况大为改善,微观组织显著细化;150Hz脉冲电流对铸轧板的组织影响不大;铝合金中τ相广泛分布,呈网状或岛状;同时,经20Hz脉冲电流处理的铸轧板抗拉强度可达320MPa,是常规铸轧板强度的1.3倍;样品具有脆性断裂特征,脉冲处理后韧性有所提高。     

雪崩击穿条件下4.5kV IGBT器件的背面优化研究

The static avalanche breakdown behavior of 4.5 kV high-voltage IGBT is studied by theory analysis and experiment. The avalanche breakdown behaviors of the 4.5 kV IGBTs with different backside structures are investigated and compared by using the curve tracer. The results show that the snap back behavior of the breakdown waveform is related to the bipolar PNP gain, which leads to the deterioration of the breakdown voltage. There are two ways to optimize the backside structure, one is increasing the implant dose of the N C buffer layer, the other is decreasing the implant dose of the P C collector layer. It is found that the optimized structure is effective in suppressing the snap back behavior and improving the breakdown characteristic of high voltage IGBT.