High-utility and diverse itemset mining

High-utility Itemset Mining (HUIM) finds patterns from a transaction database with their utility no less than a user-defined threshold. The utility of an itemset is defined as the sum of the utilities of its items. The utility notion enables a data analyst to associate a profit score with each item and thereof to a pattern. We extend the notion of high-utility with diversity to define a new pattern type called High-utility and Diverse pattern (HUD). The notion of diversity of a pattern captures the extent of the different categories covered by the selected items in the pattern. An application of diverse-pattern lies in the recommendation task where a system can recommend to a customer a set of items from a new class based on her previously bought items. Our notion of diversity is easy to compute and also captures the basic essence of a previously proposed diversity notion. The existing algorithm to compute frequent-diverse patterns is 2-phase, i.e., in the first phase, frequent patterns are computed, out of which diverse patterns are filtered out in the second phase. We, in this paper, give an integrated algorithm that efficiently computes high-utility and diverse patterns in a single phase. Our experimental study shows that our proposed algorithm is very efficient as compared to a 2-phase algorithm that extracts high-utility itemsets in the first phase and filters out the diverse itemsets in the second phase.

     

Processing Dependence of Texture, and Critical Properties of YBa2Cu3O7−δ Films on RABiTS Substrates by a Non-Fluorine MOD Method

YBa₂Cu₃O_{7− δ} (YBCO or Y123) films on rolling-assisted biaxially textured substrates (RABiTS) were prepared via a fluorine-free metallorganic deposition (MOD) through spin coating, burnout, and high temperature anneal. The effects of substrate texture and surface energy of the CeO₂ cap layer were investigated. Except for the commonly accepted key factors, such as the textures of substrate and buffer layers, we found some other factors, for example, the deposition temperature of the cap layer, are also critical to the epitaxial growth of Y123 phase. With the CeO₂ cap layer deposited at relative high temperature of 700°C, a critical current density, J _c, over 1 MA/cm² has been demonstrated for the first time on Ni-RABiTS by a fluorine-free MOD method. Whereas for samples with CeO₂ cap layers deposited at a lower temperature of 600°C, even though XRD data showed a better texture on these buffer layers, texture degradations of YBCO grains under the optimized processing conditions were observed and a lower oxygen partial pressure around 40 ppm was necessary for the epitaxial growth of Y123 phase. As a result, J _c fell to 0.45 MA/cm² at 77 K. The observed phenomena points to the change of surface energy and reactivity of the CeO₂ cap layer with respect to the CeO₂ deposition temperature. In this paper, the YBCO phase diagram was also summarized.     

Application of orthogonal collocations to some transport phenomena problems in co-axial cylinders and spheres

Collocation methods are developed for the solution of some differential equation models for transport phenomena problems in one-and two-dimensions in co-axial annuli of spherical and cylindrical shapes. General formulae are developed to obtain orthogonal polynomials over an arbitrary interval using two types of weighting functions. The convergence and accuracy of the methods are demonstrated using two test problems, i.e., calculation of effectiveness factors in (a) a spherical pellet with peripherally deposited catalyst and (b) a Raschig ring type cylindrical catalyst pellet. Comparisons of results obtained from the present methods with analytic solutions for the first-order reactions indicate good agreement. Numerical solutions are also obtained for the second-and the third-order reactions for which analytic solutions are not available. Results obtained in terms of a new Thiele modulus involving the ratio of volume of peripherally deposited part of catalyst to exterior surface area indicate that this normalization brings effectiveness factor versus Thiele modulus curves close together for co-axial spherical and long cylindrical pellets, as it does for these geometries without the inner co-axial portion.     

Effects of cellular pharmacology on drug distribution in tissues

The efficacy of targeted therapeutics such as immunotoxins is directly related to both the extent of distribution achievable and the degree of drug internalization by individual cells in the tissue of interest. The factors that influence the tissue distribution of such drugs include drug transport; receptor/drug binding; and cellular pharmacology, the processing and routing of the drug within cells. To examine the importance of cellular pharmacology, previously treated only superficially, we have developed a mathematical model for drug transport in tissues that includes drug and receptor internalization, recycling, and degradation, as well as drug diffusion in the extracellular space and binding to cell surface receptors. We have applied this "cellular pharmacology model" to a model drug/cell system, specifically, transferrin and the well-defined transferrin cycle in CHO cells. We compare simulation results to models with extracellular diffusion only or diffusion with binding to cell surface receptors and present a parameter sensitivity analysis. The comparison of models illustrates that inclusion of intracellular trafficking significantly increases the total transferrin concentration throughout much of the tissue while decreasing the penetration depth. Increasing receptor affinity or tissue receptor density reduces permeation of extracellular drug while increasing the peak value of the intracellular drug concentration, resulting in "internal trapping" of transferrin near the source; this could account for heterogeneity of drug distributions observed in experimental systems. Other results indicate that the degree of drug internalization is not predicted by the total drug profile. Hence, when intracellular drug is required for a therapeutic effect, the optimal treatment may not result from conditions that produce the maximal total drug distribution. Examination of models that include cellular pharmacology may help guide rational drug design and provide useful information for whole body pharmacokinetic studies.     

Effect of Ni Doping at Pd Site in Nb<Subscript>2</Subscript>PdS<Subscript>5</Subscript> Superconductor

The superconducting properties of Nb₂PdS₅ superconductor have been investigated with Ni doping at Pd site All the bulk polycrystalline Nb₂Pd_1?xNi_x S ₅ (0 = x ≤ 0.10) samples are crystallized in singlephase monoclinic structure. The electrical resistivity and magnetic measurements of Nb₂Pd_1?xNi_x S ₅ (0 = x ≤ 0.15) were carried out to study the variation of superconducting critical parameters with Ni doping. Superconductivity in Nb₂PdS₅ sample completely disappears for x ≥ 0.15. We observed that the ratio of upper critical field to transition temperature decreases with increasing Ni concentration. Also, the magnetization study of Nb₂Pd_1?xNi_x S ₅ (0 = x ≤ 0.15) samples shows similar superconducting behaviour. In summary, the superconductivity in Nb₂PdS₅ sample is slightly varying with partial doping of Ni at Pd site in Nb₂PdS₅ superconductor.     

Transvaginal power Doppler angiography of the fetal brain

BACKGROUND AND OBJECTIVES: The stratum corneum of some of the scaly (parakeratotic) diseases was examined with light and scanning electron microscopy (SEM) with the purpose to reveal the importance of this layer in the diagnosis of some of the diseases associated with the formation of scales. MATERIALS AND METHODS: Two biopsies of the skin surface were taken: one, obtained from 80 patients with various parakeratotic scaly diseases and from 25 control subjects, was processed for light microscopy; the other biopsy for SEM was taken from 10 control subjects and 25 patients. The diagnoses of these patients were: psoriasis (5 patients), erythrodermic psoriasis (2 subjects), parapsoriasis (5 patients), pityriasis rubra pilaris (5 subjects), pityriasis rosea (3 subjects), and seborrheic dermatitis (5 subjects). RESULTS: The light microscopic studies showed that normal corneocytes are of polygonal shape with their largest diameter measuring 42 microns; these cells lacked nuclei. All parakeratotic cells appeared bizarre in shape, smaller than normal, and the cells contained a nucleus. With SEM, normal cells appeared relatively regular in size and shape, trabeculated, and had a flat surface. Cells examined in all the diseases revealed various sizes, outlines, and trabeculae. Specific surface patterns (print) of diseased cells were: "fish-scale" in psoriasis; "marbled" in parapsoriasis, "rocky stone" in pityriasis rubra pilaris; "heart-shaped" in seborrheic dermatitis, and semicrystalloid in pityriasis rosea. CONCLUSIONS: Parakeratosis is characterized not only by the retention of the nucleus in keratinocytes, but is also characterized by a cell of smaller size. The specific print of a disease helps in the diagnosis. The print will change with different stages of a disease.     

An Optimizing Compiler for Parallel Chemistry Simulations

Well designed domain specific languages have three important benefits: (1) the easy expression of problems, (2) the application of domain specific optimizations (including parallelization), and (3) dramatic improvements in productivity for their users. In this paper we describe a compiler and parallel runtime system for modeling the complex kinetics of rubber vulcanization and olefin polymerization that achieves all of these goals. The compiler allows the development of a system of ordinary differential equations describing a complex vulcanization reaction or single-site olefin polymerization reaction—a task that used to require months—to be done in hours. A specialized common sub-expression elimination and other algebraic optimizations sufficiently simplify the complex machine generated code to allow it to be compiled—eliminating all but 8.0% of the operations in our largest program and enabling over 60 times faster execution on our largest benchmark codes. The parallel runtime and dynamic load balancing scheme enables fast simulations of the model.     

A constrained non-linear optimization model for fuzzy pairwise comparison matrices using teaching learning based optimization

Non-linear optimization models have been recently proposed to derive crisp weights from fuzzy pairwise comparison matrices. In this paper, a TLBO (Teaching Learning Based Optimization) based solution is presented for solving an optimization model as a system of non-linear equations to derive crisp weights from fuzzy pairwise comparison matrices in AHP (Analytic Hierarchy Process). This fuzzy-AHP method is named as TLBO-1. It has been found that TLBO-1 can lead to inconsistent or less consistent weights. To solve the problem of inconsistent weights, a new constrained non-linear optimization model is proposed in this paper. This model is based on the min-max approach for fuzzy pairwise comparison ratios of weights. TLBO is again used to solve this optimization model, and crisp weights are derived. This fuzzy AHP method is named as TLBO-2. The effectiveness of the proposed model is illustrated by three examples. For each example, the consistency of the derived crisp weights is compared with other optimization models. The results show that the TLBO-2 method can derive more consistent weights for the fuzzy AHP based Multi-Criteria Decision Making (MCDM) systems as compared to the other optimization models.     

Condition Monitoring Parameters for Fault Diagnosis of Fixed Axis Gearbox: A Review

Condition monitoring of gearboxes which is considered as a key element of rotating machines ensures to continuously reduce and eliminate cost, unscheduled downtime and unexpected breakdowns. Although, a lot of work on condition monitoring and fault diagnosis of fixed-axis gearbox has been reported in the literature, however only a few have found their way to industrial applications. The ability of condition statistical indicators is to provide accurate and precise information about the health of various components at different levels of damage. In this paper, frequently used condition indicators are addressed domain-wise and their characteristics are stated. This paper presents the review of work to provide a wide and good reference for researchers to be utilized. The structure of a fixed-axis gearbox in addition to the unique behaviors and fault characteristics of fixed-axis gearbox has been recognized and represented. By extensively reviewing and categorizing important papers and articles, this paper is able to summarize the conditional monitoring indicators on basis of adopted methodologies. Lastly, open problems are stated and further research prospects pointed out.     

Dynamic vs. Oblivious Routing in Network Design

Consider the robust network design problem of finding a minimum cost network with enough capacity to route all traffic demand matrices in a given polytope. We investigate the impact of different routing models in this robust setting: in particular, we compare oblivious routing, where the routing between each terminal pair must be fixed in advance, to dynamic routing, where routings may depend arbitrarily on the current demand. Our main result is a construction that shows that the optimal cost of such a network based on oblivious routing (fractional or integral) may be a factor of Ω(log n) more than the cost required when using dynamic routing. This is true even in the important special case of the asymmetric hose model. This answers a question in (Chekuri, SIGACT News 38(3):106–128, 2007), and is tight up to constant factors. Our proof technique builds on a connection between expander graphs and robust design for single-sink traffic patterns (Chekuri et al., Networks 50(1):50–54, 2007).