Preparation and applications of novel fluoroalkyl end-capped acrylic acid oligomers/silica nanocomposites-encapsulated fullerenes

Fluoroalkyl end-capped acrylic acid oligomers/fullerenes nanocomposites reacted smoothly with tetraethoxysilane (TEOS) and silica nanoparticles under alkaline conditions to give fluoroalkyl end-capped oligomers/silica composites-encapsulated fullerenes. Interestingly, these isolated fluorinated composites were found to afford nanometer size-controlled colloidal particles with a good dispersibility in a variety of organic solvents including water. More interestingly, these fluorinated silica nanocomposites-encapsulated fullerenes were applied to a new type of surface modification agent, and these nanocomposites were able to disperse well above the poly(methyl methacrylate) films to exhibit not only surface active property imparted by fluorine but also a unique characteristic related to fullerenes in the nanocomposites on the surface, effectively.     

One Step Synthesis of Gold‐Loaded Radial Mesoporous Silica Nanospheres and Supported Lipid Bilayer Functionalization: Towards Bio‐Multifunctional Sensors

A simple synthetic route is developed to achieve gold functionalized radial mesoporous silica nanoparticles (Au‐MsNP) synthesized by a one step procedure fully compatible with basic conditions required for the preparation of monodispersed nanospheres. In a second step, Au‐MsNP particles have been coated with phospholipid bilayers in order to design an advanced biofunctional platform with the gold metallic nanoparticles previously grown into the pore channels and responsible for a plasmonic activity relevant for biosensing. The size of Au‐MsNP is checked by dynamic light scattering while zeta potential measurements reflect their surface charge. The particle morphology is characterized by transmission and scanning electron microscopy and the Si/Au ratios are obtained from energy dispersive X‐ray analysis. The textural properties of Au‐MsNP, specific surface area and pore size, are determined from N₂ adsorption. The supported bilayers are achieved from vesicles of different phospholipids incubated with Au‐MsNP particles. The coating efficiency is investigated by zeta potential and cryo‐ transmission electron microscopy. The plasmonic activities of bare Au‐MsNP particles and coated lipid bilayer Au‐MsNP platform are evidenced for two model systems: direct adsorption of bovine serum albumin and molecular recognition events between avidin molecules and biotin receptors integrated in the supported lipid bilayer.     

Conductance fluctuations in gold point contacts: an atomistic picture

This paper concerns an experimental and theoretical study of the transition between two consecutive conductance plateaus as obtained in breaking gold contact experiments. The experimental measurements performed at 100?K with a scanning tunneling microscope and variable elongation speeds show that the transitions between consecutive plateaus can appear in the conductance traces as an abrupt conductance step, a smooth quasicontinuous change or as large amplitude conductance fluctuations. The theoretical calculations based on a non-orthogonal tight-binding Hamiltonian have shown that for a given deformation there are several structures having close and competing energies.We discuss the relation between the temperature, sampling frequency, stretching speed and energy barriers which can explain the conditions for the observation of the three kinds of conductance traces.     

Transforming sugars into fat – lipid biosynthesis using different sugars in Yarrowia lipolytica

In an era of ever‐increasing energy demands, a promising technology is being developed: the use of oleaginous microorganisms such as Yarrowia lipolytica to convert waste materials into biofuels. Here, we constructed two Y. lipolytica strains that displayed both increased lipid accumulation and more efficient use of biomass‐derived sugars, including glucose, fructose, galactose and inulin. The first strain, Y. lipolytica YLZ150, was derived from the French wild‐type strain W29. It had inhibited triacylglycerol mobilization (?tgl4 ) and β‐oxidation (?pox1–6 ), and it overexpressed GPD1 , DGA2 , HXK1 , the native Leloir pathway, SUC2 from Saccharomyces cerevisiae and INU1 from Kluyveromyces marxianus . The second strain, Y. lipolytica Y4779, was derived from the Polish A‐101 strain. It had inhibited β‐oxidation (?mfe2 ) and overexpressed GPD1 , DGA1 , HXK1 , YHT3, SUC2 and INU1 . In the first experiment, strain YLZ150 was batch‐cultured in media containing different hexoses; the highest values for lipid concentration and yield of lipids from the substrate were obtained using fructose (20.3 g dm^?3 and 0.14 g g^?1, respectively). In the second experiment, we grew the two strains in fed‐batch cultures to examine lipid biosynthesis from inulin (a fructose polymer). For Y4779, the lipid concentration was 10.3 g dm^?3 and the yield of lipids from substrate was 0.07 g g^?1; in contrast, for YLZ150, these values were 24 g dm^?3 and 0.16 g g^?1, respectively. The YLZ150 strain is thus able to efficiently exploit glucose, fructose, galactose, sucrose and inulin for lipid biosynthesis. Copyright © 2017 John Wiley & Sons, Ltd.     

Attentional mechanisms driven adaptive quantization and selective bit allocation scheme for H.264/AVC

Rate control algorithm adopted in H.264/AVC reference software shows several shortcomings that have been highlighted by different studies. For instance, in the baseline profile, the frame target bit-rate estimation assumes similar characteristics for all frames and the quantization parameter determination uses the Mean Absolute Difference for complexity estimation. Consequently, an inefficient bit allocation is performed leading to important quality variation of decoded sequences. A saliency-based rate-control is proposed in this paper to achieve bit-rate saving and improve perceived quality. The saliency map of each frame, simulating the human visual attention by a bottom-up approach, is used at the frame level to adjust the quantization parameter and at the macroblock level to guide the bit allocation process. Simulation results show that the proposed attentional model is well correlated to human behavior. When compared to JM15.0 reference software, at the frame level, the saliency map exploitation achieves bit-rate savings of up to 26%. At the MB level and under the same quality constraint, bit-rate improvement is up to 42% and buffer level variation is reduced by up to 71%.     

Kinetic Modeling of “Go Slow” Dialysis in Acute Renal Failure

Go slow” dialysis is a gentle, intermittent hemodialysis therapy for acute renal failure patients, with advantages compared to slow, continuous therapies. It employs a recirculating closed dialysate circuit. A two-pool urea kinetic model is elaborated to determine kinetic parameters from blood and dialysate concentrations. This will allow quantification of the therapy. Variable clearance is included to accurately describe the kinetic process. The model is tested in an acute renal failure patient. Solute removals, as determined from direct dialysis quantification and by the model, are comparable. Variable clearance is not required to determine the kinetic parameters, because the constant mean clearance delivers equal results. The dialysis dose, as defined, allows comparison with chronic renal therapies. It requires solute removal determined from dialysate sampling and time-averaged concentration (TAC) from the urea kinetic modeling. In the test patient, dialysis dose is lower compared to standard thrice-weekly therapies because of its lower efficiency and higher TAC, a result of his highly catabolic state.     

DSM—IV antisocial personality disorder field trial.

The development of the 4th edition of the Diagnostic and Statistical Manual of Mental Disorders (American Psychiatric Association, 1994 ) included 12 field trials to assess proposed revisions. This article provides results from the antisocial personality disorder (APD) field trial that was conducted to obtain data of relevance to the proposals for simplification and for the inclusion of more traditional traits of psychopathy. Provided herein are the results from 4 sites that had sampled from populations of particular relevance to the diagnosis of APD (i.e., prison inmates, psychiatric inpatients, outpatients with substance use disorders, and homeless persons). The results indicated that some items from the 3rd revised Diagnostic and Statistical Manual of Mental Disorders (American Psychiatric Association, 1987) could be deleted without affecting the diagnosis. The field trial provided mixed support for the proposal to include more traditional traits of psychopathy. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Zooming On All Actors: Automatic Focus+Context Split Screen Video Generation

Recordings of stage performances are easy to capture with a high‐resolution camera, but are difficult to watch because the actors' faces are too small. We present an approach to automatically create a split screen video that transforms these recordings to show both the context of the scene as well as close‐up details of the actors. Given a static recording of a stage performance and tracking information about the actors positions, our system generates videos showing a focus+context view based on computed close‐up camera motions using crop‐and zoom. The key to our approach is to compute these camera motions such that they are cinematically valid close‐ups and to ensure that the set of views of the different actors are properly coordinated and presented. We pose the computation of camera motions as convex optimization that creates detailed views and smooth movements, subject to cinematic constraints such as not cutting faces with the edge of the frame. Additional constraints link the close up views of each actor, causing them to merge seamlessly when actors are close. Generated views are placed in a resulting layout that preserves the spatial relationships between actors. We demonstrate our results on a variety of staged theater and dance performances.     

Constrained global optimization for wine blending

Assemblage consists in blending base wines in order to create target wines. Recent developments in aroma analysis allow us to measure chemical compounds impacting the taste of wines. This chemical analysis makes it possible to design a decision tool for the following problem: given a set of target wines, determine which volumes must be extracted from each base wine to produce wines that satisfy constraints on aroma concentration, volumes, alcohol contents and price. This paper describes the modeling of wine assemblage as a mixed constrained optimization problem, where the main goal is to minimize the gap to the desired concentrations for every aromatic criterion. The deterministic branch and bound solvers Couenne and IbexOpt behave well on the wine blending problem thanks to their interval constraint propagation/programming and polyhedral relaxation methods. We also study the performance of other optimization goals that could be embedded in a configuration tool, where the different possible interactions amount to solving the same constraints with different objective functions. We finally show on a recent generic wine blending instance that the proposed optimization process scales up well with the number of base wines.