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101.
Elena Orban Gabriella Di Lena Maurizio Masci Teresina Nevigato Irene Casini Roberto Caproni Loretta Gambelli Michele Pellizzato 《Journal of the science of food and agriculture》2004,84(14):1929-1938
Quality aspects of oysters (Crassostrea gigas) from a suspended culture in the lagoon of Venice (Valle Dogà) were examined in different seasons over a 1‐year period. Ecophysiological and commercial quality indicators (condition index, content of meat, shell and intervalvar fluid), nutritional quality parameters (proximate and mineral composition, glycogen content, fatty acid profile, cholesterol, plant sterols, fat‐soluble vitamins content) and levels of organic pollutants (polychlorinated biphenyls and organochlorine pesticides) were determined at different times of the year. Seasonal variations were observed in the nutrient content, with particular regard to moisture (ranging from 866.8 g kg?1 in June to 938.8 g kg?1 in September), protein (23.9 g kg?1 in September to 76.6 g kg?1 in June), ash (22.5 g kg?1 in February to 29.5 g kg?1 in July), lipid (3.0 g kg?1 in September to 8.8 g kg?1 in June) and glycogen (0.7 g kg?1 in September to 11.5 g kg?1 in February). In spite of this variability, the nutritional quality of the oysters was generally good, especially just before gamete release when the concentration of nutrients was at its maximum. Low levels of organochlorine chemicals were detected in the edible meat of oysters but, because only a limited number of samples were analysed, no general conclusion can be drawn on the safety of seafood from this area. Copyright © 2004 Society of Chemical Industry 相似文献
102.
Rolling Kanban is the name of a kanban management methodology for batch processes manufacturing environment. Proposed in the early 2000s by FESTO Consulting, for two decades we have lost knowledge both from operative and scientific point of view. Basically, Rolling Kanban means a visual planning methodology based on the production of product-families and variants where: (i) set-up times are reduced between the products of the same family, and (ii) relevant times (dozens of minutes if not even hours) must be considered for changeover between products of different families. In addition, the cyclic production sequence between different product families cannot be maintained. Considering that very few technical information and documents are available about this approach, the main objective of this paper is to retrieve and present, for the first time to the scientific community, the Rolling Kanban methodology. Besides, a real industrial implementation concerning a manufacturer of domestic fittings is discussed as a case study. More specifically, two novel versions of the original Rolling Kanban technique are fully presented to effectively overcome certain limits and criticalities found during its operative use, such as the difficulty to realise a pull production, considering increased set-up time for changeover between products of different families. 相似文献
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105.
Results are presented of an investigation on the polymerizability of functional olefins, such as allylisopropylidene glycerol (AIPG) and undecenylisopropylidene glycerol (UIPG), in the presence of conventional and modified Ziegler-Natta catalysts based on TiCl4 or MgCl2-supported titanium and triisobutylaluminum, hexaisobutyltetraalumoxane, or bisdiethyl-aluminum sulfate. Homopolymerization experiments were performed on AIGP at temperatures of -78, 25, and 50°C; only these at 50°C provided appreciable amounts of polymeric materials insoluble in methanol, whose structures comprise monomeric units derived from opening both dioxolane rings and vinyl double bonds. In spite of all attempts and precautions, polymerization experiments carried out on mixtures of the functional olefins AIPG and UIPG with either 4-methyl-1-pentene or isopropyl vinyl ether gave rise to the homopolymers of the nonfunctional α-olefin and of the vinyl ether, without any appreciable amount of either copolymers or homopolymers of the dioxolane containing monomers. © 1996 John Wiley & Sons, Inc. 相似文献
106.
The mode-matching analysis of rectangular waveguide networks requires a complex segmentation of the structure into simple elements. The way these elements are connected has a strong influence on the computing performance of the code. Moreover, for complex structures the size of the coefficient matrix of the main system can easily reach unaffordable dimensions, so that the use of an efficient solving strategy becomes indispensable. A new approach to the optimum automatic choice of the interconnections is presented, leading to a highly stable and outperforming method of analysis. A Butler 4 × 4 matrix, with six branch guide couplers and four phase shifters, containing 336 uniform waveguide sections and bifurcations, has been studied, and the presented strategy has allowed a performance increase up to two orders of magnitude. © 1996 John Wiley & Sons, Inc. 相似文献
107.
Seigo Nagashima Anderson Azevedo Dutra Mayara Pezzini Arantes Rafaela Chiuco Zeni Carolline Konzen Klein Flvia Centenaro de Oliveira Giulia Werner Piper Isadora Drews Brenny Marcos Roberto Curcio Pereira Rebecca Benicio Stocco Ana Paula Camargo Martins Eduardo Morais de Castro Caroline Busatta Vaz de Paula Andra Novaes Moreno Amaral Cleber Machado-Souza Cristina Pellegrino Baena Lucia Noronha 《International journal of molecular sciences》2022,23(3)
Mast cells (MCs) have relevant participation in inflammatory and vascular hyperpermeability events, responsible for the action of the kallikrein–kinin system (KKS), that affect patients inflicted by the severe form of COVID-19. Given a higher number of activated MCs present in COVID-19 patients and their association with vascular hyperpermeability events, we investigated the factors that lead to the activation and degranulation of these cells and their harmful effects on the alveolar septum environment provided by the action of its mediators. Therefore, the pyroptotic processes throughout caspase-1 (CASP-1) and alarmin interleukin-33 (IL-33) secretion were investigated, along with the immunoexpression of angiotensin-converting enzyme 2 (ACE2), bradykinin receptor B1 (B1R) and bradykinin receptor B2 (B2R) on post-mortem lung samples from 24 patients affected by COVID-19. The results were compared to 10 patients affected by H1N1pdm09 and 11 control patients. As a result of the inflammatory processes induced by SARS-CoV-2, the activation by immunoglobulin E (IgE) and degranulation of tryptase, as well as Toluidine Blue metachromatic (TB)-stained MCs of the interstitial and perivascular regions of the same groups were also counted. An increased immunoexpression of the tissue biomarkers CASP-1, IL-33, ACE2, B1R and B2R was observed in the alveolar septum of the COVID-19 patients, associated with a higher density of IgE+ MCs, tryptase+ MCs and TB-stained MCs, in addition to the presence of intra-alveolar edema. These findings suggest the direct correlation of MCs with vascular hyperpermeability, edema and diffuse alveolar damage (DAD) events that affect patients with a severe form of this disease. The role of KKS activation in events involving the exacerbated increase in vascular permeability and its direct link with the conditions that precede intra-alveolar edema, and the consequent DAD, is evidenced. Therapy with drugs that inhibit the activation/degranulation of MCs can prevent the worsening of the prognosis and provide a better outcome for the patient. 相似文献
108.
In this paper, data are reported for the behaviour of some charcoals during combustion and devolatilization in a thermal analyser. 相似文献
109.
Alessandro Marchioni Roberto Tonelli Alessandro Andreani Gaia Francesca Cappiello Matteo Fermi Fabiana Trentacosti Ivana Castaniere Riccardo Fantini Luca Tabbì Dario Andrisani Filippo Gozzi Giulia Bruzzi Linda Manicardi Antonio Moretti Serena Baroncini Anna Valeria Samarelli Massimo Pinelli Giorgio De Santis Alessandro Stefani Daniele Marchioni Francesco Mattioli Enrico Clini 《International journal of molecular sciences》2022,23(5)
Laryngotracheal stenosis (LTS) is a complex and heterogeneous disease whose pathogenesis remains unclear. LTS is considered to be the result of aberrant wound-healing process that leads to fibrotic scarring, originating from different aetiology. Although iatrogenic aetiology is the main cause of subglottic or tracheal stenosis, also autoimmune and infectious diseases may be involved in causing LTS. Furthermore, fibrotic obstruction in the anatomic region under the glottis can also be diagnosed without apparent aetiology after a comprehensive workup; in this case, the pathological process is called idiopathic subglottic stenosis (iSGS). So far, the laryngotracheal scar resulting from airway injury due to different diseases was considered as inert tissue requiring surgical removal to restore airway patency. However, this assumption has recently been revised by regarding the tracheal scarring process as a fibroinflammatory event due to immunological alteration, similar to other fibrotic diseases. Recent acquisitions suggest that different factors, such as growth factors, cytokines, altered fibroblast function and genetic susceptibility, can all interact in a complex way leading to aberrant and fibrotic wound healing after an insult that acts as a trigger. However, also physiological derangement due to LTS could play a role in promoting dysregulated response to laryngo-tracheal mucosal injury, through biomechanical stress and mechanotransduction activation. The aim of this narrative review is to present the state-of-the-art knowledge regarding molecular mechanisms, as well as mechanical and physio-pathological features behind LTS. 相似文献
110.
Maria Chiara Sportelli Margherita Izzi Daniela Loconsole Anna Sallustio Rosaria Anna Picca Roberto Felici Maria Chironna Nicola Cioffi 《International journal of molecular sciences》2022,23(6)
In 2019, the new coronavirus disease (COVID-19), related to the severe acute respiratory syndrome coronavirus (SARS-CoV-2), started spreading around the word, giving rise to the world pandemic we are still facing. Since then, many strategies for the prevention and control of COVID-19 have been studied and implemented. In addition to pharmacological treatments and vaccines, it is mandatory to ensure the cleaning and disinfection of the skin and inanimate surfaces, especially in those contexts where the contagion could spread quickly, such as hospitals and clinical laboratories, schools, transport, and public places in general. Here, we report the efficacy of ZnO nanoparticles (ZnONPs) against SARS-CoV-2. NPs were produced using an ecofriendly method and fully characterized; their antiviral activity was tested in vitro against SARS-CoV-2, showing a decrease in viral load between 70% and 90%, as a function of the material’s composition. Application of these nano-antimicrobials as coatings for commonly touched surfaces is envisaged. 相似文献