Career-Sustaining Behaviors, Satisfactions, and Stresses of Professional Psychologists.

A random sample of licensed psychologists from Illinois (N=286) responded to a survey about career-sustaining behaviors (CSBs) and about satisfactions and stresses they experience at work. The highest rated CSBs were spending time with partner/family, maintaining a balance between personal and professional lives, and maintaining a sense of humor. Overall, more satisfied respondents reported greater importance of CSBs. Female respondents reported significantly greater use of CSBs than male respondents and were more likely to endorse behaviors that were relational or educational in nature, such as participating in personal therapy, spending time with friends, discussing work frustrations with colleagues, seeking case consultation, maintaining regular contact with referral networks, participating in continuing-education programs, reflecting on positive experiences, and engaging in quiet leisure activities. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Potent inhibitors of the MAP kinase p38

The MAP kinase p38 plays a key role in the biosynthesis of the inflammatory cytokines TNF-alpha and IL-1. We have developed a novel series of potent p38 inhibitors that could lead to new methods of treatment for inflammatory diseases such as rheumatoid arthritis and inflammatory bowel disease.     

Berechnung von Wärmespannungen mit der Methode der finiten Elemente

Einfluß von Wärmedehnungen auf das Spannungs- und Dehnungsverhalten fester Körper und Formulierung der Spannungs- und Dehnungsbeziehungen in Matrizenform für ebene und axialsymmetrische Probleme. Überprüfung der Aussagemöglichkeiten des Verfahrens anhand von Anwendungsbeispielen.     

The development of novel and selective p56lck tyrosine kinase inhibitors

Early T-cell receptor mediated signal transduction involves the activation of several tyrosine protein kinases. One of these tyrosine kinases, p56lck, is expressed primarily in T-cells and Natural Killer (NK) cells and has been shown to be critical for their proliferative and effector functions. Indandiones have been identified as a potent and selective chemical class that inhibits p56lck.     

Die Vorbereitung der Probenoberfläche und ihr Einfluß auf das Ergebnis der Elektronenstrahl-Mikroanalyse

Modellversuche und Untersuchungen an Zweistoffsystemen und technischen Legierungen zur Feststellung der Beeinflussung der Mikrosondenanalysen durch verschiedene Ätzverfahren. Prüfung der Anwendbarkeit von Interferenzaufdampfschichten.     

Intramammary pressure and udder firmness during a 72-h interruption of milking to simulate dry-off,with and without feed restriction

The goal of the present study was to quantify the increase of intramammary pressure (IMP) in dry-off during an extended milking interval of 72 h. In particular, we tested the hypothesis that feed restriction (no concentrate and roughage with reduced energy) causes earlier cessation of milk secretion and a lower IMP than continued feeding of the lactational diet. In addition to repeated IMP measurements, we tested a noninvasive method that records udder firmness (UF) via external application of pressure on the udder. Two experimental groups consisted of 10 Holstein cows each, with a daily milk yield of 20 to 25 kg. The restricted group (RG) was changed to restricted feeding on the afternoon of the final milking (0 h), whereas late-lactation feeding was continued in the control group (CG). Both IMP and UF were measured before and after the final milking immediately before milking was stopped for 72 h. These measurements represented IMP and UF levels at 10 h and 0 h milking intervals, respectively. Further measurements were performed at 18, 24, 30, 36, 42, 48, and 72 h after final milking. Milk samples (2 mL) were taken through the IMP catheter at each sampling event, for analysis of somatic cell count (SCC) and serum albumin (SA). Both IMP and UF increased with time, and both parameters peaked at 30 h in CG and at 24 h in RG. The mean IMP from 18 to 72 h, compared with the 10-h IMP (normal milking interval) was higher in CG than in RG. The duration of elevated IMP and UF was prolonged in CG compared with RG (>36 h vs. 12 h). The Pearson correlation between IMP and UF was r = 0.67. Thus, the noninvasive measurement of UF is suitable to replace invasive IMP measurements. However, due to individual differences in udder shape, the correlation between UF and IMP was too low to predict exact IMP levels using UF. Both SCC (presented as logSCC) and SA increased after the final milking until the end of the experiment. The mean increase from 18 to 72 h, compared with levels immediately after final milking, was higher in CG than in RG for SCC but did not differ between treatments for SA. In conclusion, feed restriction causes a faster cessation of milk secretion and therefore limits the increase of IMP at dry-off.