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Development of polyampholyte hydrogels based on laponite for electrically stimulated drug release
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Polyampholyte hydrogels (PAHs) composed of laponite, polyacrylamide and poly(3‐acrylamidopropyl)trimethylammonium chloride crosslinked with ethylene glycol dimethacrylate were synthesized and characterized for their sensitivity to external conditions and their ability to control the release of the active drug agent paracetamol. Three PAHs were synthesized by taking the weight ratio of laponite to total monomer as 7, 15 and 29%. PAHs were characterized using Fourier transform infrared spectroscopy, thermogravimetric analysis and swelling measurements carried out in various media. Equilibrium and pulsatile swelling studies were performed on all hydrogels to determine to what extent the hydrogels would respond to changes in environmental pH, ionic strength and electric field, and how fast that response would be. Paracetamol was loaded into the hydrogels, and was released into buffered solutions as a function of pulsatile changes in pH and electric field. © 2014 Society of Chemical Industry 相似文献
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Satellite networks provide global coverage and support a wide range of services, low Earth orbit (LEO) satellites provide short round-trip delays and are becoming increasingly important. One of the challenges in LEO satellite networks is the development of specialized and efficient routing algorithms. In this work, a datagram routing algorithm for LEO satellite networks is introduced. The algorithm generates minimum propagation delay paths. The performance of the algorithm is evaluated through simulations. The robustness issues of the algorithm are also discussed 相似文献
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Recep Kotan Dr Ahmet Cakir Fatih Dadasoglu Tuba Aydin Ramazan Cakmakci Hakan Ozer Saban Kordali Ebru Mete Neslihan Dikbas 《Journal of the science of food and agriculture》2010,90(1):145-160
BACKGROUND: The aims of this study were to examine the chemical composition of the essential oils and hexane extracts of the aerial parts of Satureja spicigera (C. Koch) Boiss., Thymus fallax Fisch. & CA Mey, Achillea biebersteinii Afan, and Achillea millefolium L. by GC and GC–MS, and to test antibacterial efficacy of essential oils and n‐hexane, chloroform, acetone and methanol extracts as an antibacterial and seed disinfectant against 25 agricultural plant pathogens. RESULTS: Thymol, carvacrol, p‐cymene, thymol methyl ether and γ‐terpinene were the main constituents of S. spicigera and T. fallax oils and hexane extracts. The main components of the oil of Achillea millefolium were 1,8‐cineole, δ‐cadinol and caryophyllene oxide, whereas the hexane extract of this species contained mainly n‐hexacosane, n‐tricosane and n‐heneicosane. The oils and hexane extracts of S. spicigera and T. fallax exhibited potent antibacterial activity over a broad spectrum against 25 phytopathogenic bacterial strains. Carvacrol and thymol, the major constituents of S. spicigera and T. fallax oils, also showed potent antibacterial effect against the bacteria tested. The oils of Achillea species showed weak antibacterial activity. Our results also revealed that the essential oil of S. spicigera, thymol and carvacrol could be used as potential disinfection agents against seed‐borne bacteria. CONCLUSION: Our results demonstrate that S. spicigera, T. fallax oils, carvacrol and thymol could become potentials for controlling certain important agricultural plant pathogenic bacteria and seed disinfectant. Copyright © 2009 Society of Chemical Industry 相似文献
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Recep Ali Kumbasar 《Journal of Industrial and Engineering Chemistry》2010,16(2):207-213
In present study, selective extraction of cadmium from acidic leach solutions, containing various heavy metal ions, by emulsion liquid membrane (ELM) is studied. For this reason, the zinc plant copper cake was leached with sulfuric acid and main acidic leach solution containing Zn(II), Cu(II), Fe(II), Cd(II), Co(II) and Ni(II) ions was obtained. After Zn(II), Cu(II), Fe(II) and Cd(II) ions in the acidic leach solution were separated, the important parameters influencing the extent of cadmium extraction were investigated and optimum conditions were determined. Cadmium extraction was influenced by number of parameters like initial metal ion concentration, mixing speed, phase ratio, extractant concentration, surfactant concentration, the stripping solution type and concentration, and the feed solution acid concentration. The optimum values of parameter above mentioned were used and cadmium in the acidic leach solution containing 650 mg Cd/L, 365 mg Co/L, 535 mg Ni/L, and 1260 mg Zn/L was almost completely extracted within 10 min. The results showed that it is possible to extract 99% of cadmium after 10 min contact time by using ELM from aqueous solutions, containing Fe(II), Al(III), Cu(II), Zn(II), Pb(II), Co(II) and Ni(II) ions, at the optimum operating conditions. 相似文献
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Ismet Ozturk Serkan Sahan Ugur Sahin Lutfiye Ekici Assoc. Prof. Osman Sagdic 《Journal für Verbraucherschutz und Lebensmittelsicherheit》2010,5(3-4):453-457
In this study, antiradical and antimicrobial activity, total phenolic, mineral and heavy metal content of Morchella conica Pers. were determined in the methanolic extracts of dried M. conica collected from wild-grown edible mushroom in the Mediterranean region from Turkey. Free radical scavenging activity was determined to be 43.72 ± 0.13% DPPH decoloration, however, total phenolic activity to be 20.64 ± 0.33 mg GAE/g dry ext. sample. The antimicrobial activity of the extracts was tested against fourteen microorganism including 12 bacteria and 2 yeasts. It was determined that the mushroom extracts had no effect against the bacteria and yeasts. Antimicrobial effect was determined only against Staphylococcus aureus ATCC 29213. M. conica was determined to contain some heavy metals such as arsenic (As), mercury (Hg), cadmium (Cd), lead (Pb), chromium (Cr) and nickel (Ni) in the concentrations of 0.25, 0.06, 0.20, 1.20, 0.70 and 1.10 (mg/kg dw), respectively. Potassium (K), phosphorus (P) and magnesium (Mg) contents were determined to be 20,400, 13,250, and 1,600 (mg/kg dw), respectively, being higher than those of the other minerals in the M. conica extracts. 相似文献
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Scientometrics - The study utilizes a unique dataset of 16,575 research papers published in 68 national Business and Economics journals to investigate editorial bias towards insiders in Turkish... 相似文献