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41.
This article has 2 goals: to provide additional evidence that exposure to ideological online news media contributes to political misperceptions, and to test 3 forms this media‐effect might take. Analyses are based on representative survey data collected during the 2012 U.S. presidential election (N = 1,004). Panel data offer persuasive evidence that biased news site use promotes inaccurate beliefs, while cross‐sectional data provide insight into the nature of these effects. There is no evidence that exposure to ideological media reduces awareness of politically unfavorable evidence, though in some circumstances biased media do promote misunderstandings of it. The strongest and most consistent influence of ideological media exposure is to encourage inaccurate beliefs regardless of what consumers know of the evidence.  相似文献   
42.
We present a corpus-based prosodic analysis with the aim of uncovering the relationship between dialogue acts, personality and prosody in view to providing guidelines for the ECA Greta’s text-to-speech system. The corpus used is the SEMAINE corpus, featuring four different personalities, further annotated for dialogue acts and prosodic features. In order to show the importance of the choice of dialogue act taxonomy, two different taxonomies were used, the first corresponding to Searle’s taxonomy of speech acts and the second, inspired by Bunt’s DIT++, including a division of directive acts into finer categories. Our results show that finer-grained distinctions are important when choosing a taxonomy. We also show with some preliminary results that the prosodic correlates of dialogue acts are not always as cited in the literature and prove more complex and variable. By studying the realisation of different directive acts, we also observe differences in the communicative strategies of the ECA depending on personality, in view to providing input to a speech system.  相似文献   
43.
Type 2 diabetes mellitus (T2DM) is an important risk factor for cardiovascular disease (CVD)—the leading cause of death in the United States. Yet not all subjects with T2DM are at equal risk for CVD complications; the challenge lies in identifying those at greatest risk. Therapies directed toward treating conventional risk factors have failed to significantly reduce this residual risk in T2DM patients. Thus newer targets and markers are needed for the development and testing of novel therapies. Herein we review two complementary MS-based approaches—mass spectrometric immunoassay (MSIA) and MS/MS as MRM—for the analysis of plasma proteins and PTMs of relevance to T2DM and CVD. Together, these complementary approaches allow for high-throughput monitoring of many PTMs and the absolute quantification of proteins near the low picomolar range. In this review article, we discuss the clinical relevance of the high density lipoprotein (HDL) proteome and Apolipoprotein A-I PTMs to T2DM and CVD as well as provide illustrative MSIA and MRM data on HDL proteins from T2DM patients to provide examples of how these MS approaches can be applied to gain new insight regarding cardiovascular risk factors. Also discussed are the reproducibility, interpretation, and limitations of each technique with an emphasis on their capacities to facilitate the translation of new biomarkers into clinical practice.  相似文献   
44.
Prior research has documented that IT investment increases market returns. Economic theories predict such returns to be recognized in accounting profitability; this relationship remains ambiguous in prior literature. We reexamine the relationship between IT investment and firm profitability. Our approach is unique in that we examine complementarities between distinct IT components. We document that a firm’s investments in IT components exhibit different impacts on its profitability conditional on the level of investments in complementary components.  相似文献   
45.
Despite all the financial resources that are directed to support and acquire learning technologies, the results have been generally disappointing. Faculty are eager to use technology but lack the technical skills, ability, and experience. Library staff includes a talent tool rich in Information and Communication Technologies (ICT)/WEB 2.0 technical expertise and experience. In terms of content sourcing and procurement, library technical services and selection staff have broad knowledge of the marketplace for online information and content as well as experience in licensing access. They have a firm grasp of the transaction process, workflows, pricing, and licensing negotiations. Content development and sourcing inevitably involves access management, online storage, copyright, and licensing—things at which libraries are good. ICT deployment is changing teaching and learning on campuses, and the roles of those involved in teaching and learning are also changing. Whether formally through mandated library services, or informally through back channels, library staff are supporting faculty new technology use as well as faculty teaching materials content sourcing and procurement.  相似文献   
46.
In the Galapagos Islands of Ecuador, one of the greatest threats to the terrestrial ecosystem is the increasing number and areal extent of invasive species. Increased human presence on the islands has hastened the introduction of plant and animal species that threaten the native and endemic flora and fauna. Considerable research on invasive species in the Galapagos Islands has been conducted by the Charles Darwin Foundation. We complement that work through a spatially- and spectrally-explicit satellite assessment of an important invasive plant species (Psidium guajava — guava) on Isabela Island that integrates diverse remote sensing systems, data types, spatial and spectral resolutions, and analytical and image processing approaches. QuickBird and Hyperion satellite data are processed to characterize the areal extent and spatial structure of guava through the following approaches: (1) QuickBird data are classified through a traditional pixel-based approach (i.e., an unsupervised classification approach using the ISODATA algorithm), as well as an Object-Based Image Analysis (OBIA) approach; (2) multiple approaches for spectral “unmixing” of the Hyperion hyper-spectral data are assessed to construct spectral end-members from QuickBird data using linear and non-linear mixture modeling approaches; and (3) landscape pattern metrics are calculated and compared for the pixel-based, object-based, and spectral unmixing approaches. The spectral–spatial characteristics of guava are interpreted relative to management strategies for the control of guava and the restoration of natural ecosystems in the Galapagos National Park.  相似文献   
47.
Given a graph with edges colored Red and Blue, we study the problem of sampling and approximately counting the number of matchings with exactly k Red edges. We solve the problem of estimating the number of perfect matchings with exactly k Red edges for dense graphs. We study a Markov chain on the space of all matchings of a graph that favors matchings with k Red edges. We show that it is rapidly mixing using non-traditional canonical paths that can backtrack. We show that this chain can be used to sample matchings in the 2-dimensional toroidal lattice of any fixed size with k Red edges, where the horizontal edges are Red and the vertical edges are Blue. An extended abstract appeared in J.R. Correa, A. Hevia and M.A. Kiwi (eds.) Proceedings of the 7th Latin American Theoretical Informatics Symposium, LNCS 3887, pp. 190–201, Springer, 2006. N. Bhatnagar’s and D. Randall’s research was supported in part by NSF grants CCR-0515105 and DMS-0505505. V.V. Vazirani’s research was supported in part by NSF grants 0311541, 0220343 and CCR-0515186. N. Bhatnagar’s and E. Vigoda’s research was supported in part by NSF grant CCR-0455666.  相似文献   
48.
Karlin  Kenyon  Randall 《Algorithmica》2008,36(3):209-224
Abstract. We present the first optimal randomized online algorithms for the TCP acknowledgment problem [3] and the Bahncard problem [5]. These problems are well known to be generalizations of the classical online ski-rental problem, however, they appeared to be harder. In this paper we demonstrate that a number of online algorithms which have optimal competitive ratios of e/(e-1) , including these, are fundamentally no more complex than ski rental. Our results also suggest a clear paradigm for solving ski-rental-like problems.  相似文献   
49.
Electron tomography (ET) combines electron microscopy and the principles of tomographic imaging in order to reconstruct the three-dimensional structure of complex biological specimens at molecular resolution. Weighted back-projection (WBP) has long been the method of choice since the reconstructions are very fast. It is well known that iterative methods produce better images, but at a very costly time penalty. In this work, it is shown that efficient parallel implementations of iterative methods, based primarily on data decomposition, can speed up such methods to an extent that they become viable alternatives to WBP. Precomputation of the coefficient matrix has also turned out to be important to substantially improve the performance regardless of the number of processors used. Matrix precomputation has made it possible to speed up the block-iterative component averaging (BICAV) algorithm, which has been studied before in the context of computerized tomography (CT) and ET, by a factor of more than 3.7. Component-averaged row projections (CARP) is a recently introduced block-parallel algorithm, which was shown to be a robust method for solving sparse systems arising from partial differential equations. It is shown that this algorithm is also suitable for single-axis ET, and is advantageous over BICAV both in terms of runtime and image quality. The experiments were carried out on several datasets of ET of various sizes, using the blob model for representing the reconstructed object.  相似文献   
50.
This study is an empirical investigation of problematic instant messaging (IM) use among university students in Singapore. It adapts Caplan's (2005) theoretical framework of problematic Internet use (PIU) to the context of problematic IM use by linking pre-existing human dispositions to cognitive-behavioral symptoms and negative outcomes of improper IM use. Four new factors—oral communication apprehension, polychronicity, perceived inconvenience of using offline communication means, and trait procrastination—were tested as predictors of problematic IM use. The results provided strong support for Caplan's theoretical framework of PIU and indicated that oral communication apprehension and perceived inconvenience of using offline means were significant predictors of problematic IM use, whereas polychronicity and trait procrastination were not. The implications of these findings are discussed.  相似文献   
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