Studies of lipoproteins and fatty acids in maternal and cord blood of two racial groups in Trinidad

The high mortality rate from coronary heart disease (CHD) among Indians compared to Negroes in Trinidad led us to test plasma lipid profiles to see whether dietary or genetic factors might be involved. There were no interracial differences in the composition of plasma cholesterol ester fatty acids of the tested women and neonates. This finding suggests that dietary fat does not account for the interracial difference in CHD, nor does the cause appear to be due to genetic differences in lipid profiles, as there was no significant difference between values for plasma triglycerides, total cholesterol, high density lipoprotein (HDL) cholesterol, apo-I, apo-II, apo B or cholesterol ester fatty acids in the cord blood of each racial group. Blood samples were collected from 69 nonpregnant and 71 postpartum, fasted Negro and Indian women. Also taken were 71 umbilical cord blood samples. The mean triglyceride level was significantly lower in the Negro nonpregnant and postpartum women than in the Indians. HDL cholesterol and apo-I values were lower in the Indian women. There were no significant differences in the total cholesterol and apo B measurements. The triglyceride values for postpartum women were higher than those of the nonpregnant Negroes and Indians (75% and 47%, respectively), whereas the total cholesterol and HDL cholesterol, apo A-I and apo A-II ranged from 9% to 29% higher in the postpartum women. Apo B was about 40% higher postpartum in both ethnic groups. The high CHD rate of Indians in Trinidad cannot be explained by dietary factors, plasma total cholesterol or fatty acid composition. However, the lower level of HDL cholesterol and plasma A-I could play a role in the higher CHD rate in Indians.     

Photochemical degradation of glassy polyesters of low softening point

The photodegradation of polyesters prepared by the reaction of o-phthalic, adipic, and “dimer” acids with ethylene glycol has been studied. The polyesters softened at temperatures in the range of 25–50°C. Polymer films were irradiated in air by means of a medium pressure mercury lamp and the extent of formation of COOH groups determined by infrared spectroscopy. The films were also irradiated in vacuo and in air by means of a high-pressure mercury lamp, and the volatile products, consisting mainly of carbon monoxide and carbon dioxide, were determined by gas chromatography. The results are interpreted in terms of simultaneous Norrish type I and type II decompositions of the polyesters. The type I process accounts for the formation of carbon monoxide and carbon dioxide in the absence of air. The enhanced yield of carbon dioxide in irradiations performed in air is ascribed to the formation of hydroperoxide which undergoes further photolysis. The type II process accounts for the formation of COOH groups. The photodegradation of these glassy polyesters parallels that of crystalline poly(ethylene terephthalate) and is relatively unaffected by changes in composition of the aromatic polyester.     

Length preferences and periodicity in {beta}-strands. Antiparallel edge {beta}-sheets are more likely to finish in non-hydrogen bonded rings

We analysed the length distributions of different types of ß-strandin a high resolution, non-homologous set of 500 protein structures,finding differences in their mean lengths. Antiparallel edgestrands in strand–turn–strand motifs show a preferencefor an even number of residues. This propensity is enhancedif the length is corrected for ß-bulges, which insertan extra residue into the strand. Residues in antiparallel edgeß-strands alternate between being in hydrogen bondedand non-hydrogen bonded rings. Antiparallel edges with an evennumber of residues are more likely to have their final ßresidue in a non-hydrogen bonded ring. This suggests that non-hydrogenbonded rings are intrinsically more stable than hydrogen bondedrings, perhaps because its side chain packing is closer. Therefore,we suggest that a simple way to increase ß-hairpinstability, or the stability of an antiparallel edge strand,is to have a non-hydrogen bonded ring at the end of the strand. Received June 19, 2003; revised October 25, 2003; accepted November 7, 2003     

Orientation effects during the flow of short-fibre reinforced thermoplastics

A study has been carried out to investigate molecular orientation in injection moulded bars of short glass fibre reinforced polypropylene and polyethylene. For the range of fibre concentrations encountered commercially, the fibres do not appear to have any direct effect on the matrix orientation. As the fibre concentration increases, however, the matrix orientation becomes dominated by the orientation of the fibres. These effects are interpreted in terms of current ideas of the rheology of polymer melts during injection moulding and the crystallization of polymers at fibre surfaces.     

Toughening epoxy resins with polyepichlorohydrin

Polyepichlorohydrin (PECH) rubbers were found to toughen epoxy resins based on the diglycidyl ether of bisphenol A (DGEBA) and cured with piperidine. The degree of toughening depends on the molecular weight of the PECH and on the curing temperature. Best toughening was achieved with PECH of the highest nominal molecular weight of 3400 (Hydrin 10 × 2). Hydrin 10 × 1 (nominal molecular weight 1700) did not toughen the epoxy resin unless bisphenol A was also added, whereas Hydrin 10 × 2 toughened it in the absence of bisphenol A. Curing resins containing bisphenol A and Hydrin 10 × 1 at 160°C resulted in a slightly more brittle resin than when cured at 120°C. The effect of PECH rubbers on the T_g, modulus, and hot/wet properties is similar to that of carboxy-terminated butadiene-acrylonitrile rubbers (CTBN). Dynamic mechanical thermal analysis (DMTA) and scanning electron micrographs (SEM) of fractured surfaces show that the PECH separates as a discrete phase during curing. © 1993 John Wiley & Sons, Inc.     

The influence of cure conditions on the morphology and phase distribution in a rubber-modified epoxy resin using scanning electron microscopy and atomic force microscopy

In this paper, we consider the effect of cure conditions on the morphology and distribution of the rubber in a phase separated rubber-modified epoxy resin, which in effect is a two phase composite. Novel aspects of this study were measuring the elastic modulus of the dispersed rubber phase particles by atomic force microscopy (AFM) and verifying the presence of nano-dispersed rubber.The purpose of introducing dispersed rubber particles into the primary phase in these systems is to enhance their toughness. It is known that both the rubber particle size and volume fraction affect the degree to which the epoxy is toughened. It is not known, however, how the specific mechanical properties of the rubber phase itself affect the toughness.The objectives of this study were to: (1) use scanning electron microscopy (SEM) and atomic force microscopy (AFM) to determine the morphology and phase distribution of the rubber particles and (2) to measure the mechanical properties of the rubber particles using AFM. Ultimately, we would like to develop a clear understanding of how the changes in morphology and mechanical properties measured at the micro and nano-scales affect both the elastic modulus and fracture toughness of rubber-modified epoxy polymers.The epoxy system consisted of a diglycidyl ether of bisphenol-A, Epon 828, cured with piperidine and incorporating a liquid carboxyl-terminated acrlonitrile-butadiene rubber (CTBN). The carboxyl groups of the rubber are capable of reacting with the epoxy. The cure conditions considered were based on a statistically designed full factorial curing matrix, with the variables selected being cure temperature, initiator (piperidine) concentration, and rubber acrylonitrile concentration.Each of these primary variables was found to affect the phase distribution that resulted during cure. A statistical analysis of the effect of these variables on the phase morphology showed that the acrylonitrile content (%) of the rubber affected both the rubber particle size and volume fraction. The cure temperature strongly influenced the rubber particle volume fraction and modulus. Volume fractions of the rubber phase of up to 24% were obtained even though the amount of rubber added was only 12.5%. The rubber particle modulus varied from 6.20 to 7.16 MPa. Both the volume fraction and modulus of the rubber particles were found to influence the macroscopic mechanical properties of the composite. While larger volume fractions favor improved toughness, we note that that the toughness is greatest when the particle modulus values do not exceed ∼6.2 MPa. Thus, increased volume fraction by itself may not always result in increased toughness. The particles also must be sufficiently ‘soft’ in order to improve toughness. In the system of interest here, the processing conditions are a key factor in achieving the most appropriate material properties. By inference, this is likely to be the case as well in other rubber-modified thermosets.     

Effects of composition and phase relations on mechanical properties and crystallization of silicate glasses

Crystallization, mechanical properties, and workability are all important for the commercialization and optimization of silicate glass compositions. However, the inter-relations of these properties as a function of glass composition have received little investigation. Soda-lime-silica glasses with Na₂O-MgO-CaO-Al₂O₃-SiO₂ compositions relevant to commercial glass manufacture were experimentally studied and multiple liquidus temperature and viscosity models were used to complement the experimental results. Liquidus temperatures of the fabricated glasses were measured by the temperature gradient technique, and Rietveld refinements were applied to X-Ray powder diffraction (XRD) data for devitrified glasses, enabling quantitative determination of the crystalline and amorphous fractions and the nature of the crystals. Structural properties were investigated by Raman spectroscopy. Acoustic echography, micro-Vicker's indentation, and single-edge-notched bend testing methods were used to measure Young's moduli, hardness, and fracture toughness, respectively. It is shown that it is possible to design lower-melting soda-lime-silica glass compositions without compromising their mechanical and crystallization properties. Unlike Young's modulus, brittleness is highly responsive to the composition in soda-lime-silica glasses, and notably low brittleness values can be obtained in glasses with compositions in the wollastonite primary phase field: an effect that is more pronounced in the silica primary phase field. The measured bulk crystal fractions of the glasses subjected to devitrification at the lowest possible industrial conditioning temperatures indicate that soda-lime-silica glass melts can be conditioned close to their liquidus temperatures within the compositional ranges of the primary phase fields of cristobalite, wollastonite, or their combinations.     

The supremacy of online white supremacists – an analysis of online discussions by white supremacists

A content analysis was conducted on five different white supremacist online forums to observe the discourse and types of activities occurring within. In addition, web link analysis was conducted on the forums to identify the presence of external links being posted and discussed by members. We found that members used the forums primarily for information provision, recruitment and networking. Based on these results, we discuss the implications that online hate speech have within offline settings, and the affects these activities have on Canadian citizens in light of the recent repeal of section 13 of the Canadian Human Rights Act (1985), the primary tool in Canada with which to deal with hate speech and other activities observed. The insights extracted from this research have provided novel insight into the sentiments and activities of the white supremacist movement online, a relatively unexplored venue of hate speech and propaganda online.     

Clustering high dimensional data: A graph-based relaxed optimization approach

There is no doubt that clustering is one of the most studied data mining tasks. Nevertheless, it remains a challenging problem to solve despite the many proposed clustering approaches. Graph-based approaches solve the clustering task as a global optimization problem, while many other works are based on local methods. In this paper, we propose a novel graph-based algorithm “GBR” that relaxes some well-defined method even as improving the accuracy whilst keeping it simple. The primary motivation of our relaxation of the objective is to allow the reformulated objective to find well distributed cluster indicators for complicated data instances. This relaxation results in an analytical solution that avoids the approximated iterative methods that have been adopted in many other graph-based approaches. The experiments on synthetic and real data sets show that our relaxation accomplishes excellent clustering results. Our key contributions are: (1) we provide an analytical solution to solve the global clustering task as opposed to approximated iterative approaches; (2) a very simple implementation using existing optimization packages; (3) an algorithm with relatively less computation time over the number of data instances to cluster than other well defined methods in the literature.