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41.
表面贴装工艺流程的关键工序之一就是焊膏印刷,其工艺控制的好坏直接影响着装配的线路板的质量。通过对印刷工艺参数的分析,利用试验设计的方法来找出关键工艺参数,并加以优化设定,从而为控制工序参数奠定基础。 相似文献
42.
文章提出了一种面向XML文档的基于XMLschema并结合RDF的访问控制模型,它实现了对XML文档的细粒度的安全访问控制,同时提供了对XML文档中associationsecurityobject的安全访问控制。 相似文献
43.
Three-dimensional models, or pharmacophores, describing Euclidean constraints on the location on small molecules of functional
groups (like hydrophobic groups, hydrogen acceptors and donors, etc.), are often used in drug design to describe the medicinal
activity of potential drugs (or ‘ligands’). This medicinal activity is produced by interaction of the functional groups on
the ligand with a binding site on a target protein. In identifying structure-activity relations of this kind there are three
principal issues: (1) It is often difficult to “align” the ligands in order to identify common structural properties that
may be responsible for activity; (2) Ligands in solution can adopt different shapes (or `conformations’) arising from torsional
rotations about bonds. The 3-D molecular substructure is typically sought on one or more low-energy conformers; and (3) Pharmacophore
models must, ideally, predict medicinal activity on some quantitative scale. It has been shown that the logical representation
adopted by Inductive Logic Programming (ILP) naturally resolves many of the difficulties associated with the alignment and
multi-conformation issues. However, the predictions of models constructed by ILP have hitherto only been nominal, predicting
medicinal activity to be present or absent. In this paper, we investigate the construction of two kinds of quantitative pharmacophoric
models with ILP: (a) Models that predict the probability that a ligand is “active”; and (b) Models that predict the actual
medicinal activity of a ligand. Quantitative predictions are obtained by the utilising the following statistical procedures
as background knowledge: logistic regression and naive Bayes, for probability prediction; linear and kernel regression, for
activity prediction. The multi-conformation issue and, more generally, the relational representation used by ILP results in
some special difficulties in the use of any statistical procedure. We present the principal issues and some solutions. Specifically,
using data on the inhibition of the protease Thermolysin, we demonstrate that it is possible for an ILP program to construct
good quantitative structure-activity models. We also comment on the relationship of this work to other recent developments
in statistical relational learning.
Editors: Tamás Horváth and Akihiro Yamamoto 相似文献
44.
45.
The estimation of the link capacity and its available bandwidth in an end-to-end path is crucial for network management, admission
control and flow control for adaptive applications. This paper introduces an estimation mechanism able to accurately estimate
the available bandwidth of all links in an end-to-end path, through its capacity and cross-traffic estimation. The estimation
procedures resort to the dispersions of packet pairs and trains using the concepts of ICMP Timestamp and Traceroute that,
efficiently used together, enable the measurement of the dispersions in all links in the path. These mechanisms were evaluated
through simulation experiments, where we analyzed the influence of the several network parameters on each estimation mechanism.
The results show that these estimation methods are able to accurately estimate both the capacity and the cross-traffic of
all links in a path with moderate length and with low overhead. 相似文献
46.
47.
48.
随着光电器件的广泛应用,微机械光开关成为核心光交换器件的主流。在研发过程中,其器件检测手段成为人们所关注的话题。本文介绍了一种新颖的测量平台,通过高幅值利用单片机控制脉冲频率的方法来选择器件。与当前同类方法相比,具有精度高、可靠性强、成本低、易操作等特点,具有广阔的使用前景。 相似文献
49.
50.
泥化软化性F_5断层是故县大坝坝基范围内最大的一条断层,位于左岸,对左坝肩的稳定极为不利,采用水泥灌浆处理无效,故改用化学灌浆处理。选用EAA化学浆材,采用“优选组合配方综合施灌”的创新施工工艺,效果良好,为今后低渗透性复杂的泥化软化性断层的防渗加固处理,提供了新的依据和途径。 相似文献