Verfestigung,Fließfläche und Versetzungsstruktur bei Low-Cycle Fatigue

Cyclic Hardening, Yield Surface and Dislocation Arrangement in Low-Cycle Fatigue In Many technical and structural components stress raisers exist which undergo cyclic plastic deformation. Models have been developed to calculate the strain distribution and the resulting life. They are based on the assumptions that Masing-behaviour, isotropic and kinematic hardening are valid with cyclic pasticity. These assumptions have been examined experimentally. An interpretive connection is made between mechanical yield surface and microscopical arrangement of dislocations in the sense of cyclic hardening behaviour.     

Intervals in generalized effect algebras

A significant property of a generalized effect algebra is that its every interval with inherited partial sum is an effect algebra. We show that in some sense the converse is also true. More precisely, we prove that a set with zero element is a generalized effect algebra if and only if all its intervals are effect algebras. We investigate inheritance of some properties from intervals to generalized effect algebras, e.g., the Riesz decomposition property, compatibility of every pair of elements, dense embedding into a complete effect algebra, to be a sub-(generalized) effect algebra, to be lattice ordered and others. The response to the Open Problem from Rie?anová and Zajac (2013) for generalized effect algebras and their sub-generalized effect algebras is given.     

Pharmaceutical quantification with univariate analysis using transmission Raman spectroscopy

The purpose of this study was to investigate the quantification performance of transmission Raman spectroscopy with univariate analysis. Model dosage forms containing acetaminophen and an excipient, lactose monohydrate, were prepared. The Raman spectra of the tablets were obtained using the modes of transmission, backscattering micro-spectroscopy, and wide area illumination. Calibration curves for quantification of acetaminophen in the tablets were created using peak heights of the Raman spectra. Of the three modes of measurement, the quantitative results by transmission had the highest correlation with those by conventional UV–vis methods. In the validation of quantification by the transmission mode with univariate analysis, a certain degree of daily variation was confirmed. Additionally, quantitative results using peak heights were compared with those of partial least squares (PLSs) multivariate analysis. The root mean square error of prediction (RMSEP) suggested that quantification using PLS provided better precision than the peak height method as expected. However, content uniformity test using large sample sizes by the Raman spectra is not required to be very highly predictive because they usually employ non-parametric criteria and include wide specification ranges. Therefore, univariate analysis using transmission Raman spectroscopy was a suitable quantitative method for conducting content uniformity tests of large sample sizes.     

Investigation of false-positive reactions for CBH351 maize in screening PCR analysis

Examination for CBH351 maize was conducted by the qualitative polymerase chain reaction (PCR) method in maize grain and maize processed foods obtained in the Tokyo area. The numbers of samples possibly positive in the screening test were 7 of 22 (31.8%) for maize grain samples, 4 of 14 (28.6%) for semi-processed foods, 11 of 30 (36.7%) for canned products, 3 of 30 (10.0%) for maize snacks, 3 of 4 (75%) for tacos and 1 of 3 (33.3%) for tortillas. However, CBH351 maize was not detected in the confirmation test. Therefore, the results of the screening test were false-positive. Since the reaction might have been caused by the base sequences of the 3'-end of primers CaM03-5' and CBH02-3' used in the screening test, a new primer pair was designed. The PCR products obtained with the new primer pair TMC2-5'--TMS2-3' were specific for CBH351 and were not obtained with barley, wheat, rice, RRS, Bt11, or Event176. Thus, the new primer pair shows high specificity. CBH351 maize was detected from samples containing at least 0.05% CBH 351 maize DNA by using this primer pair.