Prevalence of Escherichia coli O157 in cattle and swine in central Mexico

Escherichia coli O157:H7 is a foodborne pathogenic bacterium that can reside undetected in the gastrointestinal tract of cattle because colonization by this bacterium is asymptomatic. Recent research has indicated that swine can carry and transmit this pathogen as well. The development of more advanced and sensitive detection techniques has improved the limit of detection and increased sensitivity for this important pathogen. This study was undertaken to determine the prevalence of E. coli O157 in cattle and swine in Mexico with the more sensitive detection technique of immunomagnetic bead separation. Samples (n = 60 per farm) were taken from four cattle and four swine farms (n = 240 cattle samples, n = 240 swine samples) located throughout central Mexico in October 2001. The prevalence of E. coli O157 was found to be only 1.25% on cattle farms and 2.1% on swine farms. The prevalence in cattle in this study is lower than that reported in the United States and could be related to the lower reported prevalence of E. coli O157 in humans in Mexico. However, further research is needed to verify prevalence throughout other regions of Mexico, as well as prevalence during other seasons of the year.     

Characterization of the mechanism of interaction in ibuprofen-Eudragit RL100 coevaporates

The present study is a preliminary exploration of the affinity between a carboxylic model drug, the nonsteroidal antiinflammatory agent ibuprofen (IBU) and Eudragit RL100 (RL) polymer. Due to the presence of a variable amount of quaternary ammonium groups in this matrix, physical and chemical interaction with the carboxylic drug can occur, which reinforces its scant mechanical dispersion in the polymer network and can ultimately affect its release profile in vitro and in vivo. To study these aspects, IBU was mixed at increasing weight ratios and in different chemical forms (free acid, sodium salt, and n-butyl ester), to investigate further the role of the carboxylic group in the interaction with the RL polymer. Therefore, IBU-RL solid dispersions (coevaporates) were obtained and fully characterized in the solid state through spectroscopic, calorimetric, and x-ray diffractometric analyses. The in vitro release pattern of the drug, in the different chemical states, was studied for the coevaporates, compared with drug-RL physical mixtures, along with drug adsorption profiles from aqueous solutions on the surface of the polymer granules.     

Observation of a Possible Metallic State Induced by a Parallel Magnetic Field in Superconducting Au0.7In0.3 Samples With Very Low Normal-state Sheet Resistance

We report the observation of an apparent metallic state induced by a parallel magnetic field in Au_0.7In_0.3 samples with very low normal-state sheet resistance. These samples can be modeled as a random array of superconductor-normal metal-superconductor (SNS) junctions. For both the thin planar and cylindrical films, the magnetic field was applied parallel to the substrate of the sample and measurement currents. For the mesoscopic rings, however, a perpendicular field was used. Our electrical transport and tunneling measurements suggest that the samples consist of superconducting In-rich islands not linked by Josephson coupling in the metallic state. The physical origin of the metallic state is discussed.      

Game theory and time utility functions for a radio aware scheduling algorithm for WiMAX networks

In WiMAX systems the Base Station scheduler plays a key role as it controls the sharing of the radio resources among the users. The goal of the scheduler is multiple: achieve fair usage of the resources, satisfy the QoS requirements of the users, maximize goodput, and minimize power consumption, and at the same time ensuring feasible algorithm complexity and system scalability. Since most of these goals are contrasting, scheduler designers usually focus their attention on optimizing one aspect only. In this scenario, we propose a scheduling algorithm (called GTS_N\mathrm{GTS_N}) whose goal is to contemporaneously achieve efficiency and fairness, while also taking into account the QoS requirements and the channel state. GTS_N\mathrm{GTS_N} exploits the properties of Time Utility Functions (TUFs) and Game Theory. Simulations prove that the performance of GTS_N,\mathrm{GTS_N}, when compared to that of several well-known schedulers, is remarkable. GTS_N\mathrm{GTS_N} provides the best compromise between the two contrasting objectives of fairness and efficiency, while QoS requirements are in most cases guaranteed. However, the exponential complexity introduced by the game theory technique makes it rather impractical and not computationally scalable for a large number of users. Thus we developed a suboptimal version, named sub-GTS_N.\mathrm{GTS_N}. We show that this version retains most of the features and performance figures of its brother, but its complexity is linear with the number of users.     

Changes in phenolic compounds and colour in pale Sherry wines subjected to fining treatments

 Changes in the concentrations of hydroxybenzoic acids, hydroxycinnamic acids and their esters, monomeric and dimeric derivatives of flavan-3-ol, and flavonols, as well as in the UV-visible absorbances of pale Sherry wines were studied. The wines were subjected to four different fining treatments: casein + bentonite, casein + bentonite + activated charcoal, casein + bentonite + polyvinylpyrrolidone (PVPP) and casein + bentonite + Riduxhigh. Based on the results, the treatments including activated charcoal and PVPP were the most effective at decreasing the overall concentration phenolic compounds, with no significant difference between them. Likewise, these treatments provided the best results in relation to wine colour in the visible spectral region, and particularly at 420 nm, at which wavelength browning compounds are usually measured. Received: 24 March 1997 / Revised version: 11 June 1997     

Paillier''s Trapdoor Function Hides up to O ( n ) Bits

At EuroCrypt '99 Paillier proposed a new encryption scheme based on higher residuosity classes. The new scheme was proven to be one-way under the assumption that computing N -residuosity classes in Z _N2 ^* is hard. Similarly the scheme can be proven to be semantically secure under a much stronger decisional assumption: given w ∈ Z _N2 ^* it is impossible to decide if w is an N -residue or not. In this paper we examine the bit security of Paillier's scheme. We prove that if computing residuosity classes is hard, then given a random w it is impossible to predict the least significant bit of its class significantly better than at random. This immediately yields a way to obtain semantic security without relying on the decisional assumption (at the cost of several invocations of Paillier's original function). In order to improve efficiency we then turn to the problem of simultaneous security of many bits. We prove that Paillier's scheme hides n-b (up to O(n) ) bits if one assumes that computing the class c of a random w remains hard even when we are told that c<2 ^b . We thoroughly examine the security of this stronger version of the intractability of the class problem. An important theoretical implication of our result is the construction of the first trapdoor function that hides super-logarithmically (up to O(n) ) many bits. We generalize our techniques to provide sufficient conditions for a trapdoor function to have this property.     

Effect of the long-term intake of an egg white hydrolysate on the oxidative status and blood lipid profile of spontaneously hypertensive rats

This paper examines the effects of the long-term consumption of egg white hydrolysed with pepsin (hEW) on the antioxidant status and lipid profile of spontaneously hypertensive rats (SHR). The antioxidant capacity was measured by the oxygen radical absorbance capacity (ORAC) and the oxidative status by the malon-dialdehyde (MDA) assay. The lipid profile was analysed spectrophotometrically. The radical-scavenging capacity of the plasma was increased and the MDA concentration in the aorta was decreased in the SHR treated with 0.5 g/kg/day of hEW. Our findings indicate that hEW played an important role in antioxidative defence of SHR and exerted a beneficial effect on the lipid profile, lowering triglycerides and total cholesterol without changing HDL levels. Therefore, hEW may be useful to prevent or reverse abnormalities associated with the metabolic syndrome and its complications, such as hypertension, oxidative stress and hyperlipidemia.     

Redesigning an assembly line through lean manufacturing tools

The implementation of a lean manufacturing strategy represents a robust contribution to the phase sequence that leads to operational excellence and the continuous improvement through the elimination of nonvalue-added activities. Therefore, lean practices contribute substantially to plant operational performance. This paper studies the use of value stream mapping (VSM) as a tool in lean manufacturing implementation and a framework of improvement activities, in particular for an efficient introduction of kanban and milkrun techniques. A case study illustrates VSM use, as well as kanban and milkrun systems application on an assembly line. Finally, the results obtained show the path of improvement, measured through the lean rate (LR) and dock-to-dock time (DtD).